Publications by authors named "Dereje A Negatu"

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Toward a Bactericidal Oral Drug Combination for the Treatment of Lung Disease.
Jickky Palmae Sarathy, Min Xie, Chui Fann Wong, Dereje A Negatu, Suyapa Rodriguez

ACS Infect Dis· April 2025

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Durlobactam to boost the clinical utility of standard of care β-lactams against lung disease.
Dereje A Negatu, Wassihun Wedajo Aragaw, Tewodros T Gebresilase, Sindhuja Paruchuri, Firat Kaya

Antimicrob Agents Chemother· January 2025

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Multidrug tolerance conferred by loss-of-function mutations in anti-sigma factor RshA of .
Wassihun Wedajo Aragaw, Tewodros T Gebresilase, Dereje A Negatu, Véronique Dartois, Thomas Dick

Antimicrob Agents Chemother· December 2024

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Oral β-Lactam Pairs for the Treatment of Mycobacterium avium Complex Pulmonary Disease.
Dereje A Negatu, Sung Jae Shin, Su-Young Kim, Byung Woo Jhun, Véronique Dartois

J Infect Dis· August 2024

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A pairwise approach to revitalize β-lactams for the treatment of TB.
Dereje A Negatu, Wassihun Wedajo Aragaw, Véronique Dartois, Thomas Dick

Antimicrob Agents Chemother· June 2024

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Pharmacological validation of dihydrofolate reductase as a drug target in .
Wassihun Wedajo Aragaw, Dereje A Negatu, Christopher J Bungard, Véronique A Dartois, Abdellatif El Marrouni

Antimicrob Agents Chemother· January 2024

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Characterization of Resistance to Linezolid in Mycobacterium abscessus.
Dereje A Negatu, Wassihun Wedajo Aragaw, Véronique Dartois, Thomas Dick

Microbiol Spectr· August 2023

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Side-by-Side Profiling of Oxazolidinones to Estimate the Therapeutic Window against Mycobacterial Infections.
Dereje A Negatu, Wassihun Wedajo Aragaw, Julianna Cangialosi, Véronique Dartois, Thomas Dick

Antimicrob Agents Chemother· April 2023

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Activity of Oral Tebipenem-Avibactam in a Mouse Model of Mycobacterium abscessus Lung Infection.
Dereje A Negatu, Rubén González Del Río, Mónica Cacho-Izquierdo, David Barros-Aguirre, Joël Lelievre

Antimicrob Agents Chemother· February 2023

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Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus.
Abdeldjalil Madani, Dereje A Negatu, Abdellatif El Marrouni, Randy R Miller, Christopher W Boyce

Antimicrob Agents Chemother· September 2022

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Strongly Bactericidal All-Oral β-Lactam Combinations for the Treatment of Mycobacterium abscessus Lung Disease.
Dereje A Negatu, Matthew D Zimmerman, Véronique Dartois, Thomas Dick

Antimicrob Agents Chemother· September 2022

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Structure-Activity Relationship of Anti- Piperidine-4-carboxamides, a New Class of NBTI DNA Gyrase Inhibitors.
Andreas Beuchel, Dina Robaa, Dereje A Negatu, Abdeldjalil Madani, Nadine Alvarez

ACS Med Chem Lett· March 2022

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Functionalized Dioxonaphthoimidazoliums: A Redox Cycling Chemotype with Potent Bactericidal Activities against .
Kevin T Fridianto, Ming Li, Kiel Hards, Dereje A Negatu, Gregory M Cook

J Med Chem· November 2021

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Piperidine-4-Carboxamides Target DNA Gyrase in Mycobacterium abscessus.
Dereje Abate Negatu, Andreas Beuchel, Abdeldjalil Madani, Nadine Alvarez, Chao Chen

Antimicrob Agents Chemother· July 2021

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Indole Propionic Acid, an Unusual Antibiotic Produced by the Gut Microbiota, With Anti-inflammatory and Antioxidant Properties.
Dereje Abate Negatu, Martin Gengenbacher, Véronique Dartois, Thomas Dick

Front Microbiol· October 2020

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Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in .
Dereje Abate Negatu, Yoshiyuki Yamada, Yu Xi, Mei Lin Go, Matthew Zimmerman

mBio· March 2019

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Whole-Cell Screen of Fragment Library Identifies Gut Microbiota Metabolite Indole Propionic Acid as Antitubercular.
Dereje A Negatu, Joe J J Liu, Matthew Zimmerman, Firat Kaya, Véronique Dartois

Antimicrob Agents Chemother· March 2018

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