Publications by authors named "Arafa Musa"

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Ferulic Acid Ameliorates Chromium-Induced Nephrotoxicity: Modulation of PERK/eIF2α/ATF4/CHOP, Nrf2, and Inflammatory Signaling.
Samyah T Alanazi, Samir A Salama, Musaad M Althobaiti, Abdullah M Almalki, Afnan Bakhsh, Arafa Musa

Biol Trace Elem Res· November 2025

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From chemistry to targeted cancer therapy: potent benzimidazole-1,2,3-triazole hybrid-loaded nanogels against breast and colorectal malignancies.
Azizah M Malebari, Mohamed A M Ali, Arafa Musa, Magdi E A Zaki, Sobhi M Gomha

RSC Adv· November 2025

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Flufenamic acid-based sulfonohydrazide and acetamide derivatives NSAI as inhibitors of multi-targets COX-1/COX-2/5-LOX: design, synthesis, in silico ADMET and binding mode studies.
Shaimaa Hussein, Eman A Fayed, Ahmed Ragab, Moustafa S Abusaif, Yousry A Ammar, Arafa Musa

BMC Chem· October 2025

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Assembling of phenyl substituted halogens in the C3-position of substituted isatins by mono wave assisted synthesis: development of a new class of monoamine oxidase inhibitors.
Della Grace Thomas Parambi, Stephanus J Cloete, Sunil Kumar, Tariq Ghazi Alsahli, Arafa Musa

J Comput Aided Mol Des· September 2025

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Design, synthesis, and cytotoxic evaluation of quinazoline-based derivatives as VEGER-2 inhibitors: comparative study against EGFR kinase activity, induction of apoptosis, and molecular docking study.
Reda R Mabrouk, Arafa Musa, Maged Mohammed Saleh Al Ward, Shaimaa Hussein, Ahmed K B Aljohani

RSC Adv· August 2025

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GC-MS and HPLC-FLD for sensitive assay of toxic cyclohexylamine in artificial sweetener tablets and human biological fluids.
Hazim M Ali, Amr A Essawy, Ahmed Hamad Alanazi, Arafa Musa, Ahmed Emad F Abbas

Food Chem Toxicol· July 2025

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Alleviation of Copper-Induced Hepatotoxicity by Bergenin: Diminution of Oxidative Stress, Inflammation, and Apoptosis via Targeting SIRT1/FOXO3a/NF-κB Axes and p38 MAPK Signaling.
Samyah T Alanazi, Samir A Salama, Musaad M Althobaiti, Rana A Alotaibi, Ammar A AlAbdullatif, Arafa Musa

Biol Trace Elem Res· June 2025

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Design, synthesis, and biological investigation of new thiazole-based derivatives as multi-targeted inhibitors endowed with antiproliferative, antioxidant, and antibacterial properties.
Hesham A M Gomaa, Asmaa M Atta, Mohamed E Shaker, Sami I Alzarea, Tariq G Alsahli, Arafa Musa

Front Chem· May 2025

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Phenyltriazole-based sulfonamides: novel dual-target agents against MRSA biofilms and resistant pathogens.
Abdelrahman Hussien, Arafa Musa, Hanzada T Nour El-Din, Ahmed M Helal, Yosra I Nagy

RSC Adv· May 2025

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Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade.
Samyah T Alanazi, Samir A Salama, Musaad M Althobaiti, Afnan Bakhsh, Najla M Aljehani, Arafa Musa

Food Chem Toxicol· April 2025

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Design and construction of novel pyridine-pyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox studies.
Mohamed E Shaker, Hesham A M Goma, Izzeddin Alsalahat, Nadia A A Elkanzi, Amany A Azouz, Arafa Musa

J Biomol Struct Dyn· March 2025

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Rational design and synthesis of novel phenyltriazole derivatives targeting MRSA cell wall biosynthesis.
Mohamed M Elsebaei, Hany G Ezzat, Ahmed M Helal, Mohamed H El-Shershaby, Mohammed S Abdulrahman, Arafa Musa

