Publications by authors named "Axel Ullrich"

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Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach.
Zhiguang Xiao, Bianca Sperl, Silvia Gärtner, Tatiana Nedelko, Elvira Stacher-Priehse, Axel Ullrich

Oncotarget· August 2021

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Retraction Notice to: The Cancer-Associated FGFR4-G388R Polymorphism Enhances Pancreatic Insulin Secretion and Modifies the Risk of Diabetes.
Shereen Ezzat, Lei Zheng, Jose C Florez, Norbert Stefan, Thomas Mayr, Axel Ullrich

Cell Metab· October 2020

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The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet.
Stefan Z Lutz, Anita M Hennige, Andreas Peter, Marketa Kovarova, Charisis Totsikas, Axel Ullrich

J Clin Endocrinol Metab· June 2019

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Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach.
Zhiguang Xiao, Bianca Sperl, Silvia Gärtner, Tatiana Nedelko, Elvira Stacher-Priehse, Axel Ullrich

Oncotarget· April 2019

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Discovery of N-[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides as Novel AXL Kinase Inhibitors.
István Szabadkai, Robert Torka, Rita Garamvölgyi, Ferenc Baska, Pál Gyulavári, Axel Ullrich

J Med Chem· July 2018

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Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans.
Stefan Z Lutz, Mathias Falcenberg, Fausto Machicao, Andreas Peter, Martin Kächele, Axel Ullrich

Sci Rep· May 2018

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GAS6-expressing and self-sustaining cancer cells in 3D spheroids activate the PDK-RSK-mTOR pathway for survival and drug resistance.
Christine Baumann, Axel Ullrich, Robert Torka

Mol Oncol· October 2017

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Sunitinib specifically augments glucose-induced insulin secretion.
Stefan Z Lutz, Axel Ullrich, Hans-Ulrich Häring, Susanne Ullrich, Felicia Gerst

Cell Signal· August 2017

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Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients.
Zhiguang Xiao, Silvia Gaertner, Alicia Morresi-Hauf, Rebecca Genzel, Thomas Duell, Axel Ullrich

Neoplasia· May 2017

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Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases.
Ann-Katrin Sommer, Adam Hermawan, Frauke Martina Mickler, Bojan Ljepoja, Pjotr Knyazev, Axel Ullrich

Oncotarget· August 2016

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Membrane-proximal binding of STAT3 revealed by cancer-associated receptor variants.
Vijay K Ulaganathan, Axel Ullrich

Mol Cell Oncol· May 2016

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Inhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS-777607 reduces glioblastoma growth, migration, and invasion in vitro and in vivo.
Julia Onken, Robert Torka, Sören Korsing, Josefine Radke, Irina Krementeskaia, Axel Ullrich

Oncotarget· March 2016

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Novel compounds reducing IRS-1 serine phosphorylation for treatment of diabetes.
Laura Simon-Szabó, Márton Kokas, Zoltán Greff, Sándor Boros, Péter Bánhegyi, Axel Ullrich

Bioorg Med Chem Lett· January 2016

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Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy.
Alexander Grabner, Ansel P Amaral, Karla Schramm, Saurav Singh, Alexis Sloan, Axel Ullrich

Cell Metab· December 2015

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Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site.
Vijay K Ulaganathan, Bianca Sperl, Ulf R Rapp, Axel Ullrich

Nature· December 2015

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Combined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cells.
Kinga Pénzes, Christine Baumann, István Szabadkai, László Orfi, György Kéri, Axel Ullrich

Cancer Biol Ther· August 2015

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Erk2 but not Erk1 regulates crosstalk between Met and EGFR in squamous cell carcinoma cell lines.
Simone Gusenbauer, Emanuele Zanucco, Pjotr Knyazev, Axel Ullrich

Mol Cancer· March 2015

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Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status.
Zhiguang Xiao, Bianca Sperl, Axel Ullrich, Pjotr Knyazev

Oncotarget· December 2014

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Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepatocellular carcinoma.
Han Kiat Ho, Boon Tin Chua, Winnie Wong, Kah Suan Lim, Vivian Teo, Axel Ullrich

Mol Oncol· October 2014

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PTK7 as a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients, and resistance to anthracycline drugs.
Beyhan Ataseven, Angela Gunesch, Wolfgang Eiermann, Ronald E Kates, Bernhard Högel, Axel Ullrich

Onco Targets Ther· October 2014

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Elimination of B-RAF in oncogenic C-RAF-expressing alveolar epithelial type II cells reduces MAPK signal intensity and lung tumor growth.
Emanuele Zanucco, Nefertiti El-Nikhely, Rudolf Götz, Katharina Weidmann, Verena Pfeiffer, Axel Ullrich

J Biol Chem· September 2014

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[Development and biochemical characterization of EGFR/c-Met dual inhibitors].
Bálint Szokol, Pál Gyulavári, Ferenc Baska, Kurkó Ibolya, Zoltán Greff, Ullrich Axel

Acta Pharm Hung· April 2014

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Activation of HER3 interferes with antitumor effects of Axl receptor tyrosine kinase inhibitors: suggestion of combination therapy.
Robert Torka, Kinga Pénzes, Simone Gusenbauer, Christine Baumann, István Szabadkai, Axel Ullrich

Neoplasia· April 2014

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Discovery and Biological Evaluation of Novel Dual EGFR/c-Met Inhibitors.
Bálint Szokol, Pál Gyulavári, Ibolya Kurkó, Ferenc Baska, Csaba Szántai-Kis, Axel Ullrich

ACS Med Chem Lett· April 2014

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The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.
Magdalena Paolino, Axel Choidas, Stephanie Wallner, Blanka Pranjic, Iris Uribesalgo, Axel Ullrich

Nature· March 2014

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