Publications by authors named "Avis Hains"

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First-in-human phase 1 trial evaluating safety, pharmacokinetics, and pharmacodynamics of NLRP3 inflammasome inhibitor, GDC-2394, in healthy volunteers.
Fei Tang, Rebecca Kunder, Tom Chu, Avis Hains, Allen Nguyen

Clin Transl Sci· September 2023

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A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS.
Jonathan S Katz, Jeffrey D Rothstein, Merit E Cudkowicz, Angela Genge, Björn Oskarsson, Avis B Hains

Ann Clin Transl Neurol· January 2022

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Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel Na1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers.
Michael E Rothenberg, Michael Tagen, Jae H Chang, Janel Boyce-Rustay, Michel Friesenhahn, Avis Hains

Clin Drug Investig· September 2019

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Correction to: Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel Na1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers.
Michael E Rothenberg, Michael Tagen, Jae H Chang, Janel Boyce-Rustay, Michel Friesenhahn, Avis Hains

Clin Drug Investig· September 2019

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Chronic Stimulation of Alpha-2A-Adrenoceptors With Guanfacine Protects Rodent Prefrontal Cortex Dendritic Spines and Cognition From the Effects of Chronic Stress.
Avis Brennan Hains, Yoko Yabe, Amy F T Arnsten

Neurobiol Stress· January 2015

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Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress.
Avis Brennan Hains, Mai Anh T Vu, Paul K Maciejewski, Christopher H van Dyck, Melissa Gottron

Proc Natl Acad Sci U S A· October 2009

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Neuropathic pain memory is maintained by Rac1-regulated dendritic spine remodeling after spinal cord injury.
Andrew M Tan, Severine Stamboulian, Yu-Wen Chang, Peng Zhao, Avis B Hains, Bryan C Hains

J Neurosci· December 2008

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Molecular mechanisms of stress-induced prefrontal cortical impairment: implications for mental illness.
Avis B Hains, Amy F T Arnsten

Learn Mem· August 2008

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