Publications by authors named "Anthony Turpoff"

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Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy.
Hasane Ratni, Gary M Karp, Marla Weetall, Nikolai A Naryshkin, Sergey V Paushkin, Anthony Turpoff

J Med Chem· July 2016

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Discovery and Optimization of Small Molecule Splicing Modifiers of Survival Motor Neuron 2 as a Treatment for Spinal Muscular Atrophy.
Matthew G Woll, Hongyan Qi, Anthony Turpoff, Nanjing Zhang, Xiaoyan Zhang

J Med Chem· July 2016

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Discovery of 2-(4-sulfonamidophenyl)-indole 3-carboxamides as potent and selective inhibitors with broad hepatitis C virus genotype activity targeting HCV NS4B.
Nanjing Zhang, Anthony Turpoff, Xiaoyan Zhang, Song Huang, Yalei Liu

Bioorg Med Chem Lett· January 2016

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6-(Azaindol-2-yl)pyridine-3-sulfonamides as potent and selective inhibitors targeting hepatitis C virus NS4B.
Guangming Chen, Hongyu Ren, Nanjing Zhang, William Lennox, Anthony Turpoff

Bioorg Med Chem Lett· February 2015

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Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.
Nikolai A Naryshkin, Marla Weetall, Amal Dakka, Jana Narasimhan, Xin Zhao, Anthony Turpoff

Science· August 2014

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Structure-activity relationship (SAR) optimization of 6-(indol-2-yl)pyridine-3-sulfonamides: identification of potent, selective, and orally bioavailable small molecules targeting hepatitis C (HCV) NS4B.
Nanjing Zhang, Xiaoyan Zhang, Jin Zhu, Anthony Turpoff, Guangming Chen

J Med Chem· March 2014

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Discovery of N-(4'-(indol-2-yl)phenyl)sulfonamides as novel inhibitors of HCV replication.
Guangming Chen, Hongyu Ren, Anthony Turpoff, Alexander Arefolov, Richard Wilde

Bioorg Med Chem Lett· July 2013

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Discovery of novel HCV inhibitors: synthesis and biological activity of 6-(indol-2-yl)pyridine-3-sulfonamides targeting hepatitis C virus NS4B.
Xiaoyan Zhang, Nanjing Zhang, Guangming Chen, Anthony Turpoff, Hongyu Ren

Bioorg Med Chem Lett· July 2013

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PTC124 targets genetic disorders caused by nonsense mutations.
Ellen M Welch, Elisabeth R Barton, Jin Zhuo, Yuki Tomizawa, Westley J Friesen, Anthony A Turpoff

Nature· May 2007

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