Publications by authors named "Anne Fourie"

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A transgenic mouse allows characterisation of the HLA-C*06:02 immunopeptidome in a model of psoriasis.
Asolina Braun, Jesse I Mobbs, Shanzou Chung, Johanna E Tuomisto, Chen Li, Anne Fourie

J Invest Dermatol· December 2025

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Translational Pharmacokinetics of Icotrokinra, a Targeted Oral Peptide that Selectively Blocks Interleukin-23 Receptor and Inhibits Signaling.
Beverly Knight, Brinda Tammara, Nishit B Modi, Shannon Dallas, Saro Mardirosian, Anne Fourie

Dermatol Ther (Heidelb)· September 2025

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Guselkumab binding to CD64 IL-23-producing myeloid cells enhances potency for neutralizing IL-23 signaling.
Kacey L Sachen, Deepa Hammaker, Indra Sarabia, Brian Stoveken, John Hartman, Anne M Fourie

Front Immunol· May 2025

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Identification of JNJ-61803534, a RORγt Inverse Agonist for the Treatment of Psoriasis.
Olaf Kinzel, Steven D Goldberg, Maxwell D Cummings, Christian Gege, Christoph Steeneck, Anne M Fourie

J Med Chem· April 2025

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IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells.
Laetitia Camard, Tharshana Stephen, Hanane Yahia-Cherbal, Vincent Guillemot, Sébastien Mella, Anne M Fourie

iScience· February 2025

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The mode of action of IL-23 in experimental inflammatory arthritic pain and disease.
Kevin M-C Lee, Tanya Lupancu, Leon Chang, Carl L Manthey, Martha Zeeman, Anne M Fourie

Arthritis Res Ther· August 2024

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IL-23 regulation of myeloid cell biology during inflammation.
Kevin M-C Lee, Tanya Lupancu, Leon Chang, Carl L Manthey, Martha Zeeman, Anne M Fourie

Cytokine· July 2024

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JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans.
Anne M Fourie, Xiaoli Cheng, Leon Chang, Carrie Greving, Xinyi Li

Sci Rep· July 2024

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IL-23 past, present, and future: a roadmap to advancing IL-23 science and therapy.
James G Krueger, Kilian Eyerich, Vijay K Kuchroo, Christopher T Ritchlin, Maria T Abreu, Anne Fourie

Front Immunol· April 2024

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Author Correction: Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534.
Xiaohua Xue, Aimee De Leon-Tabaldo, Rosa Luna-Roman, Glenda Castro, Michael Albers, Anne M Fourie

Sci Rep· April 2022

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Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8 T cells in autoimmunity and cancer.
Jared Liu, Hsin-Wen Chang, Zhi-Ming Huang, Mio Nakamura, Sahil Sekhon, Anne M Fourie

J Allergy Clin Immunol· June 2021

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Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534.
Xiaohua Xue, Aimee De Leon-Tabaldo, Rosa Luna-Roman, Glenda Castro, Michael Albers, Anne M Fourie

Sci Rep· May 2021

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Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach.
Christoph Steeneck, Christian Gege, Olaf Kinzel, Michael Albers, Gerald Kleymann, Anne M Fourie

Bioorg Med Chem Lett· June 2020

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Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt.
Christian Gege, Michael Albers, Olaf Kinzel, Gerald Kleymann, Thomas Schlüter, Anne M Fourie

Bioorg Med Chem Lett· June 2020

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3-Substituted Quinolines as RORγt Inverse Agonists.
Virginia M Tanis, Hariharan Venkatesan, Maxwell D Cummings, Michael Albers, J Kent Barbay, Anne M Fourie

Bioorg Med Chem Lett· June 2019

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Identification and biological evaluation of thiazole-based inverse agonists of RORγt.
Christian Gege, Maxwell D Cummings, Michael Albers, Olaf Kinzel, Gerald Kleymann, Anne Fourie

Bioorg Med Chem Lett· May 2018

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6-Substituted quinolines as RORγt inverse agonists.
J Kent Barbay, Maxwell D Cummings, Marta Abad, Glenda Castro, Kevin D Kreutter, Anne M Fourie

Bioorg Med Chem Lett· December 2017

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RORγt and RORα signature genes in human Th17 cells.
Glenda Castro, Xuejun Liu, Karen Ngo, Aimee De Leon-Tabaldo, Shanrong Zhao, Anne Fourie

PLoS One· October 2017

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Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt.
David A Kummer, Maxwell D Cummings, Marta Abad, Joseph Barbay, Glenda Castro, Anne M Fourie

Bioorg Med Chem Lett· May 2017

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Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis.
Xiaohua Xue, Pejman Soroosh, Aimee De Leon-Tabaldo, Rosa Luna-Roman, Marciano Sablad, Anne M Fourie

Sci Rep· December 2016

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Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.
Pejman Soroosh, Jiejun Wu, Xiaohua Xue, Jiao Song, Steven W Sutton, Anne M Fourie

Proc Natl Acad Sci U S A· August 2014

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Quantitation of leukotriene B(4) in human sputum as a biomarker using UPLC-MS/MS.
Wenying Jian, Richard W Edom, Xiaohua Xue, Mike-Qingtao Huang, Anne Fourie

J Chromatogr B Analyt Technol Biomed Life Sci· August 2013

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A highly sensitive and selective method for the determination of leukotriene B4 (LTB4) in ex vivo stimulated human plasma by ultra fast liquid chromatography-tandem mass spectrometry.
Weisheng Lin, Mike-Qingtao Huang, Xiaohua Xue, Kirk Bertelsen, Guiyan Chen, Anne Fourie

J Chromatogr B Analyt Technol Biomed Life Sci· April 2013

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Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.
Wendy Eccles, Jonathan M Blevitt, Jamila N Booker, Christa C Chrovian, Shelby Crawford, Anne M Fourie

Bioorg Med Chem Lett· February 2013

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Azabenzthiazole inhibitors of leukotriene A₄ hydrolase.
Virginia M Tanis, Genesis M Bacani, Jonathan M Blevitt, Christa C Chrovian, Shelby Crawford, Anne M Fourie

Bioorg Med Chem Lett· December 2012

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