Publications by authors named "Arnav Mehta"

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Transcriptomic Plasticity is a Hallmark of Metastatic Pancreatic Cancer.
Alejandro Jiménez-Sánchez, Sitara Persad, Akimasa Hayashi, Shigeaki Umeda, Roshan Sharma, Arnav Mehta

Cancer Res· December 2025

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Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics.
Inbal Avraham-Davidi, Simon Mages, Johanna Klughammer, Noa Moriel, Shinya Imada, Arnav Mehta

Elife· December 2025

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Distinct spatially resolved tumor microenvironment trajectories define benefit from ramucirumab plus pembrolizumab in refractory PD-L1+ gastric cancer.
Sung Hee Lim, Minae An, You Jeong Heo, Hyuk Lee, Byung-Hoon Min, Arnav Mehta

Cancer Immunol Res· November 2025

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Melanoma to rhabdomyosarcoma plasticity in the setting of immunotherapy.
Andrew D Knight, Emily J Robitschek, Jia-Ren Lin, Dennie T Frederick, Alvin Shi, Arnav Mehta

medRxiv· November 2025

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Differential T cell clonal dynamics underlie outcomes to frontline chemoimmunotherapy in advanced gastric cancer.
Samuel J Wright, Sarah Kang, Minae An, You Jeong Heo, Milan Parikh, Arnav Mehta

medRxiv· August 2025

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Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants.
Or-Yam Revach, Angelina M Cicerchia, Ofir Shorer, Claire A Palin, Boryana Petrova, Arnav Mehta

Cell Rep Med· July 2025

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The Society for Immunotherapy of Cancer Perspective on Liquid Biopsy- and Radiomics-Based Technologies for Immuno-oncology Biomarker Discovery and Application.
Anne Monette, Adriana Aguilar-Mahecha, Emre Altinmakas, Mathew G Angelos, Nima Assad, Arnav Mehta

Clin Cancer Res· June 2025

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Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics.
Inbal Avraham-Davidi, Simon Mages, Johanna Klughammer, Noa Moriel, Shinya Imada, Arnav Mehta

bioRxiv· June 2025

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Comparative Evaluation of Therapeutic Efficacy and Safety of 90% Lactic Acid Peel Versus 40% Pyruvic Acid Peel in Epidermal Melasma.
Sheenu Goyal, Balvinder K Brar, Sumir Kumar, Amarbir Boparai, Sameer Hundal, Arnav Mehta

Indian Dermatol Online J· June 2025

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Determinants of Response to Sequential Pembrolizumab with Trastuzumab plus Platinum/5-FU in HER2-Positive Gastric Cancer: A Phase II Chemoimmunotherapy Trial.
Sung Hee Lim, Minae An, Hyuk Lee, You Jeong Heo, Byung-Hoon Min, Arnav Mehta

Clin Cancer Res· April 2025

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The Society for Immunotherapy of Cancer Perspective on Tissue-Based Technologies for Immuno-Oncology Biomarker Discovery and Application.
Anne Monette, Adriana Aguilar-Mahecha, Emre Altinmakas, Mathew G Angelos, Nima Assad, Arnav Mehta

Clin Cancer Res· February 2025

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TBK1 Targeting Is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids.
Yi Sun, Luke Maggs, Apekshya Panda, Samuel J Wright, Angelina M Cicerchia, Arnav Mehta

Cancer Immunol Res· February 2025

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Characterization of cell states in biliary tract cancers identifies mechanisms of therapeutic resistance in a phase II trial of DKN-01/nivolumab.
Ryan J Park, Milan Parikh, Leon Pappas, Moshe Sade-Feldman, Anupriya S Kulkarni, Arnav Mehta

medRxiv· October 2024

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Insights on Future Directions in Cancer Research from the AACR NextGen Stars.
Israel Cañadas, Gabriele Casirati, Kathleen E Houlahan, Kara N Maxwell, Arnav Mehta

Cancer Discov· September 2024

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Early Immune Remodeling Steers Clinical Response to First-Line Chemoimmunotherapy in Advanced Gastric Cancer.
Minae An, Arnav Mehta, Byung Hoon Min, You Jeong Heo, Samuel J Wright

Cancer Discov· May 2024

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Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy.
Jonathan H Chen, Linda T Nieman, Maxwell Spurrell, Vjola Jorgji, Liad Elmelech, Arnav Mehta

Nat Immunol· April 2024

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Association of Somatic TET2 Mutations With Giant Cell Arteritis.
Michelle L Robinette, Lachelle D Weeks, Ryan J Kramer, Mridul Agrawal, Christopher J Gibson, Arnav Mehta

Arthritis Rheumatol· March 2024

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Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy.
Or-Yam Revach, Angelina M Cicerchia, Ofir Shorer, Boryana Petrova, Seth Anderson, Arnav Mehta

bioRxiv· March 2024

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Lineage Plasticity: The New Cancer Hallmark on the Block.
Arnav Mehta, Ben Z Stanger

Cancer Res· January 2024

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Development of an artificial intelligence-derived histologic signature associated with adjuvant gemcitabine treatment outcomes in pancreatic cancer.
Vivek Nimgaonkar, Viswesh Krishna, Vrishab Krishna, Ekin Tiu, Anirudh Joshi, Arnav Mehta

Cell Rep Med· April 2023

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Spatial analysis of human lung cancer reveals organized immune hubs enriched for stem-like CD8 T cells and associated with immunotherapy response.
Jonathan H Chen, Linda T Nieman, Maxwell Spurrell, Vjola Jorgji, Peter Richieri, Arnav Mehta

bioRxiv· April 2023

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Targeting TBK1 to overcome resistance to cancer immunotherapy.
Yi Sun, Or-Yam Revach, Seth Anderson, Emily A Kessler, Clara H Wolfe, Arnav Mehta

Nature· March 2023

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Combined PD-1, BRAF and MEK inhibition in BRAF colorectal cancer: a phase 2 trial.
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Arnav Mehta

Nat Med· February 2023

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In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer.
Juan Dubrot, Peter P Du, Sarah Kate Lane-Reticker, Emily A Kessler, Audrey J Muscato, Arnav Mehta

Nat Immunol· October 2022

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Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients.
Thomas J LaSalle, Anna L K Gonye, Samuel S Freeman, Paulina Kaplonek, Irena Gushterova, Arnav Mehta

Cell Rep Med· October 2022

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