Publications by authors named "Mark Charles"

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C
Correction to "Discovery of a Thiadiazole-Pyridazine-Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models".
M Raymond V Finlay, Mark Anderton, Andrew Bailey, Scott Boyd, Joanna Brookfield, Mark Charles

J Med Chem· July 2023

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Correction to "Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta".
Martin L Stockley, Giovanni Benedetti, Peter Blencowe, Simon J Boulton, Susan M Boyd, Mark D Charles

J Med Chem· February 2023

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Rapid Development of Cell State Identification Circuits with Poly-Transfection.
Noreen Wauford, Ross Jones, Charles Van De Mark, Ron Weiss

J Vis Exp· February 2023

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Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.
Martin L Stockley, Amanda Ferdinand, Giovanni Benedetti, Peter Blencowe, Susan M Boyd, Mark D Charles

J Med Chem· October 2022

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Establishing the selective phospholipid membrane coordination, permeation and lysis properties for a series of 'druggable' supramolecular self-associating antimicrobial amphiphiles.
Jessica E Boles, Charlotte Bennett, Jennifer Baker, Kira L F Hilton, Hiral A Kotak, Mark Charles

Chem Sci· August 2022

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Genetic Variants in Interleukin-10 Gene Association with Susceptibility and Cervical Cancer Development: A Case Control Study.
Pushpendra D Pratap, Syed Tasleem Raza, Ghazala Zaidi, Shipra Kunwar, Sharique Ahmad, Mark Rector Charles

Glob Med Genet· June 2022

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Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
Diana Zatreanu, Helen M R Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Mark Charles

Nat Commun· June 2021

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Cytokine Storm and Mucus Hypersecretion in COVID-19: Review of Mechanisms.
Mohsin Ali Khan, Zaw Ali Khan, Mark Charles, Pushpendra Pratap, Abdul Naeem

J Inflamm Res· January 2021

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Association of DNA Repair Genes XRCC1 and APE-1 with the Risk of Cervical Cancer in North Indian population.
Mark Rector Charles, Syed Tasleem Raza, Rolee Sharma, Pushpendra Pratap, Ale Eba

Asian Pac J Cancer Prev· July 2020

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Identifying strategies to target the metabolic flexibility of tumours.
Andrés Méndez-Lucas, Wei Lin, Paul C Driscoll, Nathalie Legrave, Laura Novellasdemunt, Mark Charles

Nat Metab· April 2020

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Discovery of a Thiadiazole-Pyridazine-Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models.
M Raymond V Finlay, Mark Anderton, Andrew Bailey, Scott Boyd, Joanna Brookfield, Mark Charles

J Med Chem· July 2019

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Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication.
Anabel Guedán, Dawid Swieboda, Mark Charles, Marie Toussaint, Sebastian L Johnston

J Virol· May 2017

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LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation.
Katerina Mardilovich, Mark Baugh, Diane Crighton, Dominika Kowalczyk, Mads Gabrielsen, Mark Charles

Oncotarget· November 2015

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Discovery, Development, and SAR of Aminothiazoles as LIMK Inhibitors with Cellular Anti-Invasive Properties.
Mark D Charles, Joanna L Brookfield, Tennyson C Ekwuru, Martin Stockley, John Dunn

J Med Chem· October 2015

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Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells.
Ian M Evans, Azadeh Bagherzadeh, Mark Charles, Tony Raynham, Chris Ireson

Biochem J· August 2010

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A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo.
Kuzhuvelil B Harikumar, Ajaikumar B Kunnumakkara, Nobuo Ochi, Zhimin Tong, Amit Deorukhkar, Mark Charles

Mol Cancer Ther· May 2010

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Efficient pd-catalyzed amination of heteroaryl halides.
Mark D Charles, Phillip Schultz, Stephen L Buchwald

Org Lett· September 2005

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Soft-tissue balancing of the hip: the role of femoral offset restoration.
Mark N Charles, Robert B Bourne, J Roderick Davey, A Seth Greenwald, Bernard F Morrey

Instr Course Lect· June 2005

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