Publications by authors named "George D D Jones"

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FLASH-induced DNA damage reduction measured in vitro correlates with effective oxygen depletion determined in silico: further support for oxygen depletion contributing to FLASH's reduced damage burden in vitro.
Bethany Rothwell, Christian R Cooper, Donald J L Jones, Michael J Merchant, Norman F Kirkby, George D D Jones

Br J Radiol· July 2025

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Comet Assay Profiling of FLASH-Induced Damage: Mechanistic Insights into the Effects of FLASH Irradiation.
Christian R Cooper, Donald J L Jones, George D D Jones, Kristoffer Petersson

Int J Mol Sci· April 2023

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Calibration of the comet assay using ionising radiation.
Gunnar Brunborg, Dag M Eide, Anne Graupner, Kristine Gutzkow, Sergey Shaposhnikov, George D D Jones

Mutat Res Genet Toxicol Environ Mutagen· January 2023

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ATM Regulates Differentiation of Myofibroblastic Cancer-Associated Fibroblasts and Can Be Targeted to Overcome Immunotherapy Resistance.
Massimiliano Mellone, Klaudia Piotrowska, Giulia Venturi, Lija James, Aleksandra Bzura, George D D Jones

Cancer Res· December 2022

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Influence of skin melanisation and ultraviolet radiation on biomarkers of systemic oxidative stress.
Barbara B Shih, Mark D Farrar, Andy Vail, Donald Allan, Mu-Rong Chao, George D D Jones

Free Radic Biol Med· November 2020

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Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thymine Dimers across Both the Nuclear and Mitochondrial Genomes.
Alaa S Alhegaili, Yunhee Ji, Nicolas Sylvius, Matthew J Blades, Mahsa Karbaschi, George D D Jones

Int J Mol Sci· October 2019

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CD40L/IL-4-stimulated CLL demonstrates variation in translational regulation of DNA damage response genes including ATM.
Larissa Lezina, Ruth V Spriggs, Daniel Beck, Carolyn Jones, Kate M Dudek, George D D Jones

Blood Adv· August 2018

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MTH1 deficiency selectively increases non-cytotoxic oxidative DNA damage in lung cancer cells: more bad news than good?
Hussein H K Abbas, Kheloud M H Alhamoudi, Mark D Evans, George D D Jones, Steven S Foster

BMC Cancer· April 2018

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Posttranscriptional Upregulation of p53 by Reactive Oxygen Species in Chronic Lymphocytic Leukemia.
Jesvin Samuel, Sandrine Jayne, Yixiang Chen, Aneela Majid, Alice Wignall, George D D Jones

Cancer Res· November 2016

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BTK Modulates p53 Activity to Enhance Apoptotic and Senescent Responses.
Mohammad Althubiti, Miran Rada, Jesvin Samuel, Josep M Escorsa, Hishyar Najeeb, George D D Jones

Cancer Res· September 2016

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Loss of Nek11 Prevents G2/M Arrest and Promotes Cell Death in HCT116 Colorectal Cancer Cells Exposed to Therapeutic DNA Damaging Agents.
Sarah R Sabir, Navdeep K Sahota, George D D Jones, Andrew M Fry

PLoS One· June 2016

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Comet assay measures of DNA damage as biomarkers of irinotecan response in colorectal cancer in vitro and in vivo.
Joanna P Wood, Andrew J O Smith, Karen J Bowman, Anne L Thomas, George D D Jones

Cancer Med· September 2015

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A feasibility study of the use of saliva as an alternative to leukocytes as a source of DNA for the study of Pt-DNA adducts in cancer patients receiving platinum-based chemotherapy.
Sarah E Taylor, Joanna P Wood, Anne L Thomas, George D D Jones, Helen J Reid

Anal Bioanal Chem· December 2014

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Variation of DNA damage levels in peripheral blood mononuclear cells isolated in different laboratories.
Roger W L Godschalk, Clara Ersson, Maciej Stępnik, Magdalena Ferlińska, Jadwiga Palus, George D D Jones

Mutagenesis· July 2014

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Anthocyans as tertiary chemopreventive agents in bladder cancer: anti-oxidant mechanisms and interaction with mitomycin C.
Jennifer A Higgins, Murizal Zainol, Karen Brown, George D D Jones

Mutagenesis· July 2014

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Radiogenomics: radiobiology enters the era of big data and team science.
Barry S Rosenstein, Catharine M West, Søren M Bentzen, Jan Alsner, Christian Nicolaj Andreassen, George D D Jones

Int J Radiat Oncol Biol Phys· July 2014

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Comet assay measures of DNA damage are predictive of bladder cancer cell treatment sensitivity in vitro and outcome in vivo.
Karen J Bowman, Manar M Al-Moneef, Benedict T Sherwood, Alexandra J Colquhoun, Jonathan C Goddard, George D D Jones

Int J Cancer· March 2014

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Assessment of reproducibility in depletion and enrichment workflows for plasma proteomics using label-free quantitative data-independent LC-MS.
Amirmansoor Hakimi, Janica Auluck, George D D Jones, Leong L Ng, Donald J L Jones

Proteomics· January 2014

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DNA-repair measurements by use of the modified comet assay: an inter-laboratory comparison within the European Comet Assay Validation Group (ECVAG).
Roger W L Godschalk, Clara Ersson, Patrizia Riso, Marisa Porrini, Sabine A S Langie, George D D Jones

Mutat Res· September 2013

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DNA damage of macrophages induced by metal nanoparticulates using an air-liquid interface exposure model.
Jonathan Grigg, Ananth Tellabati, George D D Jones, Paul Howes

Nanotoxicology· August 2013

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An ECVAG inter-laboratory validation study of the comet assay: inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells.
Clara Ersson, Peter Møller, Lykke Forchhammer, Steffen Loft, Amaya Azqueta, George D D Jones

Mutagenesis· May 2013

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Inter-laboratory variation in DNA damage using a standard comet assay protocol.
Lykke Forchhammer, Clara Ersson, Steffen Loft, Lennart Möller, Roger W L Godschalk, George D D Jones

Mutagenesis· November 2012

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Reactive oxygen species and mitochondrial sensitivity to oxidative stress determine induction of cancer cell death by p21.
Ionica Masgras, Samantha Carrera, Petra J de Verdier, Paul Brennan, Aneela Majid, George D D Jones

J Biol Chem· March 2012

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Speciation of oxaliplatin adducts with DNA nucleotides.
Aref Zayed, George D D Jones, Helen J Reid, Tamer Shoeib, Sarah E Taylor

Metallomics· October 2011

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Simplified method for the collection, storage, and comet assay analysis of DNA damage in whole blood.
Kamla Al-Salmani, Hussein H K Abbas, Sjors Schulpen, Mahsa Karbaschi, Intisar Abdalla, George D D Jones

Free Radic Biol Med· August 2011

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