Publications by authors named "Maria Szaruga"

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Integrated stress response activator halofuginone protects mice from diabetes-like phenotypes.
Shashank Rai, Maria Szaruga, Aleksandra P Pitera, Anne Bertolotti

J Cell Biol· October 2024

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Activation of the integrated stress response by inhibitors of its kinases.
Maria Szaruga, Dino A Janssen, Claudia de Miguel, George Hodgson, Agnieszka Fatalska

Nat Commun· September 2023

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Aβ profiles generated by Alzheimer's disease causing PSEN1 variants determine the pathogenicity of the mutation and predict age at disease onset.
Dieter Petit, Sara Gutiérrez Fernández, Katarzyna Marta Zoltowska, Thomas Enzlein, Natalie S Ryan, Maria Szaruga

Mol Psychiatry· June 2022

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Cellular responses to halofuginone reveal a vulnerability of the GCN2 branch of the integrated stress response.
Aleksandra P Pitera, Maria Szaruga, Sew-Yeu Peak-Chew, Steven W Wingett, Anne Bertolotti

EMBO J· June 2022

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Spastic paraplegia preceding -related familial Alzheimer's disease.
Viorica Chelban, Marianthi Breza, Maria Szaruga, Jana Vandrovcova, David Murphy

Alzheimers Dement (Amst)· May 2021

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Alzheimer's-causing mutations shift Aβ length by destabilizing γ-secretase-Aβn interactions.
Maria Szaruga, Bogdan Munteanu, Sam Lismont, Sarah Veugelen, Katrien Horré

Cell· April 2021

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Prodromal Alzheimer's Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer's Pathology.
Silvia de Vidania, Irene Palomares-Perez, Ana Frank-García, Takashi Saito, Takaomi C Saido, María Szaruga

Front Neurosci· December 2020

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Mechanisms of neurodegeneration - Insights from familial Alzheimer's disease.
Lucía Chávez-Gutiérrez, Maria Szaruga

Semin Cell Dev Biol· September 2020

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Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP.
Frances K Wiseman, Laura J Pulford, Chris Barkus, Fan Liao, Erik Portelius, Maria Szaruga

Brain· August 2018

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Deletion of exons 9 and 10 of the Presenilin 1 gene in a patient with Early-onset Alzheimer Disease generates longer amyloid seeds.
Kilan Le Guennec, Sarah Veugelen, Olivier Quenez, Maria Szaruga, Stéphane Rousseau

Neurobiol Dis· August 2017

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Alzheimer's-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions.
Maria Szaruga, Bogdan Munteanu, Sam Lismont, Sarah Veugelen, Katrien Horré

Cell· July 2017

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Qualitative changes in human γ-secretase underlie familial Alzheimer's disease.
Maria Szaruga, Sarah Veugelen, Manasi Benurwar, Sam Lismont, Diego Sepulveda-Falla

J Exp Med· November 2015

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