Publications by authors named "John A Howe"

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Evaluation of a non-nucleoside inhibitor of the RSV RNA-dependent RNA polymerase in translatable animals models.
Michael P Citron, Xiaowei Zang, Andrew Leithead, Shi Meng, William A Rose Ii, John A Howe

J Infect· December 2024

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Novel Pan-Coronavirus 3CL Protease Inhibitor MK-7845: Biological and Pharmacological Profiling.
Nadine Alvarez, Gregory C Adam, John A Howe, Vijeta Sharma, Matthew D Zimmerman

Viruses· July 2024

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Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic.
Valerie W Shurtleff, Mark E Layton, Craig A Parish, James J Perkins, John D Schreier, John A Howe

J Med Chem· March 2024

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Molnupiravir maintains antiviral activity against SARS-CoV-2 variants and exhibits a high barrier to the development of resistance.
Julie M Strizki, John M Gaspar, John A Howe, Beth Hutchins, Hiroshi Mohri

Antimicrob Agents Chemother· January 2024

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Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases.
Victoria A Kleiner, Thierry O Fischmann, John A Howe, Douglas C Beshore, Michael J Eddins

Commun Biol· June 2023

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Staying well when life and living are different.
John A Howe

J Am Vet Med Assoc· June 2020

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COVID-19: Answering the call together.
John A Howe

J Am Vet Med Assoc· May 2020

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We're in this together: helping veterinarians navigate COVID-19.
John A Howe

J Am Vet Med Assoc· April 2020

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Enhancing the wellbeing of the veterinary profession.
John A Howe

J Am Vet Med Assoc· February 2020

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Advocating for appropriate standards for animal drug compounding.
John A Howe

J Am Vet Med Assoc· December 2019

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There should always be a "tech" in team.
John A Howe

J Am Vet Med Assoc· November 2019

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AVMA-sponsored health insurance is back; advocacy to expand to more states continues.
John A Howe

J Am Vet Med Assoc· October 2019

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Continuing our path forward: Working for you, advancing animal health.
John A Howe

J Am Vet Med Assoc· September 2019

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Validation and Development of an Escherichia coli Riboflavin Pathway Phenotypic Screen Hit as a Small-Molecule Ligand of the Flavin Mononucleotide Riboswitch.
Carl J Balibar, Artjohn Villafania, Christopher M Barbieri, Nick Murgolo, Terry Roemer, John A Howe

Methods Mol Biol· February 2019

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Deposition of artificial radionuclides in sediments of Loch Etive, Scotland.
Hamza Al-Qasmi, Gareth T W Law, L Keith Fifield, John A Howe, Tim Brand

J Environ Radioact· July 2018

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Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.
Noreen F Rizvi, John A Howe, Ali Nahvi, Daniel J Klein, Thierry O Fischmann

ACS Chem Biol· March 2018

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Nuclear reprocessing-related radiocarbon (C) uptake into UK marine mammals.
Kieran M Tierney, Graham K P Muir, Gordon T Cook, Johanna J Heymans, Gillian MacKinnon, John A Howe

Mar Pollut Bull· November 2017

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Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.
Hao Wang, Paul A Mann, Li Xiao, Charles Gill, Andrew M Galgoci, John A Howe

Cell Chem Biol· May 2017

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Ecosystem uptake and transfer of Sellafield-derived radiocarbon (C) part 2: The West of Scotland.
Kieran M Tierney, Graham K P Muir, Gordon T Cook, Gillian MacKinnon, John A Howe

Mar Pollut Bull· February 2017

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Ecosystem uptake and transfer of Sellafield-derived radiocarbon (C). Part 1. The Irish Sea.
Graham K P Muir, Kieran M Tierney, Gordon T Cook, Gillian MacKinnon, John A Howe

Mar Pollut Bull· January 2017

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Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitch.
John A Howe, Li Xiao, Thierry O Fischmann, Hao Wang, Haifeng Tang

RNA Biol· October 2016

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Latest Quaternary palaeoceanographic change in the eastern North Atlantic based upon a dinoflagellate cyst event ecostratigraphy.
Rex Harland, Irina Polovodova Asteman, Audrey Morley, Angela Morris, Anthony Harris, John A Howe

Heliyon· May 2016

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Accumulation of Sellafield-derived radiocarbon ((14)C) in Irish Sea and West of Scotland intertidal shells and sediments.
Kieran M Tierney, Graham K P Muir, Gordon T Cook, Gillian MacKinnon, John A Howe

J Environ Radioact· January 2016

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Selective small-molecule inhibition of an RNA structural element.
John A Howe, Hao Wang, Thierry O Fischmann, Carl J Balibar, Li Xiao

Nature· October 2015

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Ecological impacts of large-scale disposal of mining waste in the deep sea.
David J Hughes, Tracy M Shimmield, Kenneth D Black, John A Howe

Sci Rep· May 2015

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