Publications by authors named "Attila D Kovacs"

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Acidified drinking water improves motor function, prevents tremors and changes disease trajectory in Cln2 mice, a model of late infantile Batten disease.
Attila D Kovács, Jose L Gonzalez Hernandez, David A Pearce

Sci Rep· November 2023

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Acidified drinking water attenuates motor deficits and brain pathology in a mouse model of a childhood neurodegenerative disorder.
Attila D Kovács, Logan M Langin, Jose L Gonzalez Hernandez, David A Pearce

Sci Rep· May 2022

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The acidified drinking water-induced changes in the behavior and gut microbiota of wild-type mice depend on the acidification mode.
Brandon Whipple, Jennifer Agar, Jing Zhao, David A Pearce, Attila D Kovács

Sci Rep· February 2021

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Comparative analysis of the gut microbiota composition in the Cln1 and Cln2 mouse models of Batten disease and in three wild-type mouse strains.
Camille Parker, Jing Zhao, David A Pearce, Attila D Kovács

Arch Microbiol· January 2021

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A tailored Cln3 mouse model for testing therapeutic interventions in CLN3 Batten disease.
Logan Langin, Tyler B Johnson, Attila D Kovács, David A Pearce, Jill M Weimer

Sci Rep· June 2020

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Changes in motor behavior, neuropathology, and gut microbiota of a Batten disease mouse model following administration of acidified drinking water.
Tyler B Johnson, Logan M Langin, Jing Zhao, Jill M Weimer, David A Pearce

Sci Rep· October 2019

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Lack of specificity of antibodies raised against CLN3, the lysosomal/endosomal transmembrane protein mutated in juvenile Batten disease.
Tarah Nelson, David A Pearce, Attila D Kovács

Biosci Rep· December 2017

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Role of the Lysosomal Membrane Protein, CLN3, in the Regulation of Cathepsin D Activity.
Jaime Cárcel-Trullols, Attila D Kovács, David A Pearce

J Cell Biochem· November 2017

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Genetic ataxia telangiectasia porcine model phenocopies the multisystemic features of the human disease.
Rosanna Beraldi, David K Meyerholz, Alexei Savinov, Attila D Kovács, Jill M Weimer

Biochim Biophys Acta Mol Basis Dis· November 2017

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A tailored mouse model of CLN2 disease: A nonsense mutant for testing personalized therapies.
Ryan D Geraets, Logan M Langin, Jacob T Cain, Camille M Parker, Rosanna Beraldi, Attila D Kovacs

PLoS One· September 2017

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Decreased sensitivity of palmitoyl protein thioesterase 1-deficient neurons to chemical anoxia.
Meredith Meyer, Attila D Kovács, David A Pearce

Metab Brain Dis· February 2017

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Antigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosis.
Samantha L Hersrud, Attila D Kovács, David A Pearce

Biochim Biophys Acta· July 2016

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Tissue-specific variation in nonsense mutant transcript level and drug-induced read-through efficiency in the Cln1(R151X) mouse model of INCL.
Vaughn Thada, Jake N Miller, Attila D Kovács, David A Pearce

J Cell Mol Med· February 2016

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A novel porcine model of ataxia telangiectasia reproduces neurological features and motor deficits of human disease.
Rosanna Beraldi, Chun-Hung Chan, Christopher S Rogers, Attila D Kovács, David K Meyerholz

Hum Mol Genet· November 2015

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Cell biology of the NCL proteins: What they do and don't do.
Jaime Cárcel-Trullols, Attila D Kovács, David A Pearce

Biochim Biophys Acta· October 2015

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Abnormally increased surface expression of AMPA receptors in the cerebellum, cortex and striatum of Cln3(-/-) mice.
Attila D Kovács, Caitlin Hof, David A Pearce

Neurosci Lett· October 2015

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Finding the most appropriate mouse model of juvenile CLN3 (Batten) disease for therapeutic studies: the importance of genetic background and gender.
Attila D Kovács, David A Pearce

Dis Model Mech· April 2015

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The novel Cln1(R151X) mouse model of infantile neuronal ceroid lipofuscinosis (INCL) for testing nonsense suppression therapy.
Jake N Miller, Attila D Kovács, David A Pearce

Hum Mol Genet· January 2015

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The human synaptic vesicle protein, SV2A, functions as a galactose transporter in Saccharomyces cerevisiae.
Marianna Madeo, Attila D Kovács, David A Pearce

J Biol Chem· November 2014

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Osmotic stress changes the expression and subcellular localization of the Batten disease protein CLN3.
Amanda Getty, Attila D Kovács, Tímea Lengyel-Nelson, Andrew Cardillo, Caitlin Hof

PLoS One· February 2014

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Location- and sex-specific differences in weight and motor coordination in two commonly used mouse strains.
Attila D Kovács, David A Pearce

Sci Rep· September 2013

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Seizure susceptibility, phenotype, and resultant growth delay in the nclf and mnd mouse models of neuronal ceroid lipofuscinoses.
Elizabeth Kriscenski-Perry, Attila D Kovács, David A Pearce

J Child Neurol· September 2013

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Treatment of the Ppt1(-/-) mouse model of infantile neuronal ceroid lipofuscinosis with the N-methyl-D-aspartate (NMDA) receptor antagonist memantine.
Rozzy Finn, Attila D Kovács, David A Pearce

J Child Neurol· September 2013

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Age-dependent therapeutic effect of memantine in a mouse model of juvenile Batten disease.
Attila D Kovács, Angelika Saje, Andrew Wong, Serena Ramji, Jonathan D Cooper

Neuropharmacology· October 2012

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Altered glutamate receptor function in the cerebellum of the Ppt1-/- mouse, a murine model of infantile neuronal ceroid lipofuscinosis.
Rozzy Finn, Attila D Kovács, David A Pearce

J Neurosci Res· February 2012

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