RSC Adv· December 2024

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Introducing of novel class of pyrano[2,3-]pyrazole-5-carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic and CNS toxicity profiles supported by molecular dynamic simulation.
Mohammed Almaghrabi, Arafa Musa, Ahmed K B Aljohani, Hany E A Ahmed, Marwa Alsulaimany

J Biomol Struct Dyn· November 2024

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The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, , and mechanistic investigations.
Arafa Musa, Saleh K Ihmaid, David L Hughes, Musa A Said, Hamada S Abulkhair

J Biomol Struct Dyn· December 2023

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Cytotoxic and Antioxidant Potential of Forssk Essential Oil Growing in Northern Saudi Arabia.
Ehab M Mostafa, Ahmed H El-Ghorab, Mohammed M Ghoneim, Hasnaa Ali Ebrahim, Moaz Abulfaraj, Arafa Musa

Molecules· October 2023

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Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study.
Della Grace Thomas Parambi, Jong Min Oh, Sunil Kumar, Sachithra Thazhathuveedu Sudevan, Omnia Magdy Hendawy, Arafa Musa

Comput Biol Chem· August 2023

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Phthalazone tethered 1,2,3-triazole conjugates: In silico molecular docking studies, synthesis, in vitro antiproliferative, and kinase inhibitory activities.
Mohamed A Abdelgawad, Syed Nasir Abbas Bukhari, Arafa Musa, Mohammed Elmowafy, AbdElAziz A Nayl

Bioorg Chem· April 2023

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Phenanthroindolizidine Alkaloids Secondary Metabolites Diversity in Medicinally Viable Plants of the Genus .
Ehab M Mostafa, Arafa Musa, Hamdoon A Mohammed, Abdulaziz Ibrahim Alzarea, Mohamed A Abdelgawad

Plants (Basel)· March 2023

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Phenylpyrazolone-1,2,3-triazole Hybrids as Potent Antiviral Agents with Promising SARS-CoV-2 Main Protease Inhibition Potential.
Arafa Musa, Hamada S Abulkhair, Ateyatallah Aljuhani, Nadjet Rezki, Mohamed A Abdelgawad

Pharmaceuticals (Basel)· March 2023

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Phytotoxic effects of dry leachates on germination, seedling growth, photosynthetic performance, and gene expression of economically important crops.
Haifa Abdulaziz Sakit ALHaithloul, Muhammad Ishfaq Khan, Arafa Musa, Mohammed M Ghoneim, Ayshah Aysh ALrashidi

PeerJ· January 2023

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Wound Healing and Antioxidant Properties of Supported by Metabolomic Profiling and Molecular Docking.
Shaimaa R Ahmed, Ehab M Mostafa, Arafa Musa, Enas Ezzat Rateb, Mohammad M Al-Sanea

Antioxidants (Basel)· November 2022

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Design, Synthesis, Molecular Modeling, and Anticancer Evaluation of New VEGFR-2 Inhibitors Based on the Indolin-2-One Scaffold.
Mohamed A Abdelgawad, Alaa M Hayallah, Syed Nasir Abbas Bukhari, Arafa Musa, Mohammed Elmowafy

Pharmaceuticals (Basel)· November 2022

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Screening and Molecular Docking of Bioactive Metabolites of the Red Sea Sponge as Potential Antimicrobial Agents.
Arafa Musa, Mohamed A Abdelgawad, Mohamed E Shaker, Ahmed H El-Ghorab, Della Grace Thomas Parambi

Antibiotics (Basel)· November 2022

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New Sulfamethoxazole Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, Cytotoxic Activity and Molecular Modeling.
Mohamed A Abdelgawad, Syed N A Bukhari, Arafa Musa, Mohammed Elmowafy, Mohammed H Elkomy

Pharmaceuticals (Basel)· September 2022

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LC/MS Profiling and Gold Nanoparticle Formulation of Major Metabolites from as Antibacterial and Antioxidant Potentialities.
Ahmed H El-Ghorab, Fathy A Behery, Mohamed A Abdelgawad, Ibrahim Hotan Alsohaimi, Arafa Musa

Plants (Basel)· July 2022

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