Publications by authors named "Tony Raynham"

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Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
Andrew P Turnbull, Stephanos Ioannidis, Wojciech W Krajewski, Adan Pinto-Fernandez, Claire Heride, Tony M Raynham

Nature· October 2017

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Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication.
Anabel Guedán, Dawid Swieboda, Mark Charles, Marie Toussaint, Sebastian L Johnston, Tony Raynham

J Virol· May 2017

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Discovery of potent inhibitors of the lysophospholipase autotaxin.
Pritom Shah, Anne Cheasty, Caroline Foxton, Tony Raynham, Muddasar Farooq

Bioorg Med Chem Lett· November 2016

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Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3).
Jack U Flanagan, Graham J Atwell, Daniel M Heinrich, Darby G Brooke, Shevan Silva, Tony Raynham

Bioorg Med Chem· February 2014

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Protein kinase D2 regulates migration and invasion of U87MG glioblastoma cells in vitro.
Eva Bernhart, Sabine Damm, Andrea Wintersperger, Trevor DeVaney, Andreas Zimmer, Tony Raynham

Exp Cell Res· August 2013

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Synthesis and structure-activity relationships for 1-(4-(piperidin-1-ylsulfonyl)phenyl)pyrrolidin-2-ones as novel non-carboxylate inhibitors of the aldo-keto reductase enzyme AKR1C3.
Daniel M Heinrich, Jack U Flanagan, Stephen M F Jamieson, Shevan Silva, Laurent J M Rigoreau, Tony Raynham

Eur J Med Chem· April 2013

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3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3.
Stephen M F Jamieson, Darby G Brooke, Daniel Heinrich, Graham J Atwell, Shevan Silva, Tony Raynham

J Med Chem· September 2012

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Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2.
John J Caldwell, Emma J Welsh, Cornelis Matijssen, Victoria E Anderson, Laurent Antoni, Tony Raynham

J Med Chem· January 2011

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Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells.
Ian M Evans, Azadeh Bagherzadeh, Mark Charles, Tony Raynham, Chris Ireson

Biochem J· August 2010

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A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo.
Kuzhuvelil B Harikumar, Ajaikumar B Kunnumakkara, Nobuo Ochi, Zhimin Tong, Amit Deorukhkar, Tony Raynham

Mol Cancer Ther· May 2010

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Preparation of kinase-biased compounds in the search for lead inhibitors of kinase targets.
Justine Y Q Lai, Steven Langston, Ruth Adams, Rebekah E Beevers, Richard Boyce, Tony Raynham

Med Res Rev· May 2005

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Enantiomerically pure alpha-amino acid synthesis via hydroboration-suzuki cross-coupling.
Philip N Collier, Andrew D Campbell, Ian Patel, Tony M Raynham, Richard J K Taylor

J Org Chem· March 2002

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Solution and solid-phase synthesis of potent inhibitors of hepatitis C virus NS3 proteinase.
Rebekah Beevers, Maria G Carr, Philip S Jones, Steven Jordan, Paul B Kay, Tony M Raynham

Bioorg Med Chem Lett· February 2002

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