Publications by authors named "Astrid D Haase"

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Pachytene piRNAs define a conserved program of meiotic gene regulation: Pachytene piRNAs directly regulate select mRNAs by and RNAi-like mechanism, establishing a regulatory paradigm of mammalian meiosis.
Zuzana Loubalova, Franziska Ahrend, Daniel Stoyko, Rachel Cosby, Sherry Ralls, Astrid D Haase

bioRxiv· November 2025

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Protocol for assembling, prioritizing, and characterizing piRNA clusters using the piRNA Cluster Builder.
Franziska Ahrend, Parthena Konstantinidou, Zuzana Loubalova, Yuejun Wang, Hernan Lorenzi, Astrid D Haase

STAR Protoc· June 2025

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A deficiency screen identifies genomic regions critical for sperm head-tail connection.
Brian J Galletta, Parthena Konstantinidou, Astrid D Haase, Nasser M Rusan

G3 (Bethesda)· February 2025

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Activity of the mammalian DNA transposon piggyBat from Myotis lucifugus is restricted by its own transposon ends.
Alison B Hickman, Laurie Lannes, Christopher M Furman, Christina Hong, Lidiya Franklin, Astrid D Haase

Nat Commun· January 2025

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Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes.
Miguel Vasconcelos Almeida, Moritz Blumer, Chengwei Ulrika Yuan, Pío Sierra, Jonathan L Price, Astrid D Haase

Genome Biol· January 2025

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PIWI-interacting RNAs: who, what, when, where, why, and how.
Astrid D Haase, Rene F Ketting, Eric C Lai, Ronald P van Rij, Mikiko Siomi

EMBO J· November 2024

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Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role.
Dimitrios G Anastasakis, Maria Apostolidi, Khalid A Garman, Ahsan H Polash, Mubarak I Umar, Astrid D Haase

Mol Cell· October 2024

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A comparative roadmap of PIWI-interacting RNAs across seven species reveals insights into de novo piRNA-precursor formation in mammals.
Parthena Konstantinidou, Zuzana Loubalova, Franziska Ahrend, Aleksandr Friman, Miguel Vasconcelos Almeida, Astrid D Haase

Cell Rep· October 2024

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A deficiency screen identifies genomic regions critical for sperm head-tail connection.
Brian J Galletta, Parthena Konstantinidou, Astrid D Haase, Nasser M Rusan

bioRxiv· August 2024

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Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes.
Miguel Vasconcelos Almeida, Moritz Blumer, Chengwei Ulrika Yuan, Pío Sierra, Jonathan L Price, Astrid D Haase

bioRxiv· April 2024

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Themes and variations on piRNA-guided transposon control.
Zuzana Loubalova, Parthena Konstantinidou, Astrid D Haase

Mob DNA· September 2023

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CRISPR-Cas9 Genome Editing and Rapid Selection of Cell Pools.
Daniel Stoyko, Timothy O, Adrianna Hernandez, Parthena Konstantinidou, Qingcai Meng, Astrid D Haase

Curr Protoc· December 2022

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Functional editing of endogenous genes through rapid selection of cell pools (Rapid generation of endogenously tagged genes in Drosophila ovarian somatic sheath cells).
Qingcai Meng, Daniel Stoyko, Celine Marlin Andrews, Parthena Konstantinidou, Pavol Genzor, Astrid D Haase

Nucleic Acids Res· August 2022

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Transcriptomics, regulatory syntax, and enhancer identification in mesoderm-induced ESCs at single-cell resolution.
Mamduh Khateb, Jelena Perovanovic, Kyung Dae Ko, Kan Jiang, Xuesong Feng, Astrid D Haase

Cell Rep· August 2022

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Hierarchical length and sequence preferences establish a single major piRNA 3'-end.
Daniel Stoyko, Pavol Genzor, Astrid D Haase

iScience· June 2022

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An introduction to PIWI-interacting RNAs (piRNAs) in the context of metazoan small RNA silencing pathways.
Astrid D Haase

RNA Biol· January 2022

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Cellular abundance shapes function in piRNA-guided genome defense.
Pavol Genzor, Parthena Konstantinidou, Daniel Stoyko, Amirhossein Manzourolajdad, Celine Marlin Andrews, Astrid D Haase

Genome Res· November 2021

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A non-radioactive, improved PAR-CLIP and small RNA cDNA library preparation protocol.
Dimitrios G Anastasakis, Alexis Jacob, Parthena Konstantinidou, Kazuyuki Meguro, Duncan Claypool, Astrid D Haase

Nucleic Acids Res· May 2021

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Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas.
Alison B Hickman, Shweta Kailasan, Pavol Genzor, Astrid D Haase, Fred Dyda

Elife· January 2020

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PiRNAs Rise to Rescue Koalas.
Astrid D Haase, Todd S Macfarlan

Cell· October 2019

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Aberrant expression of select piRNA-pathway genes does not reactivate piRNA silencing in cancer cells.
Pavol Genzor, Seth C Cordts, Neha V Bokil, Astrid D Haase

Proc Natl Acad Sci U S A· June 2019

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Decoding the 5' nucleotide bias of PIWI-interacting RNAs.
Chad B Stein, Pavol Genzor, Sanga Mitra, Alexandra R Elchert, Jonathan J Ipsaro, Astrid D Haase

Nat Commun· February 2019

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Argonaute-miRNA Complexes Silence Target mRNAs in the Nucleus of Mammalian Stem Cells.
Aishe A Sarshad, Aster H Juan, Ana Iris Correa Muler, Dimitrios G Anastasakis, Xiantao Wang, Astrid D Haase

Mol Cell· September 2018

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A Small RNA-Based Immune System Defends Germ Cells against Mobile Genetic Elements.
Astrid D Haase

Stem Cells Int· December 2015

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Dephosphorylation of tyrosine 393 in argonaute 2 by protein tyrosine phosphatase 1B regulates gene silencing in oncogenic RAS-induced senescence.
Ming Yang, Astrid D Haase, Fang-Ke Huang, Gérald Coulis, Keith D Rivera

Mol Cell· September 2014

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