Publications by authors named "Devin M Swanson"

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Discovery of Imidazo[1,2-]pyrazines and Pyrazolo[1,5-]pyrimidines as TARP γ-8 Selective AMPAR Negative Modulators.
Brad M Savall, Dongpei Wu, Devin M Swanson, Mark Seierstad, Nyantsz Wu

ACS Med Chem Lett· March 2019

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Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8.
Suchitra Ravula, Brad M Savall, Nyantsz Wu, Brian Lord, Kevin Coe, Devin M Swanson

ACS Med Chem Lett· August 2018

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4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate.
Michael A Letavic, Brad M Savall, Brett D Allison, Leah Aluisio, Jose Ignacio Andres, Devin M Swanson

J Med Chem· June 2017

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Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor.
Devin M Swanson, Brad M Savall, Kevin J Coe, Freddy Schoetens, Tatiana Koudriakova

J Med Chem· September 2016

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Novel benzamide-based histamine h3 receptor antagonists: the identification of two candidates for clinical development.
Michael A Letavic, Leah Aluisio, Richard Apodaca, Manoj Bajpai, Ann J Barbier, Devin M Swanson

ACS Med Chem Lett· April 2015

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The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y₂ receptor.
Devin M Swanson, Victoria D Wong, Jill A Jablonowski, Chandra Shah, Dale A Rudolph

Bioorg Med Chem Lett· September 2011

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In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor.
James R Shoblock, Natalie Welty, Diane Nepomuceno, Brian Lord, Leah Aluisio, Devin M Swanson

Psychopharmacology (Berl)· February 2010

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Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.
Devin M Swanson, Chandra R Shah, Brian Lord, Kirsten Morton, Lisa K Dvorak

Eur J Med Chem· November 2009

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Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea pigs.
Anindya Bhattacharya, Brian P Scott, Nadia Nasser, Hong Ao, Michael P Maher, Devin M Swanson

J Pharmacol Exp Ther· November 2007

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Aplysamine-1 and related analogs as histamine H3 receptor antagonists.
Devin M Swanson, Sandy J Wilson, Jamin D Boggs, Wei Xiao, Richard Apodaca

Bioorg Med Chem Lett· February 2006

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Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist.
Devin M Swanson, Adrienne E Dubin, Chandra Shah, Nadia Nasser, Leon Chang

J Med Chem· March 2005

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