Publications by authors named "April S Chan"

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Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression.
Sarah S K Yue, Yin Tong, Hoi Cheong Siu, Siu Lun Ho, Simon Y K Law, Dessy Chan, Annie S Y Chan, April S Chan

Gut· March 2025

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Organoid cultures for cancer modeling.
Helen H N Yan, April S Chan, Frank Pui-Ling Lai, Suet Yi Leung

Cell Stem Cell· July 2023

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Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models.
Yin Tong, Priscilla S W Cheng, Chung Sze Or, Sarah S K Yue, Hoi Cheong Siu, Dessy Chan, Annie S Y Chan, April S Chan

Gut· February 2023

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A Bayesian model for identifying cancer subtypes from paired methylation profiles.
Yetian Fan, April S Chan, Jun Zhu, Suet Yi Leung, Xiaodan Fan

Brief Bioinform· January 2023

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Oncogenic mutations drive intestinal cancer initiation through paracrine remodeling.
Helen H N Yan, April S Chan, Suet Yi Leung

Cancer Cell· July 2021

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Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles.
Helen H N Yan, Hoi Cheong Siu, Siu Lun Ho, Sarah S K Yue, Yang Gao, Dessy Chan, April S Chan, Annie S Y Chan, Anthony K W Chan

Gut· December 2020

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Breakthrough Moments: Organoid Models of Cancer.
April S Chan, Helen H N Yan, Suet Yi Leung

Cell Stem Cell· June 2019

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A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.
Helen H N Yan, Hoi Cheong Siu, Simon Law, Siu Lun Ho, Sarah S K Yue, Dessy Chan, April S Chan, Annie S Y Chan, Anthony K W Chan

Cell Stem Cell· December 2018

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MICMIC: identification of DNA methylation of distal regulatory regions with causal effects on tumorigenesis.
Yin Tong, Jianlong Sun, Chi Fat Wong, Qingzheng Kang, Beibei Ru, April Sheila Chan

Genome Biol· June 2018

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Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation.
Marianna Papaspyridonos, Irina Matei, Yujie Huang, Maria do Rosario Andre, Helene Brazier-Mitouart, April S Chan

Nat Commun· April 2015

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Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.
Kai Wang, Siu Tsan Yuen, Jiangchun Xu, Siu Po Lee, Helen H N Yan, Kok Hoe Chan, Annie S Y Chan, Anthony K W Chan, April S Chan

Nat Genet· June 2014

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Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.
April S Chan, Kristian K Jensen, Dimitris Skokos, Stephen Doty, Hannah K Lederman

PLoS One· November 2009

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Inheritance of most X-linked traits is not dominant or recessive, just X-linked.
William B Dobyns, Allison Filauro, Brett N Tomson, April S Chan, Allen W Ho

Am J Med Genet A· August 2004

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