Publications by authors named "Isabelle Lee"

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Quantitative next generation risk assessment for skin sensitization - application of regression models based on in vitro data to estimate point of departure.
Isabelle Lee, Mihwa Na, Maura Lavelle, Isabella Schember, Marissa A Guttenberg

Regul Toxicol Pharmacol· January 2026

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Prediction of the risk of diabetic foot from corneal nerve images using deep learning algorithms.
Chang Liu, Lei Zhu, Gavin Patrick O'Donnell, Mui Hui Koh, Mingyi Yu, Isabelle Xin Yu Lee

Diabetes Res Clin Pract· December 2025

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One-Year Tear Proteomic Alterations with Topical Cyclosporine-A 0.1% Emulsion in Patients with Allogeneic Stem Cell Transplant.
Chang Liu, Xinyue Wang, Sharon Wan Jie Yeo, Isabelle Xin Yu Lee, Yeh Ching Linn

Transplant Cell Ther· November 2025

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Ethnic and sex differences in corneal nerves and corneal epithelial cells in healthy population.
Fengyi Liu, Chang Liu, Mingyi Yu, Isabelle Xin Yu Lee, Hassan Mansoor

Front Med (Lausanne)· November 2025

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Fenofibrate ameliorates ocular surface inflammation in diabetic keratopathy.
Hassan Mansoor, Isabelle Xin Yu Lee, Chang Liu, Mingyi Yu, Charmaine Jan Li Toh

Ocul Surf· October 2025

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Exploration of imaging and molecular biomarkers for differentiation of neuropathic corneal pain from dry eye syndrome.
Jun Cheng, Chang Liu, Mingyi Yu, Isabelle Xin Yu Lee, Xinyue Wang

Ocul Surf· October 2025

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Applicability Domain of Peroxidase Peptide Reactivity Assay (PPRA): Chemical Structure Analysis and Grouping of Peptide Depletion Patterns.
Gang Yan, Petra S Kern, Kim Ellingson, Mengying Zhang, G Frank Gerberick, Isabelle Lee

Chem Res Toxicol· October 2025

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Evaluation of and release of recombinant human nerve growth factor from bioengineered human stromal lenticule.
Molly Tzu-Yu Lin, Yu-Chi Liu, Isabelle Xin Yu Lee, Domitilla Mandatori, Nicola Detta

Front Bioeng Biotechnol· October 2025

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Vitamin abnormalities in neuropathic corneal pain.
Bing Jie Chow, Mingyi Yu, Chang Liu, Isabelle Xin Yu Lee, Louis Tong

Eye Vis (Lond)· October 2025

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Updates to the Research Institute for Fragrance Materials, Inc. Confirmation of No Induction in Human Test Standard Protocol.
Maura Lavelle, Isabelle Lee, Devin O'Brien, Mihwa Na, Anne Marie Api

Dermatitis· September 2025

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Smoking negatively impacts ocular surface health and corneal nerve metrics.
Ansa Anam, Mingyi Yu, Chang Liu, Isabelle Xin Yu Lee, Juanita Yang

Ocul Surf· July 2025

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EU roadmap for phasing out animal testing for chemical safety assessments: Recommendations from a multi-stakeholder roundtable.
Laurence Walder, Giorgia Pallocca, Luísa F Bastos, Manon Beekhuijzen, Francois Busquet, Isabelle Lee

ALTEX· July 2025

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Evaluation of Corneal Sensitivity: Tools We Have.
Ezra Eio, Mingyi Yu, Chang Liu, Isabelle Xin Yu Lee, Regina Kay Ting Wong

Diagnostics (Basel)· July 2025

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Neuropathic corneal pain following refractive surgery: risk factors, clinical manifestations, imaging and proteomic characteristics.
Calesta Hui Yi Teo, Chang Liu, Isabelle Xin Yu Lee, Molly Tzu-Yu Lin, Fengyi Liu

Br J Ophthalmol· June 2025

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Tear Cytokine Changes up to One Year After Allogeneic Hematopoietic Stem Cell Transplant: Effect of Daily Topical Cyclosporine-A 0.1% Emulsion.
Louis Tong, Yu-Chi Liu, Sharon Wan Jie Yeo, Chang Liu, Isabelle Xin Yu Lee

Int J Mol Sci· June 2025

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Determining a point of departure for skin sensitization potency and quantitative risk assessment of fragrance ingredients using the GARDskin dose-response assay.
Isabelle Lee, Andy Forreryd, Mihwa Na, Isabella Schember, Maura Lavelle

ALTEX· April 2025

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Randomized controlled trial on corneal denervation, neuroinflammation and ocular surface in corneal lenticule extraction for advanced refractive correction (CLEAR) and small incision lenticule extraction (SMILE).
Mingyi Yu, Chang Liu, Isabelle Xin Yu Lee, Victor Wei-Tse Hsu, Regina Kay Ting Wong

Eye Vis (Lond)· April 2025

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Efficacy and Safety of Donut-Shaped Circumferential Spine CyberKnife Stereotactic Body Radiotherapy for Metastatic Spine Disease.
David J Park, Isabelle Lee, Shreyas Annagiri, Kuan-Nien Chou, Aroosa Zamarud

Neurosurgery· April 2025

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Obesity negatively impacts corneal nerves in patients with diabetes mellitus.
Calesta Hui Yi Teo, Chang Liu, Mingyi Yu, Isabelle Xin Yu Lee, Ansa Anam

Eye Vis (Lond)· April 2025

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Validation of the Ocular Pain Assessment Survey Instrument With Rasch Analysis.
Debbie Marie Ng, Xiu Wang, Chang Liu, MingYi Yu, Isabelle Xin Yu Lee

Transl Vis Sci Technol· February 2025

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Updating Reaction Mechanistic Domains for Skin Sensitization: 1. Nucleophilic Skin Sensitizers.
David W Roberts, Anne Marie Api, Aynur Aptula, Isabelle Lee, Holger Moustakas

Chem Res Toxicol· November 2024

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Predicting points of departure and potency categories for fragrance ingredients by integrating OECD in vitro models.
Isabelle Lee, Mihwa Na, Maura Lavelle, Isabella Schember, Cindy Ryan

Food Chem Toxicol· November 2024

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Quality of Life and Symptomatology in Neuropathic Corneal Pain in Comparison With Dry Eye Syndrome.
Jia Ying Chin, Louis Tong, Chang Liu, Isabelle Xin Yu Lee, Jipson Hon Fai Wong

Cornea· August 2024

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Potential therapeutic effects of peroxisome proliferator-activated receptors on corneal diseases.
Bing Jie Chow, Isabelle Xin Yu Lee, Chang Liu, Yu-Chi Liu

Exp Biol Med (Maywood)· July 2024

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Topical and oral peroxisome proliferator-activated receptor-α agonist ameliorates diabetic corneal neuropathy.
Hassan Mansoor, Isabelle Xin Yu Lee, Molly Tzu-Yu Lin, Heng Pei Ang, Yao Cong Xue

Sci Rep· June 2024

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