Publications by authors named "Aref Zayed"

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Cytotoxic, anti-inflammatory, antioxidant, and anti-glyoxalase-I evaluation of chelating substances: In silico and in vitro study.
MohammedBashar Al-Qazzan, Qosay Al-Balas, Belal Alnajjar, Violet Kasabri, Yusuf Al-Hiari, Aref Zayed

PLoS One· October 2025

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Resveratrol alters erlotinib pharmacokinetics in rats: application of a rapid HPLC-fluorescence method for quantifying erlotinib in plasma.
Aref L Zayed, Jomana Al Hroot, Ruba S Darweesh, Nidal A Qinna, Aysheh M Alshekhhossin

Naunyn Schmiedebergs Arch Pharmacol· July 2025

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Rapid and sensitive HPLC with fluorescence detection method for quantifying selpercatinib in liver microsomes and rat plasma: Implications for drug-drug interaction studies.
Aref L Zayed, Aysheh M Alshekhhossin, Omar M Al Kilani, Sana'a A Jaber, Leen L Dawood

J Chromatogr B Analyt Technol Biomed Life Sci· April 2025

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Development of a rapid HPLC-fluorescence method for monitoring warfarin metabolites formation: In vitro studies for evaluating the effect of piperine on warfarin metabolism and plasma coagulation.
Aref L Zayed, Mohammad Hadieh, Jomana Al Hroot, Fatima Hameedat, Sana'a A Jaber

Heliyon· May 2024

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Rapid high performance liquid chromatography method for erlotinib quantification in vitro: Application to study the effect of resveratrol on metabolism and cellular uptake of erlotinib.
Aref Zayed, Jomana Al Hroot, Abdulraouf Mayyas, Belal Al-Husein

Fundam Clin Pharmacol· October 2023

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HPLC methods for studying pharmacokinetics of tivozanib and in vitro metabolic interaction with dexamethasone in rat.
Aref L Zayed, Ghuroob N Hamadneh, Jomana Al Hroot, Abdulraouf Mayyas, Sana'a A Jaber

J Pharm Biomed Anal· August 2023

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HPLC with Fluorescence and Photodiode Array Detection for Quantifying Capmatinib in Biological Samples: Application to In Vivo and In Vitro Studies.
Aref Zayed, Sana'a A Jaber, Jomana Al Hroot, Sahar Hawamdeh, Nehad M Ayoub

Molecules· December 2022

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Postmortem sampling time effect on toxicity biomarkers in rats exposed to an acute lethal methomyl dose.
Shreen D Nusair, Mohammad Ananbeh, Aref Zayed, Mohammad I Ahmad, Nidal A Qinna

Toxicol Rep· August 2022

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High Performance Liquid Chromatography (HPLC) with Fluorescence Detection for Quantification of Steroids in Clinical, Pharmaceutical, and Environmental Samples: A Review.
Fatima Hameedat, Sahar Hawamdeh, Soraya Alnabulsi, Aref Zayed

Molecules· March 2022

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Calcium-Sensing Receptor Antagonist NPS-2143 Inhibits Breast Cancer cell Proliferation, Migration and Invasion via Downregulation of p-ERK1/2, Bcl-2 and Integrin β1 and Induces Caspase 3/7 Activation.
Mohammad A Y Alqudah, Marwah Azaizeh, Aref Zayed, Leen Asaad

Adv Pharm Bull· March 2022

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The effect of grape seed and green tea extracts on the pharmacokinetics of imatinib and its main metabolite, N-desmethyl imatinib, in rats.
Ruba S Darweesh, Tamam El-Elimat, Aref Zayed, Tareq N Khamis, Wahby M Babaresh

BMC Pharmacol Toxicol· November 2020

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Simultaneous determination of warfarin and 7-hydroxywarfarin in rat plasma by HPLC-FLD.
Aref Zayed, Wahby M Babaresh, Ruba S Darweesh, Tamam El-Elimat

Acta Pharm· September 2020

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The effect of hawthorn flower and leaf extract ( Spp.) on cardiac hemostasis and oxidative parameters in Sprague Dawley rats.
Abeer M Rababa'h, Omar N Al Yacoub, Tamam El-Elimat, Mo'ath Rabab'ah, Salah Altarabsheh, Aref Zayed

Heliyon· August 2020

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Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking.
Suaad A Audat, Nizar A Al-Shar'i, Buthina A Al-Oudat, Amanda Bryant-Friedrich, Mel F Bedi, Aref L Zayed

Molecules· June 2020

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Piperine Alters the Pharmacokinetics and Anticoagulation of Warfarin in Rats.
Aref Zayed, Wahby M Babaresh, Ruba S Darweesh, Tamam El-Elimat, Sahar S Hawamdeh

J Exp Pharmacol· June 2020

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Development and Validation of a Rapid High-Performance Liquid Chromatography⁻Tandem Mass Spectrometric Method for Determination of Folic Acid in Human Plasma.
Aref Zayed, Rana Bustami, Wafaa Alabsi, Tamam El-Elimat

Pharmaceuticals (Basel)· May 2018

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Low Molecular Weight Chitosan-Coated PLGA Nanoparticles for Pulmonary Delivery of Tobramycin for Cystic Fibrosis.
Nusaiba K Al-Nemrawi, Nid''A H Alshraiedeh, Aref L Zayed, Bashar M Altaani

Pharmaceuticals (Basel)· March 2018

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Speciation of oxaliplatin adducts with DNA nucleotides.
Aref Zayed, George D D Jones, Helen J Reid, Tamer Shoeib, Sarah E Taylor

Metallomics· October 2011

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Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interaction.
Kuresh A Youdim, Aref Zayed, Maurice Dickins, Alex Phipps, Michelle Griffiths

Br J Clin Pharmacol· May 2008

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