Publications by authors named "Anne Cheasty"

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Correction to "Discovery of a Thiadiazole-Pyridazine-Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models".
M Raymond V Finlay, Mark Anderton, Andrew Bailey, Scott Boyd, Joanna Brookfield, Anne Cheasty

J Med Chem· July 2023

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Establishing the selective phospholipid membrane coordination, permeation and lysis properties for a series of 'druggable' supramolecular self-associating antimicrobial amphiphiles.
Jessica E Boles, Charlotte Bennett, Jennifer Baker, Kira L F Hilton, Hiral A Kotak, Anne Cheasty

Chem Sci· August 2022

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MNK Inhibition Sensitizes -Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression.
John R P Knight, Constantinos Alexandrou, George L Skalka, Nikola Vlahov, Kathryn Pennel, Anne Cheasty

Cancer Discov· May 2021

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Discovery of a Thiadiazole-Pyridazine-Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models.
M Raymond V Finlay, Mark Anderton, Andrew Bailey, Scott Boyd, Joanna Brookfield, Anne Cheasty

J Med Chem· July 2019

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Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins.
Niall Igoe, Elliott D Bayle, Cynthia Tallant, Oleg Fedorov, Julia C Meier, Anne Cheasty

J Med Chem· August 2017

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Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies.
Niall Igoe, Elliott D Bayle, Oleg Fedorov, Cynthia Tallant, Pavel Savitsky, Anne Cheasty

J Med Chem· January 2017

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Discovery of potent inhibitors of the lysophospholipase autotaxin.
Pritom Shah, Anne Cheasty, Caroline Foxton, Tony Raynham, Muddasar Farooq

Bioorg Med Chem Lett· November 2016

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Discovery, Development, and SAR of Aminothiazoles as LIMK Inhibitors with Cellular Anti-Invasive Properties.
Mark D Charles, Joanna L Brookfield, Tennyson C Ekwuru, Martin Stockley, John Dunn, Anne Cheasty

J Med Chem· October 2015

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Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate.
Martin J Slater, Elizabeth M Amphlett, David M Andrews, Gianpaolo Bravi, George Burton, Anne G Cheasty

J Med Chem· March 2007

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