Publications by authors named "B M Savall"

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Discovery of Imidazo[1,2-]pyrazines and Pyrazolo[1,5-]pyrimidines as TARP γ-8 Selective AMPAR Negative Modulators.
Brad M Savall, Dongpei Wu, Devin M Swanson, Mark Seierstad, Nyantsz Wu

ACS Med Chem Lett· March 2019

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Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8.
Suchitra Ravula, Brad M Savall, Nyantsz Wu, Brian Lord, Kevin Coe

ACS Med Chem Lett· August 2018

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Clinical Development of Histamine H Receptor Antagonists.
Robin L Thurmond, Jennifer Venable, Brad Savall, David La, Sandra Snook

Handb Exp Pharmacol· October 2017

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4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate.
Michael A Letavic, Brad M Savall, Brett D Allison, Leah Aluisio, Jose Ignacio Andres

J Med Chem· June 2017

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Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor.
Devin M Swanson, Brad M Savall, Kevin J Coe, Freddy Schoetens, Tatiana Koudriakova

J Med Chem· September 2016

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