Publications by authors named "Felicia Gerst"

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Prevention of type 2 diabetes through prediabetes remission without weight loss.
Arvid Sandforth, Elsa Vazquez Arreola, Robert L Hanson, Nicolai J Wewer Albrechtsen, Jens Juul Holst, Felicia Gerst

Nat Med· October 2025

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Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets.
Estela Lorza-Gil, Gabriele Kaiser, Christopher Carlein, Markus D A Hoffmann, Gabriele M König, Felicia Gerst

Diabetologia· August 2023

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Extracellular Matrix Expression in Human Pancreatic Fat Cells of Patients with Normal Glucose Regulation, Prediabetes and Type 2 Diabetes.
Dorothea Siegel-Axel, Morgana Barroso Oquendo, Felicia Gerst, Falko Fend, Robert Wagner

Int J Mol Sci· July 2023

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Effects of adrenergic-stimulated lipolysis and cytokine production on in vitro mouse adipose tissue-islet interactions.
Morgana Barroso Oquendo, Estela Lorza-Gil, David Juarez-Lopez, Robert Wagner, Andreas L Birkenfeld, Felicia Gerst

Sci Rep· September 2022

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Metabolic implications of pancreatic fat accumulation.
Robert Wagner, Sabine S Eckstein, Hajime Yamazaki, Felicia Gerst, Jürgen Machann

Nat Rev Endocrinol· January 2022

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Author Correction: Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing.
Francesco Volta, M Julia Scerbo, Anett Seelig, Robert Wagner, Nils O'Brien, Felicia Gerst

Nat Commun· August 2021

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The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells.
Felicia Gerst, Elisabeth Kemter, Estela Lorza-Gil, Gabriele Kaiser, Ann-Kathrin Fritz

Diabetologia· June 2021

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Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity.
Morgana Barroso Oquendo, Dorothea Siegel-Axel, Felicia Gerst, Estela Lorza-Gil, Anja Moller

Am J Physiol Cell Physiol· June 2021

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Pancreatic Steatosis Associates With Impaired Insulin Secretion in Genetically Predisposed Individuals.
Róbert Wagner, Benjamin Assad Jaghutriz, Felicia Gerst, Morgana Barroso Oquendo, Jürgen Machann

J Clin Endocrinol Metab· November 2020

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Glucose Responsiveness of β-Cells Depends on Fatty Acids.
Felicia Gerst, Christine Singer, Katja Noack, Dunia Graf, Gabriele Kaiser

Exp Clin Endocrinol Diabetes· October 2020

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FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells.
Estela Lorza-Gil, Gabriele Kaiser, Elisabeth Rexen Ulven, Gabriele M König, Felicia Gerst

Sci Rep· October 2020

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Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing.
Francesco Volta, M Julia Scerbo, Anett Seelig, Robert Wagner, Nils O'Brien, Felicia Gerst

Nat Commun· December 2019

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Pancreatic adipocytes mediate hypersecretion of insulin in diabetes-susceptible mice.
Charline Quiclet, Nicole Dittberner, Anneke Gässler, Mandy Stadion, Felicia Gerst

Metabolism· August 2019

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What role do fat cells play in pancreatic tissue?
Felicia Gerst, Robert Wagner, Morgana Barroso Oquendo, Dorothea Siegel-Axel, Andreas Fritsche

Mol Metab· July 2019

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Glucose, adrenaline and palmitate antagonistically regulate insulin and glucagon secretion in human pseudoislets.
Estela Lorza-Gil, Felicia Gerst, Morgana Barroso Oquendo, Ulrich Deschl, Hans-Ulrich Häring

Sci Rep· July 2019

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TGR5 Activation Promotes Stimulus-Secretion Coupling of Pancreatic β-Cells via a PKA-Dependent Pathway.
Jonas Maczewsky, Julia Kaiser, Anne Gresch, Felicia Gerst, Martina Düfer

Diabetes· February 2019

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The Expression of Aldolase B in Islets Is Negatively Associated With Insulin Secretion in Humans.
Felicia Gerst, Benjamin A Jaghutriz, Harald Staiger, Anke M Schulte, Estela Lorza-Gil

J Clin Endocrinol Metab· December 2018

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Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms.
Madhura Panse, Oliver Kluth, Estela Lorza-Gil, Gabriele Kaiser, Eckhard Mühlbauer, Felicia Gerst

PLoS One· November 2018

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Metabolic crosstalk between fatty pancreas and fatty liver: effects on local inflammation and insulin secretion.
Felicia Gerst, Robert Wagner, Gabriele Kaiser, Madhura Panse, Martin Heni

Diabetologia· November 2017

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Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance.
Sibylle Sabrautzki, Gabriele Kaiser, Gerhard K H Przemeck, Felicia Gerst, Estela Lorza-Gil

Mol Metab· October 2017

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Sunitinib specifically augments glucose-induced insulin secretion.
Stefan Z Lutz, Axel Ullrich, Hans-Ulrich Häring, Susanne Ullrich, Felicia Gerst

Cell Signal· August 2017

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Activation of extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) by free fatty acid receptor 1 (FFAR1/GPR40) protects from palmitate-induced beta cell death, but plays no role in insulin secretion.
Madhura Panse, Felicia Gerst, Gabriele Kaiser, Charlott-Amélie Teutsch, Rebecca Dölker

Cell Physiol Biochem· December 2015

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Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ.
Felicia Gerst, Gabriele Kaiser, Madhura Panse, Tina Sartorius, Anna Pujol

Diabetologia· December 2015

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Impact of the adipokine adiponectin and the hepatokine fetuin-A on the development of type 2 diabetes: prospective cohort- and cross-sectional phenotyping studies.
Norbert Stefan, Qi Sun, Andreas Fritsche, Jürgen Machann, Fritz Schick, Felicia Gerst

PLoS One· November 2014

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Fetuin-A influences vascular cell growth and production of proinflammatory and angiogenic proteins by human perivascular fat cells.
Dorothea I Siegel-Axel, Susanne Ullrich, Norbert Stefan, Kilian Rittig, Felicia Gerst

Diabetologia· May 2014

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