Publications by authors named "Baoting Zhang"

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Harnessing Bone-Liver Crosstalk: A Dual-Action LYTAC Approach for Bone-Specific Accumulation and Liver-Specific Protein Degradation in Bone Disorders.
Yuan Ma, Gubu Amu, Yufei Pan, Hewen Jiang, Sifan Yu, Huarui Zhang, Yihao Zhang, Baoting Zhang, Ge Zhang

JACS Au· December 2025

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Macrophagic Sclerostin Loop2-ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action.
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Huarui Zhang, Yihao Zhang, Zhanghao Li, Tao Zhang, Shu Zhang, Baoting Zhang, Ge Zhang

Adv Sci (Weinh)· November 2025

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Methodological quality of systematic reviews on orally administered Chinese herbal medicine published in Chinese between 2021 and 2022: A cross-sectional study.
Yue Jiang, Claire Chenwen Zhong, Betty Huan Wang, Shan-Shan Xu, Fai Fai Ho, Bao-Ting Zhang

J Integr Med· September 2025

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Advancing Design Strategy of PROTACs for Cancer Therapy.
Hang Luo, Yuan Tian, Razack Abdullah, Baoting Zhang, Yuan Ma, Ge Zhang

MedComm (2020)· July 2025

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Author Correction: Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation.
Defang Li, Jin Liu, Baosheng Guo, Chao Liang, Lei Dang, Zongkang Zhang, Bao-Ting Zhang, Ge Zhang

Nat Commun· June 2025

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Role of Sclerostin in Cardiovascular System.
Ning Zhang, Luyao Wang, Xiaofei Li, Xin Yang, Xiaohui Tao, Baoting Zhang, Ge Zhang

Int J Mol Sci· May 2025

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DeepAptamer: Advancing high-affinity aptamer discovery with a hybrid deep learning model.
Xin Yang, Chi Ho Chan, Shanshan Yao, Hang Yin Chu, Minchuan Lyu, Zongkang Zhang, Bao-Ting Zhang, Lu Zhang, Ge Zhang

Mol Ther Nucleic Acids· March 2025

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Targeting Drug Delivery System to Skeletal Muscles: A Comprehensive Review of Different Approaches.
Xiaofang Li, Jintao Xu, Shanshan Yao, Ning Zhang, Bao-Ting Zhang, Zong-Kang Zhang

J Cachexia Sarcopenia Muscle· February 2025

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Peptide Aptamer-Paclitaxel Conjugates for Tumor Targeted Therapy.
Xinyang Shen, Yuan Ma, Hang Luo, Razack Abdullah, Yufei Pan, Yihao Zhang, Baoting Zhang, Ge Zhang

Pharmaceutics· December 2024

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Long Noncoding RNA lncRNA-3 Recruits PRC2 for MyoD1 Silencing to Suppress Muscle Regeneration During Aging.
Zong-Kang Zhang, Daogang Guan, Jintao Xu, Xiaofang Li, Ning Zhang, Ge Zhang, Bao-Ting Zhang

Int J Mol Sci· November 2024

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Targeting osteoblastic 11β-HSD1 to combat high-fat diet-induced bone loss and obesity.
Chuanxin Zhong, Nanxi Li, Shengzheng Wang, Dijie Li, Zhihua Yang, Huarui Zhang, Zhanghao Li, Yihao Zhang, Zongkang Zhang, Baoting Zhang, Ge Zhang

Nat Commun· October 2024

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SMTRI: A deep learning-based web service for predicting small molecules that target miRNA-mRNA interactions.
Huan Xiao, Yihao Zhang, Xin Yang, Sifan Yu, Ziqi Chen, Zongkang Zhang, Ge Zhang, Bao-Ting Zhang

Mol Ther Nucleic Acids· September 2024

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Aptamer functionalized hypoxia-potentiating agent and hypoxia-inducible factor inhibitor combined with hypoxia-activated prodrug for enhanced tumor therapy.
Yuan Ma, Huarui Zhang, Xinyang Shen, Xin Yang, Yan Deng, Baoting Zhang, Ge Zhang

