Publications by authors named "Assaf Alon"

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Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application.
Lisa D J Schiffelers, Yonas M Tesfamariam, Lea-Marie Jenster, Stefan Diehl, Sophie C Binder, Assaf Alon

Nat Commun· September 2024

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AlphaFold2 structures guide prospective ligand discovery.
Jiankun Lyu, Nicholas Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang

Science· June 2024

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AlphaFold2 structures template ligand discovery.
Jiankun Lyu, Nicholas Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang

bioRxiv· March 2024

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The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination.
Yongqiang Gao, Rocio Del Carmen Barajas-Ornelas, Jeremy D Amon, Fernando H Ramírez-Guadiana, Assaf Alon

Genes Dev· May 2022

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The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3.
Uthman Okalang, Bar Mualem Bar-Ner, K Shanmugha Rajan, Nehemya Friedman, Saurav Aryal, Assaf Alon

mBio· December 2021

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Structures of the σ receptor enable docking for bioactive ligand discovery.
Assaf Alon, Jiankun Lyu, Joao M Braz, Tia A Tummino, Veronica Craik

Nature· December 2021

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Dormant spores sense amino acids through the B subunits of their germination receptors.
Lior Artzi, Assaf Alon, Kelly P Brock, Anna G Green, Amy Tam

Nat Commun· November 2021

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Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2.
Tia A Tummino, Veronica V Rezelj, Benoit Fischer, Audrey Fischer, Matthew J O'Meara, Assaf Alon

Science· July 2021

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Phospholipidosis is a shared mechanism underlying the antiviral activity of many repurposed drugs against SARS-CoV-2.
Tia A Tummino, Veronica V Rezelj, Benoit Fischer, Audrey Fischer, Matthew J O'Meara, Assaf Alon

bioRxiv· March 2021

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COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms.
Robert W Malone, Philip Tisdall, Philip Fremont-Smith, Yongfeng Liu, Xi-Ping Huang, Assaf Alon, Jill Glasspool-Malone

Front Pharmacol· March 2021

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COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms.
Robert W Malone, Philip Tisdall, Philip Fremont-Smith, Yongfeng Liu, Xi-Ping Huang, Assaf Alon, Jill Glasspool-Malone

Res Sq· August 2020

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cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures.
Gabriel Javitt, Iris Grossman-Haham, Assaf Alon, Efrat Resnick, Yael Mutsafi

Protein Sci· January 2019

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Structural Perspectives on Sigma-1 Receptor Function.
Assaf Alon, Hayden Schmidt, Sanduo Zheng, Andrew C Kruse

Adv Exp Med Biol· September 2017

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Identification of the gene that codes for the σ receptor.
Assaf Alon, Hayden R Schmidt, Michael D Wood, James J Sahn, Stephen F Martin

Proc Natl Acad Sci U S A· July 2017

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AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences.
Gideon D Lapidoth, Dror Baran, Gabriele M Pszolla, Christoffer Norn, Assaf Alon

Proteins· August 2015

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An inhibitory antibody blocks the first step in the dithiol/disulfide relay mechanism of the enzyme QSOX1.
Iris Grossman, Assaf Alon, Tal Ilani, Deborah Fass

J Mol Biol· November 2013

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A secreted disulfide catalyst controls extracellular matrix composition and function.
Tal Ilani, Assaf Alon, Iris Grossman, Ben Horowitz, Elena Kartvelishvily

Science· July 2013

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Exploring ORFan domains in giant viruses: structure of mimivirus sulfhydryl oxidase R596.
Motti Hakim, Daria Ezerina, Assaf Alon, Ohad Vonshak, Deborah Fass

PLoS One· May 2013

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Phylogenetics and enzymology of plant quiescin sulfhydryl oxidase.
Keren Limor-Waisberg, Assaf Alon, Tevie Mehlman, Deborah Fass

FEBS Lett· November 2012

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The dynamic disulphide relay of quiescin sulphydryl oxidase.
Assaf Alon, Iris Grossman, Yair Gat, Vamsi K Kodali, Frank DiMaio

Nature· August 2012

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Improved molecular replacement by density- and energy-guided protein structure optimization.
Frank DiMaio, Thomas C Terwilliger, Randy J Read, Alexander Wlodawer, Gustav Oberdorfer, Assaf Alon

Nature· May 2011

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QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains.
Assaf Alon, Erin J Heckler, Colin Thorpe, Deborah Fass

FEBS Lett· April 2010

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Human quiescin-sulfhydryl oxidase, QSOX1: probing internal redox steps by mutagenesis.
Erin J Heckler, Assaf Alon, Deborah Fass, Colin Thorpe

Biochemistry· April 2008

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