Publications by authors named "Sandra Koseoglu"

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A Phase 3 Study of the Safety and Efficacy of Tedizolid Phosphate in Patients <12 Years of Age With Acute Bacterial Skin and Skin Structure Infections.
Rosie Mngqibisa, Oleksandr Fofanov, Carlos F Grazioso, Mario Melgar Toledo, Melissa Boddicker, Sandra Koseoglu

Pediatr Infect Dis J· June 2025

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A phase III, randomized, controlled noninferiority trial to study the efficacy and safety of imipenem/cilastatin/relebactam (IMI/REL) vs piperacillin/tazobactam (PIP/TAZ) in patients with hospital-acquired bacterial pneumonia (HABP) or ventilator-associated bacterial pneumonia (VABP).
Junjie Li, Feng Wei, Peng Xiang, Zhengang Tang, Lianshu Ding, Sandra Koseoglu

Int J Infect Dis· April 2025

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A phase 3, multicenter, randomized, double-blind, active-comparator-controlled study to evaluate the safety, tolerability, and immunogenicity of a 4-dose regimen of V114, a 15-valent pneumococcal conjugate vaccine, in healthy infants (PNEU-PED).
Robert Lupinacci, Richard Rupp, Orasri Wittawatmongkol, Jake Jones, Jeffrey Quinones, Sandra Koseoglu

Vaccine· January 2023

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Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO Inhibitor.
Mihirbaran Mandal, Zheng Tan, Christina Madsen-Duggan, Alexei V Buevich, John P Caldwell, Sandra Koseoglu

J Med Chem· May 2017

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Benzimidazole analogs as WTA biosynthesis inhibitors targeting methicillin resistant Staphylococcus aureus.
Shu-Wei Yang, Jianping Pan, Christine Yang, Marc Labroli, Weidong Pan, Sandra Koseoglu

Bioorg Med Chem Lett· October 2016

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Discovery of potent wall teichoic acid early stage inhibitors.
Marc A Labroli, John P Caldwell, Christine Yang, Sang Ho Lee, Hao Wang, Sandra Koseoglu

Bioorg Med Chem Lett· August 2016

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TarO-specific inhibitors of wall teichoic acid biosynthesis restore β-lactam efficacy against methicillin-resistant staphylococci.
Sang Ho Lee, Hao Wang, Marc Labroli, Sandra Koseoglu, Paul Zuck

Sci Transl Med· March 2016

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Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis.
Paul A Mann, Catherine A McLellan, Sandra Koseoglu, Qian Si, Elena Kuzmin

ACS Infect Dis· January 2015

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AKT1, AKT2 and AKT3-dependent cell survival is cell line-specific and knockdown of all three isoforms selectively induces apoptosis in 20 human tumor cell lines.
Sandra Koseoglu, Zhuomei Lu, Chandra Kumar, Paul Kirschmeier, Jun Zou

Cancer Biol Ther· May 2007

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Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors.
Terrill McClanahan, Sandra Koseoglu, Kathleen Smith, Jeffrey Grein, Eric Gustafson

Cancer Biol Ther· April 2006

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Development of a fluorescence polarization bead-based coupled assay to target different activity/conformation states of a protein kinase.
Zhuomei Lu, Zhizhang Yin, Linda James, Rosalinda Syto, Jill M Stafford, Sandra Koseoglu

J Biomol Screen· June 2004

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Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor.
Ahmed A Samatar, Luquan Wang, Asra Mirza, Sandra Koseoglu, Suxing Liu

J Biol Chem· August 2002

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