Publications by authors named "Matthew G Woll"

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Splicing Modulators as a Therapeutic Strategy for Tauopathies.
M Catarina Silva, Hannah Lindmeier, Paolo Pigini, Jennifer Laughlin, Yong Yu, Matthew G Woll

bioRxiv· May 2025

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Development of an oral treatment that rescues gait ataxia and retinal degeneration in a phenotypic mouse model of familial dysautonomia.
Elisabetta Morini, Anil Chekuri, Emily M Logan, Jessica M Bolduc, Emily G Kirchner, Matthew G Woll

Am J Hum Genet· March 2023

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Targeting strategies for modulating pre-mRNA splicing with small molecules: Recent advances.
Scott J Barraza, Anuradha Bhattacharyya, Christopher R Trotta, Matthew G Woll

Drug Discov Today· January 2023

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Small molecule splicing modifiers with systemic HTT-lowering activity.
Anuradha Bhattacharyya, Christopher R Trotta, Jana Narasimhan, Kari J Wiedinger, Wencheng Li, Matthew G Woll

Nat Commun· December 2021

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A deep learning approach to identify gene targets of a therapeutic for human splicing disorders.
Dadi Gao, Elisabetta Morini, Monica Salani, Aram J Krauson, Anil Chekuri, Matthew G Woll

Nat Commun· June 2021

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Correction to Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-Negative Bacteria.
Aleksey I Gerasyuto, Michael A Arnold, Jiashi Wang, Guangming Chen, Xiaoyan Zhang, Matthew G Woll

J Med Chem· October 2018

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Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-Pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-negative Bacteria.
Aleksey I Gerasyuto, Michael A Arnold, Jiashi Wang, Guangming Chen, Xiaoyan Zhang, Matthew G Woll

J Med Chem· May 2018

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Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy.
Hasane Ratni, Gary M Karp, Marla Weetall, Nikolai A Naryshkin, Sergey V Paushkin, Matthew G Woll

J Med Chem· July 2016

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Discovery and Optimization of Small Molecule Splicing Modifiers of Survival Motor Neuron 2 as a Treatment for Spinal Muscular Atrophy.
Matthew G Woll, Hongyan Qi, Anthony Turpoff, Nanjing Zhang, Xiaoyan Zhang

J Med Chem· July 2016

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Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.
Nikolai A Naryshkin, Marla Weetall, Amal Dakka, Jana Narasimhan, Xin Zhao, Matthew G Woll

Science· August 2014

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Asymmetric cooperative catalysis of strong Brønsted acid-promoted reactions using chiral ureas.
Hao Xu, Stephan J Zuend, Matthew G Woll, Ye Tao, Eric N Jacobsen

Science· February 2010

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Solution structure of a small protein containing a fluorinated side chain in the core.
Gabriel Cornilescu, Erik B Hadley, Matthew G Woll, John L Markley, Samuel H Gellman

Protein Sci· September 2007

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Solution structure of a small protein containing a fluorinated side chain in the core.
Gabriel Cornilescu, Erik B Hadley, Matthew G Woll, John L Markley, Samuel H Gellman

Protein Sci· January 2007

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Stabilizing and destabilizing effects of phenylalanine --> F5-phenylalanine mutations on the folding of a small protein.
Matthew G Woll, Erik B Hadley, Sandro Mecozzi, Samuel H Gellman

J Am Chem Soc· December 2006

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Backbone thioester exchange: a new approach to evaluating higher order structural stability in polypeptides.
Matthew G Woll, Samuel H Gellman

J Am Chem Soc· September 2004

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Stereoselective synthesis of 3-substituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into short 12-helical beta-peptides that fold in water.
Matthew G Woll, John D Fisk, Paul R LePlae, Samuel H Gellman

J Am Chem Soc· October 2002

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