Cancer Lett· August 2024

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Discovery of the small molecular inhibitors against sclerostin loop3 as potential anti-osteoporosis agents by structural based virtual screening and molecular design.
Sifan Yu, Weifeng Huang, Hao Zhang, Yinfeng Guo, Baoting Zhang, Ge Zhang

Eur J Med Chem· May 2024

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Unique quinoline orientations shape the modified aptamer to sclerostin for enhanced binding affinity and bone anabolic potential.
Amu Gubu, Yuan Ma, Sifan Yu, Huarui Zhang, Zefeng Chen, Yihao Zhang, Ning Zhang, Baoting Zhang, Ge Zhang

Mol Ther Nucleic Acids· March 2024

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A bimolecular modification strategy for developing long-lasting bone anabolic aptamer.
Huarui Zhang, Sifan Yu, Shuaijian Ni, Amu Gubu, Yuan Ma, Yihao Zhang, Zongkang Zhang, Baoting Zhang, Ge Zhang

Mol Ther Nucleic Acids· December 2023

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Nucleic acid amphiphiles: Synthesis, properties, and applications.
Amu Gubu, Xueli Zhang, Aiping Lu, Baoting Zhang, Yuan Ma, Ge Zhang

Mol Ther Nucleic Acids· September 2023

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The role of sclerostin in lipid and glucose metabolism disorders.
Hewen Jiang, Dijie Li, Ying Han, Nanxi Li, Xiaohui Tao, Zongkang Zhang, Ning Zhang, Yihao Zhang, Ge Zhang, Bao-Ting Zhang

Biochem Pharmacol· September 2023

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Editorial: Aptamer-based structural biology, computational modelling, translational research and drug discovery, Volume II.
Yuan Ma, Yuanyuan Yu, Baoting Zhang, Aiping Lu, Ge Zhang

Front Cell Dev Biol· May 2023

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Chemically modified aptamers for improving binding affinity to the target proteins enhanced non-covalent bonding.
Zefeng Chen, Hang Luo, Amu Gubu, Sifan Yu, Huarui Zhang, Yihao Zhang, Baoting Zhang, Ge Zhang

Front Cell Dev Biol· February 2023

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RNA-targeted small-molecule drug discoveries: a machine-learning perspective.
Huan Xiao, Xin Yang, Yihao Zhang, Zongkang Zhang, Ge Zhang, Bao-Ting Zhang

RNA Biol· January 2023

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Strategies for developing long-lasting therapeutic nucleic acid aptamer targeting circulating protein: The present and the future.
Yihao Zhang, Huarui Zhang, Daniel Wing Ho Chan, Yuan Ma, Aiping Lu, Baoting Zhang, Ge Zhang

Front Cell Dev Biol· November 2022

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Therapeutic aptamer targeting sclerostin loop3 for promoting bone formation without increasing cardiovascular risk in osteogenesis imperfecta mice.
Luyao Wang, Yuanyuan Yu, Shuaijian Ni, Dijie Li, Jin Liu, Ning Zhang, Zong-Kang Zhang, Huarui Zhang, Shu Zhang, Zhenlin Zhang, Bao-Ting Zhang, Ge Zhang

Theranostics· August 2022

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Targeting loop3 of sclerostin preserves its cardiovascular protective action and promotes bone formation.
Yuanyuan Yu, Luyao Wang, Shuaijian Ni, Dijie Li, Jin Liu, Ning Zhang, Zong-Kang Zhang, Huarui Zhang, Zhenlin Zhang, Shu Zhang, Bao-Ting Zhang, Ge Zhang

Nat Commun· July 2022

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Drug discovery of sclerostin inhibitors.
Sifan Yu, Dijie Li, Ning Zhang, Shuaijian Ni, Meiheng Sun, Zongkang Zhang, Shu Zhang, Zhenlin Zhang, Baoting Zhang, Ge Zhang

Acta Pharm Sin B· May 2022

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