Publications by authors named "Arba Ager"

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Characterization of the Preclinical Pharmacology of the New 2-Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention.
Geoffrey W Birrell, Gavin D Heffernan, Guy A Schiehser, John Anderson, Arba L Ager

Antimicrob Agents Chemother· April 2018

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The eIF2α Kinase Heme-Regulated Inhibitor Protects the Host from Infection by Regulating Intracellular Pathogen Trafficking.
Wael Bahnan, Justin C Boucher, Petoria Gayle, Niraj Shrestha, Mark Rosen, Arba Ager

Infect Immun· March 2018

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Lead Selection of a New Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention.
Marina Chavchich, Geoffrey W Birrell, Arba L Ager, Donna O MacKenzie, Gavin D Heffernan

Antimicrob Agents Chemother· May 2016

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JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium.
Geoffrey W Birrell, Marina Chavchich, Arba L Ager, Hong-Ming Shieh, Gavin D Heffernan

Antimicrob Agents Chemother· January 2015

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A targeted and adjuvanted nanocarrier lowers the effective dose of liposomal amphotericin B and enhances adaptive immunity in murine cutaneous leishmaniasis.
Pirouz M Daftarian, Geoffrey W Stone, Leticia Kovalski, Manoj Kumar, Aram Vosoughi, Arba L Ager

J Infect Dis· December 2013

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Novel diaryl ureas with efficacy in a mouse model of malaria.
John W Anderson, Dimitri Sarantakis, Jacek Terpinski, T R Santha Kumar, Han-Chun Tsai, Arba L Ager

Bioorg Med Chem Lett· February 2013

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Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin.
Mihaela Perić, Andrea Fajdetić, Renata Rupčić, Sulejman Alihodžić, Dinko Ziher, Arba Ager

J Med Chem· February 2012

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Synthesis, structure-activity relationship, and antimalarial activity of ureas and thioureas of 15-membered azalides.
Mirjana Bukvić Krajačić, Mihaela Perić, Kirsten S Smith, Zrinka Ivezić Schönfeld, Dinko Žiher, Arba Ager

J Med Chem· May 2011

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The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.
Min Yu, T R Santha Kumar, Louis J Nkrumah, Alida Coppi, Silke Retzlaff, Arba Ager

Cell Host Microbe· December 2008

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Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate.
N P Dhammika Nanayakkara, Arba L Ager, Marilyn S Bartlett, Vanessa Yardley, Simon L Croft

Antimicrob Agents Chemother· June 2008

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Malaria causal prophylactic activity of imidazolidinedione derivatives.
Jian Guan, Xihong Wang, Kirsten Smith, Arba Ager, Montip Gettayacamin

J Med Chem· November 2007

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Antimalarial pharmacodynamics and pharmacokinetics of a third-generation antifolate--JPC2056--in cynomolgus monkeys using an in vivo in vitro model.
Michael D Edstein, Barbara M Kotecka, Arba L Ager, Kirsten S Smith, Charles A DiTusa

J Antimicrob Chemother· October 2007

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Antimalarial activities of new pyrrolo[3,2-f]quinazoline-1,3-diamine derivatives.
Jian Guan, Quan Zhang, Michael O'Neil, Nicanor Obaldia, Arba Ager

Antimicrob Agents Chemother· December 2005

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Unambiguous synthesis and prophylactic antimalarial activities of imidazolidinedione derivatives.
Quan Zhang, Jian Guan, John Sacci, Arba Ager, William Ellis

J Med Chem· October 2005

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Structure-activity relationships of the antimalarial agent artemisinin. 7. Direct modification of (+)-artemisinin and in vivo antimalarial screening of new, potential preclinical antimalarial candidates.
Mitchell A Avery, Maria Alvim-Gaston, Jeffrey A Vroman, Baogen Wu, Arba Ager

J Med Chem· September 2002

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