Publications by authors named "Anu R Sawkar"

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Pharmacologic chaperoning as a strategy to treat Gaucher disease.
Zhanqian Yu, Anu R Sawkar, Jeffery W Kelly

FEBS J· October 2007

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Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention.
Zhanqian Yu, Anu R Sawkar, Lisa J Whalen, Chi-Huey Wong, Jeffery W Kelly

J Med Chem· January 2007

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Chemical chaperones and permissive temperatures alter localization of Gaucher disease associated glucocerebrosidase variants.
Anu R Sawkar, Martina Schmitz, Klaus-Peter Zimmer, David Reczek, Tim Edmunds

ACS Chem Biol· May 2006

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Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles.
Anu R Sawkar, Sara L Adamski-Werner, Wei-Chieh Cheng, Chi-Huey Wong, Ernest Beutler

Chem Biol· November 2005

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X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease.
Lakshmanane Premkumar, Anu R Sawkar, Swetlana Boldin-Adamsky, Lilly Toker, Israel Silman

J Biol Chem· June 2005

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The biological and chemical basis for tissue-selective amyloid disease.
Yoshiki Sekijima, R Luke Wiseman, Jeanne Matteson, Per Hammarström, Sean R Miller, Anu R Sawkar

Cell· April 2005

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Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease.
Anu R Sawkar, Wei-Chieh Cheng, Ernest Beutler, Chi-Huey Wong, William E Balch

Proc Natl Acad Sci U S A· November 2002

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