Publications by authors named "Ashley D Sanders"

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Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype.
Aino-Maija Leppä, Karen Grimes, Hyobin Jeong, Frank Y Huang, Alvaro Andrades, Ashley D Sanders

Nat Genet· December 2024

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p53 terminates the regenerative fetal-like state after colitis-associated injury.
Kimberly Hartl, Şafak Bayram, Alexandra Wetzel, Christine Harnack, Manqiang Lin, Ashley D Sanders

Sci Adv· October 2024

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Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells.
Karen Grimes, Hyobin Jeong, Amanda Amoah, Nuo Xu, Julian Niemann, Ashley D Sanders

Nat Genet· June 2024

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Functional analysis of structural variants in single cells using Strand-seq.
Hyobin Jeong, Karen Grimes, Kerstin K Rauwolf, Peter-Martin Bruch, Tobias Rausch, Ashley D Sanders

Nat Biotechnol· June 2023

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A draft human pangenome reference.
Wen-Wei Liao, Mobin Asri, Jana Ebler, Daniel Doerr, Marina Haukness, Ashley D Sanders

Nature· May 2023

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Inversion polymorphism in a complete human genome assembly.
David Porubsky, William T Harvey, Allison N Rozanski, Jana Ebler, Wolfram Höps, Ashley D Sanders

Genome Biol· April 2023

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Gaps and complex structurally variant loci in phased genome assemblies.
David Porubsky, Mitchell R Vollger, William T Harvey, Allison N Rozanski, Peter Ebert, Ashley D Sanders

Genome Res· April 2023

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Semi-automated assembly of high-quality diploid human reference genomes.
Erich D Jarvis, Giulio Formenti, Arang Rhie, Andrea Guarracino, Chentao Yang, Ashley D Sanders

Nature· November 2022

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A high-resolution map of small-scale inversions in the gibbon genome.
Ludovica Mercuri, Donato Palmisano, Alberto L'Abbate, Pietro D'Addabbo, Francesco Montinaro, Ashley D Sanders

Genome Res· October 2022

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Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders.
David Porubsky, Wolfram Höps, Hufsah Ashraf, PingHsun Hsieh, Bernardo Rodriguez-Martin, Ashley D Sanders

Cell· May 2022

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Familial long-read sequencing increases yield of de novo mutations.
Michelle D Noyes, William T Harvey, David Porubsky, Arvis Sulovari, Ruiyang Li, Ashley D Sanders

Am J Hum Genet· April 2022

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ASHLEYS: automated quality control for single-cell Strand-seq data.
Christina Gros, Ashley D Sanders, Jan O Korbel, Tobias Marschall, Peter Ebert

Bioinformatics· October 2021

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Haplotype-resolved diverse human genomes and integrated analysis of structural variation.
Peter Ebert, Peter A Audano, Qihui Zhu, Bernardo Rodriguez-Martin, David Porubsky, Ashley D Sanders

Science· April 2021

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Fully phased human genome assembly without parental data using single-cell strand sequencing and long reads.
David Porubsky, Peter Ebert, Peter A Audano, Mitchell R Vollger, William T Harvey, Ashley D Sanders

Nat Biotechnol· March 2021

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Construction of Whole Genomes from Scaffolds Using Single Cell Strand-Seq Data.
Mark Hills, Ester Falconer, Kieran O'Neill, Ashley D Sanders, Kerstin Howe

Int J Mol Sci· March 2021

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Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility.
Wesley C Warren, R Alan Harris, Marina Haukness, Ian T Fiddes, Shwetha C Murali, Ashley D Sanders

Science· December 2020

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Single-cell strand sequencing of a macaque genome reveals multiple nested inversions and breakpoint reuse during primate evolution.
Flavia Angela Maria Maggiolini, Ashley D Sanders, Colin James Shew, Arvis Sulovari, Yafei Mao

Genome Res· November 2020

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Recurrent inversion toggling and great ape genome evolution.
David Porubsky, Ashley D Sanders, Wolfram Höps, PingHsun Hsieh, Arvis Sulovari

Nat Genet· August 2020

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Improved assembly and variant detection of a haploid human genome using single-molecule, high-fidelity long reads.
Mitchell R Vollger, Glennis A Logsdon, Peter A Audano, Arvis Sulovari, David Porubsky, Ashley D Sanders

Ann Hum Genet· March 2020

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Single-cell analysis of structural variations and complex rearrangements with tri-channel processing.
Ashley D Sanders, Sascha Meiers, Maryam Ghareghani, David Porubsky, Hyobin Jeong

Nat Biotechnol· March 2020

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breakpointR: an R/Bioconductor package to localize strand state changes in Strand-seq data.
David Porubsky, Ashley D Sanders, Aaron Taudt, Maria Colomé-Tatché, Peter M Lansdorp

Bioinformatics· February 2020

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Multi-platform discovery of haplotype-resolved structural variation in human genomes.
Mark J P Chaisson, Ashley D Sanders, Xuefang Zhao, Ankit Malhotra, David Porubsky

Nat Commun· April 2019

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Genomic inversions and GOLGA core duplicons underlie disease instability at the 15q25 locus.
Flavia A M Maggiolini, Stuart Cantsilieris, Pietro D'Addabbo, Michele Manganelli, Bradley P Coe, Ashley D Sanders

PLoS Genet· March 2019

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Strand-seq enables reliable separation of long reads by chromosome via expectation maximization.
Maryam Ghareghani, David Porubskỳ, Ashley D Sanders, Sascha Meiers, Evan E Eichler

Bioinformatics· July 2018

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Dense and accurate whole-chromosome haplotyping of individual genomes.
David Porubsky, Shilpa Garg, Ashley D Sanders, Jan O Korbel, Victor Guryev

Nat Commun· November 2017

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