Publications by authors named "Steven Jordan"

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Translating theory into clinical practice: a qualitative study of clinician perspectives implementing whole person care.
Philip Leger, Valerie Caldas, Carolina Festa, Tom Hutchinson, Steven Jordan

BMJ Open Qual· July 2023

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Quadriceps Tendon Repair Using Double-Row Suture Anchor Fixation.
Joseph S Tramer, Hardy Evans, Alexander C Ziedas, Alexander J Swantek, Steven E Jordan

Arthrosc Tech· October 2021

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Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase-Glucokinase Regulatory Protein (GK-GKRP) Binding: Strategic Use of a N → S (nN → σ*S-X) Interaction for Conformational Constraint.
Lewis D Pennington, Michael D Bartberger, Michael D Croghan, Kristin L Andrews, Kate S Ashton, Steven R Jordan

J Med Chem· December 2015

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Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis.
Nuria A Tamayo, Mark H Norman, Michael D Bartberger, Fang-Tsao Hong, Yunxin Bo, Steven R Jordan

J Med Chem· June 2015

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Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 4. Exploration of a novel binding pocket.
Fang-Tsao Hong, Mark H Norman, Kate S Ashton, Michael D Bartberger, Jie Chen, Steven R Jordan

J Med Chem· July 2014

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Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine series.
Nobuko Nishimura, Mark H Norman, Longbin Liu, Kevin C Yang, Kate S Ashton, Steven R Jordan

J Med Chem· April 2014

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Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles.
David J St Jean, Kate S Ashton, Michael D Bartberger, Jie Chen, Samer Chmait, Steven R Jordan

J Med Chem· January 2014

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Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.
David J Lloyd, David J St Jean, Robert J M Kurzeja, Robert C Wahl, Klaus Michelsen, Steven R Jordan

Nature· December 2013

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Hydroxyethylamine-based inhibitors of BACE1: P₁-P₃ macrocyclization can improve potency, selectivity, and cell activity.
Lewis D Pennington, Douglas A Whittington, Michael D Bartberger, Steven R Jordan, Holger Monenschein

Bioorg Med Chem Lett· August 2013

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A hybrid structural approach to analyze ligand binding by the serotonin type 4 receptor (5-HT4).
Pius S Padayatti, Liwen Wang, Sayan Gupta, Tivadar Orban, Wenyu Sun, Steven R Jordan

Mol Cell Proteomics· May 2013

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Post-translational modifications of the serotonin type 4 receptor heterologously expressed in mouse rod cells.
David Salom, Benlian Wang, Zhiqian Dong, Wenyu Sun, Pius Padayatti, Steven Jordan

Biochemistry· January 2012

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Discovery of a potent, orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor for clinical study: identification of (S)-2-((1S,2S,4R)-bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221).
Murielle M Véniant, Clarence Hale, Randall W Hungate, Kyung Gahm, Maurice G Emery, Steven Jordan

J Med Chem· June 2010

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Heterologous expression and purification of the serotonin type 4 receptor from transgenic mouse retina.
David Salom, Nan Wu, Wenyu Sun, Zhiqian Dong, Krzysztof Palczewski, Steven Jordan

Biochemistry· December 2008

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2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice.
Lars Johansson, Christopher Fotsch, Michael D Bartberger, Victor M Castro, Michelle Chen, Steven R Jordan

J Med Chem· May 2008

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The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.
Chester Yuan, David J St Jean, Qingyian Liu, Lynn Cai, Aiwen Li, Steven Jordan

Bioorg Med Chem Lett· November 2007

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Heterologous expression of the adenosine A1 receptor in transgenic mouse retina.
Ning Li, David Salom, Li Zhang, Tim Harris, Juan A Ballesteros, Steven Jordan

Biochemistry· July 2007

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Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).
Michael A McDonough, Vivian Li, Emily Flashman, Rasheduzzaman Chowdhury, Christopher Mohr, Steven Jordan

Proc Natl Acad Sci U S A· June 2006

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Crystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetes.
Jiandong Zhang, Timothy D Osslund, Matthew H Plant, Christi L Clogston, Rebecca E Nybo, Steven R Jordan

Biochemistry· May 2005

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(4-Piperidinylphenyl)aminoethyl amides as a novel class of non-covalent cathepsin K inhibitors.
Tae-Seong Kim, Andrew B Hague, Tony I Lee, Brian Lian, Christopher M Tegley, Steven Jordan

Bioorg Med Chem Lett· January 2004

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A microprobe study of element distribution in vaginal epithelial cells of the rat.
Hubert R Catchpole, Milton B Engel, Steven L Jordan

Cell Biol Int· December 2003

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Solution and solid-phase synthesis of potent inhibitors of hepatitis C virus NS3 proteinase.
Rebekah Beevers, Maria G Carr, Philip S Jones, Steven Jordan, Paul B Kay

Bioorg Med Chem Lett· February 2002

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