Publications by authors named "Anthony Sadler"

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The immune response to RNA suppresses nucleic acid synthesis by limiting ribose 5-phosphate.
Pushpak Bhattacharjee, Die Wang, Dovile Anderson, Joshua N Buckler, Eveline de Geus, Anthony J Sadler

EMBO J· July 2024

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Author Correction: The immune response to RNA suppresses nucleic acid synthesis by limiting ribose 5-phosphate.
Pushpak Bhattacharjee, Die Wang, Dovile Anderson, Joshua N Buckler, Eveline de Geus, Anthony J Sadler

EMBO J· July 2024

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Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC.
Danfeng Dong, Yuzhang Du, Xuefeng Fei, Hao Yang, Xiaofang Li, Anthony Sadler

Nat Commun· December 2023

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The protein kinase R modifies gut physiology to limit colitis.
Howard Chi Ho Yim, Arindam Chakrabarti, Sean Kessler, Hiroyuki Morimoto, Die Wang, Anthony J Sadler

Front Immunol· March 2023

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Inhibition of UBA6 by inosine augments tumour immunogenicity and responses.
Lei Zhang, Li Jiang, Liang Yu, Qin Li, Xiangjun Tian, Anthony J Sadler

Nat Commun· September 2022

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A Viral NOD to Encephalitis.
Anthony J Sadler

J Virol· July 2022

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Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24.
Sophia Davidson, Chien-Hsiung Yu, Annemarie Steiner, Frédéric Ebstein, Paul J Baker, Anthony J Sadler

Sci Immunol· February 2022

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The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53.
Anette Szczepny, Kirstyn Carey, Lisa McKenzie, W Samantha N Jayasekara, Fernando Rossello, Anthony J Sadler

Oncogene· April 2018

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The role of MDA5 in the development of autoimmune disease.
Anthony J Sadler

J Leukoc Biol· February 2018

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The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation.
Yu Dou, Howard Ch Yim, Carl D Kirkwood, Bryan Rg Williams, Anthony J Sadler

EMBO J· September 2017

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Auto-phosphorylation Represses Protein Kinase R Activity.
Die Wang, Nicole A de Weerd, Belinda Willard, Galina Polekhina, Bryan R G Williams, Anthony J Sadler

Sci Rep· March 2017

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The kinase activity of PKR represses inflammasome activity.
Howard C H Yim, Die Wang, Liang Yu, Christine L White, Pieter W Faber, Anthony J Sadler

Cell Res· March 2016

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The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.
Benjamin K Dickerman, Christine L White, Patricia M Kessler, Anthony J Sadler, Bryan R G Williams

FEBS J· December 2015

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The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.
Anthony J Sadler, Bandar A Suliman, Liang Yu, Xiangliang Yuan, Die Wang

Nat Commun· April 2015

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BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs.
Anthony J Sadler, Fernando J Rossello, Liang Yu, James A Deane, Xiangliang Yuan

Proc Natl Acad Sci U S A· February 2015

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Molecular dynamics reveal a novel kinase-substrate interface that regulates protein translation.
Ming S Liu, Die Wang, Hiroyuki Morimoto, Howard C H Yim, Aaron T Irving, Anthony J Sadler

J Mol Cell Biol· December 2014

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Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling.
Badia Barakat, Liang Yu, Camden Lo, Duc Vu, Elisabetta De Luca, Anthony J Sadler

EMBO Rep· September 2013

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ATF3 suppresses metastasis of bladder cancer by regulating gelsolin-mediated remodeling of the actin cytoskeleton.
Xiangliang Yuan, Liang Yu, Junhua Li, Guohua Xie, Tingting Rong, Anthony J Sadler

Cancer Res· June 2013

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Mitochondrially localised MUL1 is a novel modulator of antiviral signaling.
Kristie Jenkins, Jing Jing Khoo, Anthony Sadler, Rebecca Piganis, Die Wang

Immunol Cell Biol· April 2013

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Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly.
Simone A Beckham, Jason Brouwer, Anna Roth, Die Wang, Anthony J Sadler

Nucleic Acids Res· March 2013

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Regulation of actin dynamics by protein kinase R control of gelsolin enforces basal innate immune defense.
Aaron T Irving, Die Wang, Oliver Vasilevski, Olivier Latchoumanin, Noga Kozer, Anthony J Sadler

Immunity· May 2012

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Dynamiting viruses with MxA.
Anthony J Sadler, Bryan R G Williams

Immunity· October 2011

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The role of protein kinase R in the interferon response.
Agnieszka Pindel, Anthony Sadler

J Interferon Cytokine Res· January 2011

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Influenza A infection enhances cross-priming of CD8+ T cells to cell-associated antigens in a TLR7- and type I IFN-dependent fashion.
Joe Wei, Jason Waithman, Roleen Lata, Nicole A Mifsud, Jonathan Cebon, Anthony J Sadler

J Immunol· November 2010

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Orchestration of the activation of protein kinase R by the RNA-binding motif.
Anthony J Sadler

J Interferon Cytokine Res· April 2010

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