Publications by authors named "Tyler B Johnson"

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NF1 miniswine model the cellular disruptions and behavioral presentations of NF1-associated cognitive and motor impairment.
Vicki J Swier, Katherine A White, Pedro L Negrão de Assis, Tyler B Johnson, Hannah G Leppert

Clin Transl Sci· June 2024

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Sortilin inhibition treats multiple neurodegenerative lysosomal storage disorders.
Hannah G Leppert, Joelle T Anderson, Kaylie J Timm, Cristina Davoli, Melissa A Pratt, Tyler B Johnson

bioRxiv· September 2023

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A novel porcine model of CLN3 Batten disease recapitulates clinical phenotypes.
Vicki J Swier, Katherine A White, Tyler B Johnson, Xiaojun Wang, Jimin Han

Dis Model Mech· August 2023

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Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease.
Tyler B Johnson, Jon J Brudvig, Shibi Likhite, Melissa A Pratt, Katherine A White

Front Genet· March 2023

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Sex-split analysis of pathology and motor-behavioral outcomes in a mouse model of CLN8-Batten disease reveals an increased disease burden and trajectory in female Cln8 mice.
Andrew D Holmes, Katherine A White, Melissa A Pratt, Tyler B Johnson, Shibi Likhite

Orphanet J Rare Dis· November 2022

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A Novel Porcine Model of CLN2 Batten Disease that Recapitulates Patient Phenotypes.
Vicki J Swier, Katherine A White, Tyler B Johnson, Jessica C Sieren, Hans J Johnson

Neurotherapeutics· October 2022

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Glycerophosphoinositol is Elevated in Blood Samples From pigs, Mice, and CLN3-Affected Individuals.
Jon J Brudvig, Vicki J Swier, Tyler B Johnson, Jacob C Cain, Melissa Pratt

Biomark Insights· June 2022

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Transmembrane Batten Disease Proteins Interact With a Shared Network of Vesicle Sorting Proteins, Impacting Their Synaptic Enrichment.
Mitchell J Rechtzigel, Brandon L Meyerink, Hannah Leppert, Tyler B Johnson, Jacob T Cain

Front Neurosci· May 2022

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Intracranial delivery of AAV9 gene therapy partially prevents retinal degeneration and visual deficits in CLN6-Batten disease mice.
Katherine A White, Hemanth R Nelvagal, Timothy A Poole, Bin Lu, Tyler B Johnson

Mol Ther Methods Clin Dev· March 2021

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A human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor-RPE interface.
Cynthia Tang, Jimin Han, Sonal Dalvi, Kannan Manian, Lauren Winschel, Tyler B Johnson

Commun Biol· February 2021

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AAV9 Gene Therapy Increases Lifespan and Treats Pathological and Behavioral Abnormalities in a Mouse Model of CLN8-Batten Disease.
Tyler B Johnson, Katherine A White, Jon J Brudvig, Jacob T Cain, Logan Langin

Mol Ther· January 2021

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Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease.
Jessica L Centa, Francine M Jodelka, Anthony J Hinrich, Tyler B Johnson, Joseph Ochaba

Nat Med· September 2020

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A multimodal approach to identify clinically relevant biomarkers to comprehensively monitor disease progression in a mouse model of pediatric neurodegenerative disease.
Tyler B Johnson, Jon J Brudvig, Kimmo K Lehtimäki, Jacob T Cain, Katherine A White

Prog Neurobiol· June 2020

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A tailored Cln3 mouse model for testing therapeutic interventions in CLN3 Batten disease.
Logan Langin, Tyler B Johnson, Attila D Kovács, David A Pearce, Jill M Weimer

Sci Rep· June 2020

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Author Correction: Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1.
Tyler B Johnson, Keegan Mechels, Ruthellen H Anderson, Jacob T Cain, David A Sturdevant

Sci Rep· April 2020

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Preparation, FPLC Purification and LC-FT-ICR-MS of Proteins.
Tyler B Johnson, Jiri Adamec, Paul Blum

Bio Protoc· April 2020

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Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease.
Jacob T Cain, Shibi Likhite, Katherine A White, Derek J Timm, Samantha S Davis, Tyler B Johnson

Mol Ther· October 2019

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Changes in motor behavior, neuropathology, and gut microbiota of a Batten disease mouse model following administration of acidified drinking water.
Tyler B Johnson, Logan M Langin, Jing Zhao, Jill M Weimer, David A Pearce

Sci Rep· October 2019

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Therapeutic landscape for Batten disease: current treatments and future prospects.
Tyler B Johnson, Jacob T Cain, Katherine A White, Denia Ramirez-Montealegre, David A Pearce

Nat Rev Neurol· March 2019

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Tracking sex-dependent differences in a mouse model of CLN6-Batten disease.
McKayla J Poppens, Jacob T Cain, Tyler B Johnson, Katherine A White, Samantha S Davis

Orphanet J Rare Dis· January 2019

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Secretion and fusion of biogeochemically active archaeal membrane vesicles.
Tyler B Johnson, Collin Mach, Ryan Grove, Robert Kelly, Kevin Van Cott

Geobiology· November 2018

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Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1.
Tyler B Johnson, Keegan Mechels, Ruthellen H Anderson, Jacob T Cain, David A Sturdevant

Sci Rep· November 2018

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Methylenetetrahydrofolate Reductase A1298C Polymorphism and Major Depressive Disorder.
Kevin Cho, Zubair M Amin, Jie An, Kerry Anne Rambaran, Tyler B Johnson

Cureus· October 2017

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The Current Landscape of Marijuana and Pharmacogenetics.
Kerry Anne Rambaran, Michael Chu, Tyler B Johnson, Saeed K Alzghari

Cureus· July 2017

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