Publications by authors named "Anne Bertolotti"

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Termination of the integrated stress response.
Claudia De Miguel, Sigurdur R Thorkelsson, Agnieszka Fatalska, George Hodgson, Chao Wang, Anne Bertolotti

Science· November 2025

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Integrated stress response activator halofuginone protects mice from diabetes-like phenotypes.
Shashank Rai, Maria Szaruga, Aleksandra P Pitera, Anne Bertolotti

J Cell Biol· October 2024

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Keeping goblet cells unstressed: new insights into a general principle.
Anne Bertolotti

EMBO J· March 2024

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Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B.
Agnieszka Fatalska, George Hodgson, Stefan M V Freund, Sarah L Maslen, Tomos Morgan, Anne Bertolotti

Mol Cell· February 2024

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Activation of the integrated stress response by inhibitors of its kinases.
Maria Szaruga, Dino A Janssen, Claudia de Miguel, George Hodgson, Agnieszka Fatalska, Anne Bertolotti

Nat Commun· September 2023

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Cellular responses to halofuginone reveal a vulnerability of the GCN2 branch of the integrated stress response.
Aleksandra P Pitera, Maria Szaruga, Sew-Yeu Peak-Chew, Steven W Wingett, Anne Bertolotti

EMBO J· June 2022

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An Overview of Methods for Detecting eIF2α Phosphorylation and the Integrated Stress Response.
Agnieszka Krzyzosiak, Aleksandra P Pitera, Anne Bertolotti

Methods Mol Biol· February 2022

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Substrate recognition determinants of human eIF2α phosphatases.
George Hodgson, Antonina Andreeva, Anne Bertolotti

Open Biol· December 2021

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Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation.
Kim Schneider, Geoffrey Michael Nelson, Joseph Luke Watson, Jörg Morf, Maximillian Dalglish, Anne Bertolotti

Cell Rep· September 2020

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Potential benefit of manipulating protein quality control systems in neurodegenerative diseases.
Laura M Luh, Anne Bertolotti

Curr Opin Neurobiol· April 2020

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The split protein phosphatase system.
Anne Bertolotti

Biochem J· December 2018

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Regulation of proteasome assembly and activity in health and disease.
Adrien Rousseau, Anne Bertolotti

Nat Rev Mol Cell Biol· November 2018

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Importance of the subcellular location of protein deposits in neurodegenerative diseases.
Anne Bertolotti

Curr Opin Neurobiol· August 2018

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Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B.
Agnieszka Krzyzosiak, Anna Sigurdardottir, Laura Luh, Marta Carrara, Indrajit Das, Anne Bertolotti

Cell· August 2018

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Prion-like protein aggregates exploit the RHO GTPase to cofilin-1 signaling pathway to enter cells.
Zhen Zhong, Laura Grasso, Caroline Sibilla, Tim J Stevens, Nicholas Barry, Anne Bertolotti

EMBO J· March 2018

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Prion Properties of SOD1 in Amyotrophic Lateral Sclerosis and Potential Therapy.
Caroline Sibilla, Anne Bertolotti

Cold Spring Harb Perspect Biol· October 2017

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Coping with Protein Quality Control Failure.
Esther Pilla, Kim Schneider, Anne Bertolotti

Annu Rev Cell Dev Biol· October 2017

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Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors.
Marta Carrara, Anna Sigurdardottir, Anne Bertolotti

Nat Struct Mol Biol· September 2017

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qMotor, a set of rules for sensitive, robust and quantitative measurement of motor performance in mice.
Laura M Luh, Indrajit Das, Anne Bertolotti

Nat Protoc· July 2017

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Anne Bertolotti

Autophagy· October 2016

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Decoding the Protein Destruction Code: A Panoramic View.
Esther Pilla, Anne Bertolotti

Mol Cell· September 2016

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An evolutionarily conserved pathway controls proteasome homeostasis.
Adrien Rousseau, Anne Bertolotti

Nature· August 2016

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Surviving protein quality control catastrophes--from cells to organisms.
Kim Schneider, Anne Bertolotti

J Cell Sci· November 2015

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Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit.
Indrajit Das, Agnieszka Krzyzosiak, Kim Schneider, Lawrence Wrabetz, Maurizio D'Antonio, Anne Bertolotti

Science· April 2015

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An inducible chaperone adapts proteasome assembly to stress.
Ariane Hanssum, Zhen Zhong, Adrien Rousseau, Agnieszka Krzyzosiak, Anna Sigurdardottir, Anne Bertolotti

Mol Cell· August 2014

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