Publications by authors named "Anne Filppula"

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Automated 3D printing of pediatric furosemide tablets: A personalized medicine approach using semi-solid extrusion and NIR monitoring.
Farnaz Shokraneh, Anne M Filppula, Aleksi Tornio, Jaan Aruväli, Urve Paaver

Eur J Pharm Sci· November 2025

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Mechanically regulated microcarriers with stem cell loading for skin photoaging therapy.
Xiang Lin, Anne M Filppula, Yuanjin Zhao, Luoran Shang, Hongbo Zhang

Bioact Mater· April 2025

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Dual physiological responsive structural color hydrogel particles for wound repair.
Li Wang, Lu Fan, Anne M Filppula, Yu Wang, Feika Bian

Bioact Mater· April 2025

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Biomineralize Mitochondria in Metal-Organic Frameworks to Promote Mitochondria Transplantation From Non-Tumorigenic Cells Into Cancer Cells.
Jun-Nian Zhou, Chang Liu, Yonghui Wang, Yong Guo, Xiao-Yu Xu, Anne M Filppula

Smart Med· March 2025

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Automated extrusion-based dispensing: Personalized dosing and quality control of clopidogrel tablets for pediatric care.
Farnaz Shokraneh, Anne M Filppula, Aleksi Tornio, Jaan Aruväli, Urve Paaver

Eur J Pharm Sci· January 2025

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Encapsulated mitochondria to reprogram the metabolism of M2-type macrophages for anti-tumor therapy.
Yonghui Wang, Chang Liu, Xiaodong Ma, Anne Filppula, Youbin Cui

Nanoscale· November 2024

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Candesartan Has No Clinically Meaningful Effect on the Plasma Concentrations of Cytochrome P450 2C8 Substrate Repaglinide in Humans.
Mikael O W Piha, Kristiina Cajanus, Marica T Engström, Mikko Neuvonen, Troels K Bergmann, Anne M Filppula

Drug Metab Dispos· November 2024

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Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes - detailed studies on CYP3A inhibitors.
Helinä Kahma, Marie-Noëlle Paludetto, Mikko Neuvonen, Mika Kurkela, Anne M Filppula

Eur J Pharm Sci· July 2024

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Self-Healing Dynamic Hydrogel Microparticles with Structural Color for Wound Management.
Li Wang, Xiaoya Ding, Lu Fan, Anne M Filppula, Qinyu Li

Nanomicro Lett· July 2024

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Solanidine is a sensitive and specific dietary biomarker for CYP2D6 activity.
Johanna I Kiiski, Mikko Neuvonen, Mika Kurkela, Päivi Hirvensalo, Kreetta Hämäläinen, Anne M Filppula

Hum Genomics· February 2024

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Ticagrelor Increases Exposure to the Breast Cancer Resistance Protein Substrate Rosuvastatin.
Minna Lehtisalo, E Katriina Tarkiainen, Mikko Neuvonen, Mikko Holmberg, Johanna I Kiiski, Anne M Filppula

Clin Pharmacol Ther· January 2024

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Real-world pharmacogenetics of statin intolerance: effects of SLCO1B1, ABCG2 , and CYP2C9 variants.
K Ivar Lönnberg, Aleksi Tornio, Päivi Hirvensalo, Jenni Keskitalo, Anna-Liina Mustaniemi, Anne M Filppula

Pharmacogenet Genomics· September 2023

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Fabricating biomimetic materials with ice-templating for biomedical applications.
Xiang Lin, Lu Fan, Li Wang, Anne M Filppula, Yunru Yu

Smart Med· August 2023

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Rhabdomyolysis during concomitant ticagrelor and rosuvastatin: A breast cancer resistance protein-mediated drug interaction?
Minna Lehtisalo, Wilma Kiander, Anne M Filppula, Feng Deng, Heidi Kidron

Br J Clin Pharmacol· July 2023

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Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A .
Marie-Noëlle Paludetto, Mika Kurkela, Helinä Kahma, Janne T Backman, Mikko Niemi, Anne M Filppula

Drug Metab Dispos· March 2023

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Translational aspects of cytochrome P450-mediated drug-drug interactions: A case study with clopidogrel.
Aleksi Tornio, Anne M Filppula, Janne T Backman

Basic Clin Pharmacol Toxicol· January 2022

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Comparative Hepatic and Intestinal Efflux Transport of Statins.
Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Anne M Filppula

Drug Metab Dispos· September 2021

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Comparative Hepatic and Intestinal Metabolism and Pharmacodynamics of Statins.
Anne M Filppula, Päivi Hirvensalo, Heli Parviainen, Vilma E Ivaska, K Ivar Lönnberg

Drug Metab Dispos· August 2021

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An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes - application to establishing CYP2C8 inhibitor selectivity.
Helinä Kahma, Laura Aurinsalo, Mikko Neuvonen, Jani Katajamäki, Marie-Noëlle Paludetto, Anne M Filppula

Eur J Pharm Sci· July 2021

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Clinical Studies on Drug-Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation.
Aleksi Tornio, Anne M Filppula, Mikko Niemi, Janne T Backman

Clin Pharmacol Ther· June 2019

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Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8.
Helinä Kahma, Anne M Filppula, Terhi Launiainen, Jenni Viinamäki, Mikko Neuvonen

Drug Metab Dispos· April 2019

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Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations.
Anne M Filppula, Rezvan Parvizi, André Mateus, Pawel Baranczewski, Per Artursson

Sci Rep· April 2019

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In Vitro Screening of Six Protein Kinase Inhibitors for Time-Dependent Inhibition of CYP2C8 and CYP3A4: Possible Implications with regard to Drug-Drug Interactions.
Anne M Filppula, Tiffany M Mustonen, Janne T Backman

Basic Clin Pharmacol Toxicol· December 2018

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Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8-Mediated Metabolism of Montelukast in Humans.
Matti K Itkonen, Aleksi Tornio, Anne M Filppula, Mikko Neuvonen, Pertti J Neuvonen

Clin Pharmacol Ther· September 2018

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Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions.
Helinä Kahma, Anne M Filppula, Mikko Neuvonen, E Katriina Tarkiainen, Aleksi Tornio

Drug Metab Dispos· February 2018

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