Publications by authors named "Asra Mirza"

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Discovery of sulfone containing metallo-β-lactamase inhibitors with reduced bacterial cell efflux and histamine release issues.
Frank Bennett, Yuhua Huang, Shuzhi Dong, Jinlong Jiang, David Hunter, Asra Mirza

Bioorg Med Chem Lett· December 2024

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Development of a Cell-Based Reporter Potency Assay for Live Virus Vaccines.
Dengyun Sun, Brian K Meyer, Dhanvanthri S Deevi, Asra Mirza, Li He

Vaccines (Basel)· July 2024

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Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration.
Shuzhi Dong, Zhiqiang Zhao, Haiqun Tang, Guoqing Li, Jianping Pan, Asra Mirza

J Med Chem· March 2024

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Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates.
Mihirbaran Mandal, Li Xiao, Weidong Pan, Giovanna Scapin, Guoqing Li, Asra Mirza

J Med Chem· December 2022

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Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets.
Paul A Mann, Anna Müller, Kerstin A Wolff, Thierry Fischmann, Hao Wang, Asra Mirza

PLoS Pathog· May 2016

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Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors.
Stéphane L Bogen, Weidong Pan, Craig R Gibeau, Brian R Lahue, Yao Ma, Asra Mirza

ACS Med Chem Lett· March 2016

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RNA interference targeting of A1 receptor-overexpressing breast carcinoma cells leads to diminished rates of cell proliferation and induction of apoptosis.
Asra Mirza, Andrea Basso, Stuart Black, Michael Malkowski, Lia Kwee

Cancer Biol Ther· December 2005

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The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity.
Andrea D Basso, Asra Mirza, Gongjie Liu, Brian J Long, W Robert Bishop

J Biol Chem· September 2005

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Integrative genomics revealed RAI3 is a cell growth-promoting gene and a novel P53 transcriptional target.
Qun Wu, Wei Ding, Asra Mirza, Tish Van Arsdale, Iris Wei

J Biol Chem· April 2005

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Generation of p53 target database via integration of microarray and global p53 DNA-binding site analysis.
Suxing Liu, Asra Mirza, Luquan Wang

Methods Mol Biol· September 2004

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Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression.
Asra Mirza, Qun Wu, Luquan Wang, Terri McClanahan, W Robert Bishop

Oncogene· June 2003

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Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells.
Qun Wu, Paul Kirschmeier, Tish Hockenberry, Tong-Yuan Yang, Diana L Brassard, Asra Mirza

J Biol Chem· September 2002

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Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor.
Ahmed A Samatar, Luquan Wang, Asra Mirza, Sandra Koseoglu, Suxing Liu

J Biol Chem· August 2002

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Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway.
Asra Mirza, Marnie McGuirk, Tish N Hockenberry, Qun Wu, Hena Ashar

Oncogene· April 2002

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