Publications by authors named "Anne Marie Api"

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Quantitative next generation risk assessment for skin sensitization - application of regression models based on in vitro data to estimate point of departure.
Isabelle Lee, Mihwa Na, Maura Lavelle, Isabella Schember, Marissa A Guttenberg, Anne Marie Api

Regul Toxicol Pharmacol· January 2026

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Updates to the Research Institute for Fragrance Materials, Inc. Confirmation of No Induction in Human Test Standard Protocol.
Maura Lavelle, Isabelle Lee, Devin O'Brien, Mihwa Na, Anne Marie Api

Dermatitis· September 2025

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Correction: Grouping of chemicals for safety assessment: the importance of toxicokinetic properties of salicylate esters.
Abdulkarim Najjar, Sébastien Grégoire, Beate Nicol, Andreas Natsch, Nazanin Golbamaki, Anne Marie Api

Arch Toxicol· June 2025

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The Chicken Egg Genotoxicity Assay (CEGA): Assessing Target Tissue Exposure and Metabolism in the Embryo-Fetal Chicken Livers.
Yax Thakkar, T Kobets, Anne Marie Api, J D Duan, G M Williams

Environ Mol Mutagen· June 2025

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Determining a point of departure for skin sensitization potency and quantitative risk assessment of fragrance ingredients using the GARDskin dose-response assay.
Isabelle Lee, Andy Forreryd, Mihwa Na, Isabella Schember, Maura Lavelle, Anne Marie Api

ALTEX· April 2025

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In vitro human skin absorption of ethyl salicylate, pentyl salicylate, and (Z)-3-hexenyl salicylate from topical formulations: Effects on permeation and distribution.
Kaushal Joshi, Darren M Green, A Christian Jones, Sophie E Davies, Sophie G Stocks, Anne Marie Api

Toxicol In Vitro· April 2025

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Grouping of chemicals for safety assessment: the importance of toxicokinetic properties of salicylate esters.
Abdulkarim Najjar, Sébastien Grégoire, Beate Nicol, Andreas Natsch, Nazanin Golbamaki, Anne Marie Api

Arch Toxicol· March 2025

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Incorporating Singaporean habits and practices for cosmetics and personal care products into a global consumer aggregate exposure model.
Siti Amelia Juraimi, Cesar Scrochi, Jonathan Lok, Anne Marie Api, Benjamin P C Smith

Regul Toxicol Pharmacol· February 2025

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A Proof-of-Concept for Safety Evaluation of Inhalation Exposure to Known Respiratory Irritants Using In Vitro and In Silico Methods.
Nikaeta Sadekar, Holger Peter Behrsing, Tanja Hansen, Vivek Patel, Hazel Paulo, Anne Marie Api

Toxics· January 2025

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Updating Reaction Mechanistic Domains for Skin Sensitization: 1. Nucleophilic Skin Sensitizers.
David W Roberts, Anne Marie Api, Aynur Aptula, Isabelle Lee, Holger Moustakas

Chem Res Toxicol· November 2024

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Predicting points of departure and potency categories for fragrance ingredients by integrating OECD in vitro models.
Isabelle Lee, Mihwa Na, Maura Lavelle, Isabella Schember, Cindy Ryan, Anne Marie Api

Food Chem Toxicol· November 2024

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Assessment of genotoxic potential of fragrance materials in the chicken egg assays.
Yax Thakkar, Tetyana Kobets, Anne Marie Api, Jian-Dong Duan, Gary M Williams

Environ Mol Mutagen· October 2024

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In vitro to in vivo extrapolation to derive a metabolism factor for estimating the aggregate exposure to salicylic acid after dermal exposure of its esters.
Abdulkarim Najjar, Sebastien Grégoire, Beate Nicol, Andreas Natsch, Nazanin Golbamaki, Anne Marie Api

Arch Toxicol· July 2024

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GARDskin dose-response assay and its application in conducting Quantitative Risk Assessment (QRA) for fragrance materials using a Next Generation Risk Assessment (NGRA) framework.
Shashikiran Donthamsetty, Andy Forreryd, Paul Sterchele, Xiao Huang, Robin Gradin, Anne Marie Api

Regul Toxicol Pharmacol· May 2024

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Detailed aggregate exposure analysis shows that exposure to fragrance ingredients in consumer products is low: Many orders of magnitude below thresholds of concern.
Isabelle Lee, Cesar Scrochi, Olive Chon, Mary Ann Cancellieri, Ambarnil Ghosh, Anne Marie Api

Regul Toxicol Pharmacol· March 2024

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Utility of ToxTracker in animal alternative testing strategy for fragrance materials.
Yax Thakkar, Holger Moustakas, Nynke Moelijker, Giel Hendriks, Inger Brandsma, Anne Marie Api

Environ Mol Mutagen· April 2023

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A Cautionary tale for using read-across for cancer hazard classification: Case study of isoeugenol and methyl eugenol.
Xiaoling Zhang, Susan P Felter, Anne Marie Api, Kaushal Joshi, Dan Selechnik

Regul Toxicol Pharmacol· December 2022

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An End Point-Specific Framework for Read-Across Analog Selection for Human Health Effects.
Holger Moustakas, Mihir S Date, Manoj Kumar, Terry W Schultz, Daniel C Liebler, Anne Marie Api

Chem Res Toxicol· December 2022

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Updating the Dermal Sensitisation Thresholds using an expanded dataset and an in silico expert system.
Martyn L Chilton, Anne Marie Api, Robert S Foster, G Frank Gerberick, Maura Lavelle

Regul Toxicol Pharmacol· August 2022

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Expansion of the Cosmetics Europe skin sensitisation database with new substances and PPRA data.
Sebastian Hoffmann, Nathalie Alépée, Nicola Gilmour, Petra S Kern, Erwin van Vliet, Anne Marie Api

Regul Toxicol Pharmacol· June 2022

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Benchmarking performance of SENS-IS assay against weight of evidence skin sensitization potency categories.
Mihwa Na, Devin O'Brien, G Frank Gerberick, Petra S Kern, Maura Lavelle, Anne Marie Api

Regul Toxicol Pharmacol· April 2022

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The BlueScreen HC assay to predict the genotoxic potential of fragrance materials.
Yax Thakkar, Kaushal Joshi, Christina Hickey, Joseph Wahler, Brian Wall, Anne Marie Api

Mutagenesis· April 2022

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Weight of Evidence Approach for Skin Sensitization Potency Categorization of Fragrance Ingredients.
Mihwa Na, Devin O'Brien, Maura Lavelle, Isabelle Lee, G Frank Gerberick, Anne Marie Api

Dermatitis· March 2022

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Implementation of a dermal sensitization threshold (DST) concept for risk assessment: structure-based DST and data-based DST.
Taku Nishijo, Anne Marie Api, G Frank Gerberick, Masaaki Miyazawa, Mihwa Na

Crit Rev Toxicol· January 2022

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Identifying a reference list of respiratory sensitizers for the evaluation of novel approaches to study respiratory sensitization.
Nikaeta Sadekar, Fanny Boisleve, Wolfgang Dekant, Allison D Fryer, G Frank Gerberick, Anne Marie Api

Crit Rev Toxicol· November 2021

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