Publications by authors named "Ashley Pike"

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Structures of the human adult muscle-type nicotinic receptor in resting and desensitized states.
Anna Li, Ashley C W Pike, Richard Webster, Susan Maxwell, Wei-Wei Liu

Cell Rep· May 2025

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Structural basis of the mechanism and inhibition of a human ceramide synthase.
Tomas C Pascoa, Ashley C W Pike, Christofer S Tautermann, Gamma Chi, Michael Traub

Nat Struct Mol Biol· March 2025

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Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2.
Huanyu Z Li, Ashley C W Pike, Yung-Ning Chang, Dheeraj Prakaash, Zuzana Gelova

Nat Commun· January 2025

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Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist.
Gamma Chi, Dawid Jaślan, Veronika Kudrina, Julia Böck, Huanyu Li, Ashley C W Pike

Structure· August 2024

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Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2.
Huanyu Z Li, Ashley C W Pike, Irina Lotsaris, Gamma Chi, Jesper S Hansen

Nat Commun· June 2024

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Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike

Nat Commun· May 2024

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Structural characterization of human urea transporters UT-A and UT-B and their inhibition.
Gamma Chi, Larissa Dietz, Haiping Tang, Matthew Snee, Andreea Scacioc, Ashley C W Pike

Sci Adv· September 2023

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Quantitative changes in mental health measures with 3MDR treatment for Canadian military members and veterans.
Chelsea Jones, Lorraine Smith-MacDonald, Matthew Robert Graham Brown, Ashley Pike, Eric Vermetten

Brain Behav· August 2022

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New Life Through Disaster: A Thematic Analysis of Women's Experiences of Pregnancy and the 2016 Fort McMurray Wildfire.
Ashley Pike, Cynthia Mikolas, Kathleen Tompkins, Joanne Olson, David M Olson

Front Public Health· June 2022

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Workplace Reintegration Facilitator Training Program for Mental Health Literacy and Workplace Attitudes of Public Safety Personnel: Pre-Post Pilot Cohort Study.
Chelsea Jones, Lorraine Smith-MacDonald, Ashley Pike, Katherine Bright, Suzette Bremault-Phillips

JMIR Form Res· April 2022

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Neuroimaging predictors of longitudinal disability and cognition outcomes in multiple sclerosis patients: A systematic review and meta-analysis.
Ashley R Pike, George A James, Paul D Drew, Robert L Archer

Mult Scler Relat Disord· January 2022

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Companions in the Abyss: A Feasibility and Acceptability Study of an Online Therapy Group for Healthcare Providers Working During the COVID-19 Pandemic.
Lorraine Smith-MacDonald, Jaimie Lusk, Dayna Lee-Baggley, Katherine Bright, Alexa Laidlaw, Ashley Pike

Front Psychiatry· January 2022

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Resilient Parents… Resilient Communities: A Pilot Study Trialing the Bounce Back and Thrive! Resilience-Training Program With Military Families.
Cynthia Mikolas, Ashley Pike, Chelsea Jones, Lorraine Smith-MacDonald, Melina Lee

Front Psychol· July 2021

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Enhancing Resilience in Canadian Military Families and Communities: A Qualitative Analysis of the Reaching In… Reaching Out and Bounce Back and Thrive! Resiliency Skills Training Programs.
Cynthia Mikolas, Hope Winfield, Lorraine Smith-MacDonald, Ashley Pike, Chelsea Jones

Front Public Health· June 2021

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The structural basis of fatty acid elongation by the ELOVL elongases.
Laiyin Nie, Tomas C Pascoa, Ashley C W Pike, Simon R Bushell, Andrew Quigley

Nat Struct Mol Biol· June 2021

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Decision-making capacity assessment education.
Lesley Charles, Suzette Brémault-Phillips, Ashley Pike, Camelia Vokey, Tara Kilkenny

J Am Geriatr Soc· April 2021

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Virtual Reality-Based Treatment for Military Members and Veterans With Combat-Related Posttraumatic Stress Disorder: Protocol for a Multimodular Motion-Assisted Memory Desensitization and Reconsolidation Randomized Controlled Trial.
Chelsea Jones, Lorraine Smith-MacDonald, Antonio Miguel-Cruz, Ashley Pike, Marieke van Gelderen

JMIR Res Protoc· October 2020

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A lower X-gate in TASK channels traps inhibitors within the vestibule.
Karin E J Rödström, Aytuğ K Kiper, Wei Zhang, Susanne Rinné, Ashley C W Pike

Nature· June 2020

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Corrections and connection to the community: A diagnostic and service program for incarcerated adult men with FASD.
E Sharon Brintnell, Anjili S Sawhney, Patricia G Bailey, Monty Nelson, Ashley D Pike

Int J Law Psychiatry· February 2020

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Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2.
Qinrui Wang, Robin A Corey, George Hedger, Prafulla Aryal, Mariana Grieben, Ashley C W Pike

Structure· February 2020

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The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Simon R Bushell, Ashley C W Pike, Maria E Falzone, Nils J G Rorsman, Chau M Ta

Nat Commun· September 2019

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Spirituality and Moral Injury Among Military Personnel: A Mini-Review.
Suzette Brémault-Phillips, Ashley Pike, Francesca Scarcella, Terry Cherwick

Front Psychiatry· April 2019

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A pharmacological master key mechanism that unlocks the selectivity filter gate in K channels.
Marcus Schewe, Han Sun, Ümit Mert, Alexandra Mackenzie, Ashley C W Pike

Science· February 2019

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Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
Yin Yao Dong, Hua Wang, Ashley C W Pike, Stephen A Cochrane, Sadra Hamedzadeh

Cell· November 2018

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Facilitating implementation of the Decision-Making Capacity Assessment (DMCA) Model: senior leadership perspectives on the use of the National Implementation Research Network (NIRN) Model and frameworks.
Suzette Brémault-Phillips, Ashley Pike, Lesley Charles, Mary Roduta-Roberts, Aruna Mitra

BMC Res Notes· August 2018

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