Publications by authors named "Anne B Need"

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Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.
Kevin M Gardinier, Douglas L Gernert, Warren J Porter, Jon K Reel, Paul L Ornstein, Anne B Need

J Med Chem· May 2016

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Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human.
Linda M Rorick-Kehn, Jennifer W Witcher, Stephen L Lowe, Celedon R Gonzales, Mary Ann Weller, Anne B Need

Int J Neuropsychopharmacol· October 2014

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Glucose metabolic trapping in mouse arteries: nonradioactive assay of atherosclerotic plaque inflammation applicable to drug discovery.
Richard G Conway, Eyassu Chernet, David C De Rosa, Robert J Benschop, Anne B Need

PLoS One· June 2013

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In vivo rat brain opioid receptor binding of LY255582 assessed with a novel method using LC/MS/MS and the administration of three tracers simultaneously.
Anne B Need, Jamie H McKinzie, Charles H Mitch, Michael A Statnick, Lee A Phebus

Life Sci· October 2007

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Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: evidence for synergism between serotonergic and noradrenergic reuptake inhibition.
Carrie K Jones, Brian J Eastwood, Anne B Need, Harlan E Shannon

Neuropharmacology· December 2006

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Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice.
Xia Li, Anne B Need, Melvyn Baez, Jeffrey M Witkin

J Pharmacol Exp Ther· October 2006

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Comparison of rat dopamine D2 receptor occupancy for a series of antipsychotic drugs measured using radiolabeled or nonlabeled raclopride tracer.
Vanessa N Barth, Eyassu Chernet, Laura J Martin, Anne B Need, Karen S Rash

Life Sci· May 2006

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The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats.
Anne B Need, Richard J Davis, Jesline T Alexander-Chacko, Brian Eastwood, Eyassu Chernet

Psychopharmacology (Berl)· January 2006

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Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: dopamine D2, serotonin 2A and NK-1 receptors as examples.
Eyassu Chernet, Laura J Martin, Dominic Li, Anne B Need, Vanessa N Barth

Life Sci· December 2005

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Enhancement of antidepressant potency by a potentiator of AMPA receptors.
Xia Li, Jeffrey M Witkin, Anne B Need, Phil Skolnick

Cell Mol Neurobiol· June 2003

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