Publications by authors named "Axel Vater"

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Eosinophil innate immune memory after bacterial skin infection promotes allergic lung inflammation.
Mariem Radhouani, Asma Farhat, Anna Hakobyan, Sophie Zahalka, Lisabeth Pimenov, Axel Vater

Sci Immunol· April 2025

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Ultrasensitive Detection of Chemokines in Clinical Samples with Graphene-Based Field-Effect Transistors.
David Kaiser, Nikolaus Meyerbroeker, Werner Purschke, Simone Sell, Christof Neumann, Axel Vater

Adv Mater· December 2024

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Inhibition of complement factor C5a or C5aR for cholesterol crystal embolism-related vascular thrombosis with microvascular injury and its consequences.
Danyang Zhao, Chao Han, Elmina Mammadova-Bach, Kanako Watanabe-Kusunoki, Tamisa Seeko Bandeira Honda, Axel Vater

Kidney Int· November 2024

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Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis.
Sergio Ortiz-Espinosa, Xabier Morales, Yaiza Senent, Diego Alignani, Beatriz Tavira, Axel Vater

Cancer Lett· March 2022

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Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock.
Shinjini Chakraborty, Veronika Eva Winkelmann, Sonja Braumüller, Annette Palmer, Anke Schultze, Axel Vater

Sci Rep· January 2021

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Neutralizing Complement C5a Protects Mice with Pneumococcal Pulmonary Sepsis.
Holger Müller-Redetzky, Ute Kellermann, Sandra-Maria Wienhold, Birgitt Gutbier, Jasmin Lienau, Axel Vater

Anesthesiology· April 2020

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C5a Blockade Increases Regulatory T Cell Numbers and Protects Against Microvascular Loss and Epithelial Damage in Mouse Airway Allografts.
Mohammad Afzal Khan, Fatimah Alanazi, Hala Abdalrahman Ahmed, Axel Vater, Abdullah Mohammed Assiri

Front Immunol· July 2019

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Effect of a calcitonin gene-related peptide-binding L-RNA aptamer on neuronal activity in the rat spinal trigeminal nucleus.
Michael J M Fischer, Jakob Schmidt, Stanislav Koulchitsky, Sven Klussmann, Axel Vater

J Headache Pain· January 2018

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Signaling of the Complement Cleavage Product Anaphylatoxin C5a Through C5aR (CD88) Contributes to Pharmacological Hematopoietic Stem Cell Mobilization.
Kamila Bujko, Sylwia Rzeszotek, Kai Hoehlig, Jun Yan, Axel Vater

Stem Cell Rev Rep· December 2017

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Increasing Tumor-Infiltrating T Cells through Inhibition of CXCL12 with NOX-A12 Synergizes with PD-1 Blockade.
Dirk Zboralski, Kai Hoehlig, Dirk Eulberg, Anna Frömming, Axel Vater

Cancer Immunol Res· November 2017

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A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis.
Daniel Ajona, Sergio Ortiz-Espinosa, Haritz Moreno, Teresa Lozano, María J Pajares, Axel Vater

Cancer Discov· July 2017

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Low-Intensity Training and the C5a Complement Antagonist NOX-D21 Rescue the mdx Phenotype through Modulation of Inflammation.
Janek Hyzewicz, Jun Tanihata, Mutsuki Kuraoka, Yuko Nitahara-Kasahara, Teiva Beylier, Axel Vater

Am J Pathol· May 2017

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CXCL12/SDF-1-Dependent Retinal Migration of Endogenous Bone Marrow-Derived Stem Cells Improves Visual Function after Pharmacologically Induced Retinal Degeneration.
Volker Enzmann, Stéphanie Lecaudé, Anna Kruschinski, Axel Vater

Stem Cell Rev Rep· April 2017

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Intravitreal inhibition of complement C5a reduces choroidal neovascularization in mice.
Claudia Brockmann, Tobias Brockmann, Sabrina Dege, Catharina Busch, Norbert Kociok, Axel Vater

Graefes Arch Clin Exp Ophthalmol· October 2015

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Complement system modulation as a target for treatment of arrhythmogenic cardiomyopathy.
Manolis Mavroidis, Constantinos H Davos, Stelios Psarras, Aimilia Varela, Nikolaos C Athanasiadis, Axel Vater

Basic Res Cardiol· May 2015

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Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
Laure Yatime, Christian Maasch, Kai Hoehlig, Sven Klussmann, Gregers R Andersen, Axel Vater

Nat Commun· April 2015

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Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer(®) therapeutics.
Axel Vater, Sven Klussmann

Drug Discov Today· January 2015

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SDF-1 inhibition targets the bone marrow niche for cancer therapy.
Aldo M Roccaro, Antonio Sacco, Werner G Purschke, Michele Moschetta, Klaus Buchner, Axel Vater

Cell Rep· October 2014

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Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis.
Werner G Purschke, Kai Hoehlig, Klaus Buchner, Dirk Zboralski, Frank Schwoebel, Axel Vater

Biochem J· August 2014

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Peripherally circulating ghrelin does not mediate alcohol-induced reward and alcohol intake in rodents.
Elisabet Jerlhag, Lisa Ivanoff, Axel Vater, Jörgen A Engel

Alcohol Clin Exp Res· April 2014

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In vivo therapy monitoring of experimental rheumatoid arthritis in rats using near-infrared fluorescence imaging.
Sonja Vollmer, Ines Gemeinhardt, Axel Vater, Beatrix Schnorr, Jörg Schnorr

J Biomed Opt· March 2014

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A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis.
Kai Hoehlig, Christian Maasch, Nelli Shushakova, Klaus Buchner, Markus Huber-Lang, Axel Vater

Mol Ther· December 2013

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Bioactive lipids S1P and C1P are prometastatic factors in human rhabdomyosarcoma, and their tissue levels increase in response to radio/chemotherapy.
Gabriela Schneider, Ewa Bryndza, Ahmed Abdel-Latif, Janina Ratajczak, Magdalena Maj, Axel Vater

Mol Cancer Res· July 2013

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A mixed mirror-image DNA/RNA aptamer inhibits glucagon and acutely improves glucose tolerance in models of type 1 and type 2 diabetes.
Axel Vater, Simone Sell, Przemyslaw Kaczmarek, Christian Maasch, Klaus Buchner

J Biol Chem· July 2013

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Targeting complement component 5a promotes vascular integrity and limits airway remodeling.
Mohammad A Khan, Christian Maasch, Axel Vater, Sven Klussmann, John Morser

Proc Natl Acad Sci U S A· April 2013

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