Publications by authors named "Jason Brouwer"

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Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Michelle S Miller, Angus D Cowan, Jason M Brouwer, Sean T Smyth, Liuyu Peng

FEBS J· June 2024

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A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells.
Hema Preethi Subas Satish, Sweta Iyer, Melissa X Shi, Agnes W Wong, Karla C Fischer, Jason M Brouwer

Cell Death Differ· June 2024

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Structure of detergent-activated BAK dimers derived from the inert monomer.
Richard W Birkinshaw, Sweta Iyer, Daisy Lio, Cindy S Luo, Jason M Brouwer

Mol Cell· May 2021

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BAK core dimers bind lipids and can be bridged by them.
Angus D Cowan, Nicholas A Smith, Jarrod J Sandow, Eugene A Kapp, Yepy H Rustam, Jason M Brouwer

Nat Struct Mol Biol· November 2020

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A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis.
Mark F van Delft, Stephane Chappaz, Yelena Khakham, Chinh T Bui, Marlyse A Debrincat, Jason M Brouwer

Nat Chem Biol· November 2019

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Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy.
Jonathan P Bernardini, Jason M Brouwer, Iris Kl Tan, Jarrod J Sandow, Shuai Huang

EMBO J· January 2019

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Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Jason M Brouwer, Ping Lan, Angus D Cowan, Jonathan P Bernardini, Richard W Birkinshaw

Mol Cell· November 2017

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Disordered clusters of Bak dimers rupture mitochondria during apoptosis.
Rachel T Uren, Martin O'Hely, Sweta Iyer, Ray Bartolo, Melissa X Shi, Jason M Brouwer

Elife· February 2017

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Bak core and latch domains separate during activation, and freed core domains form symmetric homodimers.
Jason M Brouwer, Dana Westphal, Grant Dewson, Adeline Y Robin, Rachel T Uren

Mol Cell· September 2014

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Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly.
Simone A Beckham, Jason Brouwer, Anna Roth, Die Wang, Anthony J Sadler

Nucleic Acids Res· March 2013

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Engineering a structure switching mechanism into a steroid-binding aptamer and hydrodynamic analysis of the ligand binding mechanism.
Oren Reinstein, Miguel A D Neves, Makbul Saad, Sherry N Boodram, Stephanie Lombardo, Jason Brouwer

Biochemistry· November 2011

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Parents of preschoolers: expert media recommendations and ratings knowledge, media-effects beliefs, and monitoring practices.
Jeanne B Funk, Jason Brouwer, Kathleen Curtiss, Evan McBroom

Pediatrics· March 2009

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