Publications by authors named "Avipsa Ghosh"

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Subtype selective PET imaging of PARP1 binding in non-human primates, healthy volunteers and patients with glioblastoma using [11C]AZ14193391.
Zsolt Cselényi, Aurelija Jucaite, Giuseppe Stragliotto, Jiri Bartek, Peter Johnström, Avipsa Ghosh

Neuro Oncol· December 2025

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Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome.
Avipsa Ghosh, Afshan Ahmed, Konstantina Amoiradaki, Amber Y S Balazs, Bernard Barlaam

J Med Chem· September 2025

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Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}--methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor.
Jeffrey W Johannes, Amber Y S Balazs, Derek Barratt, Michal Bista, Matthew D Chuba, Avipsa Ghosh

J Med Chem· December 2024

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Photoredox-Mediated, Nickel-Catalyzed Trifluoromethylthiolation of Aryl and Heteroaryl Iodides.
Christopher S Gravatt, Jeffrey W Johannes, Eric R King, Avipsa Ghosh

J Org Chem· July 2022

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Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}--methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs.
Jeffrey W Johannes, Amber Balazs, Derek Barratt, Michal Bista, Matthew D Chuba, Avipsa Ghosh

J Med Chem· October 2021

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Organophosphorus-Catalyzed Deoxygenation of Sulfonyl Chlorides: Electrophilic (Fluoroalkyl)sulfenylation by P /P =O Redox Cycling.
Avipsa Ghosh, Morgan Lecomte, Shin-Ho Kim-Lee, Alexander T Radosevich

Angew Chem Int Ed Engl· February 2019

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A Biphilic Phosphetane Catalyzes N-N Bond-Forming Cadogan Heterocyclization via P/P═O Redox Cycling.
Trevor V Nykaza, Tyler S Harrison, Avipsa Ghosh, Rachel A Putnik, Alexander T Radosevich

J Am Chem Soc· May 2017

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Enantioselective Model Synthesis and Progress toward the Putative Structure of Yuremamine.
Avipsa Ghosh, David T Bainbridge, Levi M Stanley

J Org Chem· September 2016

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Enantioselective synthesis of polycyclic nitrogen heterocycles by Rh-catalyzed alkene hydroacylation: constructing six-membered rings in the absence of chelation assistance.
Xiang-Wei Du, Avipsa Ghosh, Levi M Stanley

Org Lett· August 2014

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Enantioselective hydroacylation of N-vinylindole-2-carboxaldehydes.
Avipsa Ghosh, Levi M Stanley

Chem Commun (Camb)· March 2014

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