Publications by authors named "Mei Lin Go"

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A potent phenylalkylamine disrupts mycobacterial membrane bioenergetics and augments bactericidal activity of bedaquiline.
Zheng Yen Phua, Ming Li, Azhar Ali, Cedric Cheng Sheng Cheong, Kai Jie Goh, Boon Cher Goh, Mei Lin Go

iScience· July 2025

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Targeting transcription factors through an IMiD independent zinc finger domain.
Bee Hui Liu, Miao Liu, Sridhar Radhakrishnan, Meng-Yuan Dai, Chaitanya Kumar Jaladanki, Mei Lin Go

EMBO Mol Med· June 2025

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Targeting transcription factors through an IMiD independent zinc finger domain.
Bee Hui Liu, Miao Liu, Sridhar Radhakrishnan, Chaitanya Kumar Jaladanki, Chong Gao, Mei Lin Go

bioRxiv· January 2024

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PROTAC antibiotics: the time is now.
Jickky Palmae Sarathy, Courtney C Aldrich, Mei-Lin Go, Thomas Dick

Expert Opin Drug Discov· April 2023

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Redox Cycling Dioxonaphthoimidazoliums Disrupt Iron Homeostasis in Mycobacterium bovis Bacillus Calmette-Guérin.
Ming Li, Yoshiyuki Yamada, G Marcela Rodriguez, Thomas Dick, Mei Lin Go

Microbiol Spectr· December 2022

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Alkyltriphenylphosphonium turns naphthoquinoneimidazoles into potent membrane depolarizers against .
Kevin Timothy Fridianto, Gregory Adrian Gunawan, Kiel Hards, Jickky Palmae Sarathy, Gregory M Cook, Mei-Lin Go

RSC Med Chem· December 2022

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High-Content Phenotypic Screen of a Focused TCAMS Drug Library Identifies Novel Disruptors of the Malaria Parasite Calcium Dynamics.
Wanni Chia, Maria G Gomez-Lorenzo, Isabel Castellote, Jie Xin Tong, Rajesh Chandramohanadas, Mei Lin Go

ACS Chem Biol· November 2021

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Functionalized Dioxonaphthoimidazoliums: A Redox Cycling Chemotype with Potent Bactericidal Activities against .
Kevin T Fridianto, Ming Li, Kiel Hards, Dereje A Negatu, Gregory M Cook, Mei-Lin Go

J Med Chem· November 2021

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Infigratinib Is a Reversible Inhibitor and Mechanism-Based Inactivator of Cytochrome P450 3A4.
Lloyd Wei Tat Tang, Jian Wei Teng, Ravi Kumar Verma, Siew Kwan Koh, Lei Zhou, Mei Lin Go

Drug Metab Dispos· September 2021

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Mechanism-Based Inactivation of Cytochrome P450 3A4 and 3A5 by the Fibroblast Growth Factor Receptor Inhibitor Erdafitinib.
Lloyd Wei Tat Tang, Jian Wei Teng, Siew Kwan Koh, Lei Zhou, Mei Lin Go

Chem Res Toxicol· July 2021

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Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility.
Yu Jia Tan, Ming Li, Gregory Adrian Gunawan, Samuel Agyei Nyantakyi, Thomas Dick, Mei-Lin Go

ACS Med Chem Lett· May 2021

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Effects of Antimalarial Drugs on Neuroinflammation-Potential Use for Treatment of COVID-19-Related Neurologic Complications.
Wei-Yi Ong, Mei-Lin Go, De-Yun Wang, Irwin Kee-Mun Cheah, Barry Halliwell

Mol Neurobiol· January 2021

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Resistance against Membrane-Inserting MmpL3 Inhibitor through Upregulation of MmpL5 in Mycobacterium tuberculosis.
Ming Li, Samuel Agyei Nyantakyi, Mei-Lin Go, Thomas Dick

Antimicrob Agents Chemother· November 2020

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Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition.
Ming Li, Zheng Yen Phua, Yu Xi, Zhujun Xu, Samuel A Nyantakyi, Mei Lin Go

ACS Infect Dis· July 2020

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Extreme Drug Tolerance of "Persisters".
Yee-Kuen Yam, Nadine Alvarez, Mei-Lin Go, Thomas Dick

Front Microbiol· March 2020

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Rifabutin Suppresses Inducible Clarithromycin Resistance in by Blocking Induction of and .
Dinah Binte Aziz, Mei Lin Go, Thomas Dick

Antibiotics (Basel)· February 2020

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Antimalarial , -Dialkyldioxonaphthoimidazoliums: Synthesis, Biological Activity, and Structure-activity Relationships.
Stephen Ahenkorah, Dina Coertzen, Jie Xin Tong, Kevin Fridianto, Sergio Wittlin, Mei-Lin Go

ACS Med Chem Lett· January 2020

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Galloyl esters of trans-stilbenes are inhibitors of FASN with anticancer activity on non-small cell lung cancer cells.
Yu-Jia Tan, Azhar Ali, Sheng-Yang Tee, Jun-Ting Teo, Yu Xi, Mei-Lin Go

Eur J Med Chem· November 2019

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Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in .
Dereje Abate Negatu, Yoshiyuki Yamada, Yu Xi, Mei Lin Go, Matthew Zimmerman

mBio· March 2019

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Indolyl Azaspiroketal Mannich Bases Are Potent Antimycobacterial Agents with Selective Membrane Permeabilizing Effects and in Vivo Activity.
Samuel Agyei Nyantakyi, Ming Li, Pooja Gopal, Matthew Zimmerman, Véronique Dartois, Mei-Lin Go

J Med Chem· July 2018

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Anti-survivin effect of the small molecule inhibitor YM155 in RCC cells is mediated by time-dependent inhibition of the NF-κB pathway.
Mei Yi Sim, John Shyi Peng Yuen, Mei Lin Go

Sci Rep· July 2018

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The mechanistic effects of the dioxonaphthoimidazolium analog YM155 in renal cell carcinoma cell cycling and apoptosis.
Mei Yi Sim, Mei Lin Go, John Shyi Peng Yuen

Life Sci· June 2018

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Curcuminoids as EBV Lytic Activators for Adjuvant Treatment in EBV-Positive Carcinomas.
Octavia Ramayanti, Mitch Brinkkemper, Sandra A W M Verkuijlen, Leni Ritmaleni, Mei Lin Go

Cancers (Basel)· March 2018

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Indolylalkyltriphenylphosphonium Analogues Are Membrane-Depolarizing Mycobactericidal Agents.
Ming Li, Samuel A Nyantakyi, Pooja Gopal, Dinah Binte Aziz, Thomas Dick, Mei-Lin Go

ACS Med Chem Lett· November 2017

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A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A.
Cheng Yang Ng, Srinivasaraghavan Kannan, Yong Jun Chen, Francis Chee Kuan Tan, Wee Yong Ong, Mei Lin Go

Sci Rep· October 2017

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