Publications by authors named "Sifan Yu"

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Macrophagic Sclerostin Loop2-ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action.
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Sifan Yu, Yuanyuan Yu, Yu Huang

Adv Sci (Weinh)· November 2025

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Role of Sclerostin in Cardiovascular System.
Ning Zhang, Luyao Wang, Xiaofei Li, Xin Yang, Xiaohui Tao, Yuanyuan Yu, Sifan Yu, Yuan Ma

Int J Mol Sci· May 2025

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DeepAptamer: Advancing high-affinity aptamer discovery with a hybrid deep learning model.
Xin Yang, Chi Ho Chan, Shanshan Yao, Hang Yin Chu, Minchuan Lyu, Yuan Ma, Sifan Yu, Yuanyuan Yu

Mol Ther Nucleic Acids· March 2025

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Classifications of triple-negative breast cancer: insights and current therapeutic approaches.
Ziqi Chen, Yumeng Liu, Minchuan Lyu, Chi Ho Chan, Meiheng Sun, Sifan Yu, Yuanyuan Yu

Cell Biosci· February 2025

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Targeting osteoblastic 11β-HSD1 to combat high-fat diet-induced bone loss and obesity.
Chuanxin Zhong, Nanxi Li, Shengzheng Wang, Dijie Li, Zhihua Yang, Sifan Yu, Yuan Ma, Yuanyuan Yu, Aiping Lyu

Nat Commun· October 2024

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Sulforaphane attenuates phosgene-induced acute lung injury via the Nrf2-HO-1/NQO1 pathway.
Qianying Lu, Siyu Huang, Yanmei Zhao, Sifan Yu, Mingyu Shi

J Thorac Dis· October 2024

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SMTRI: A deep learning-based web service for predicting small molecules that target miRNA-mRNA interactions.
Huan Xiao, Yihao Zhang, Xin Yang, Sifan Yu, Ziqi Chen

Mol Ther Nucleic Acids· September 2024

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Aptamer functionalized hypoxia-potentiating agent and hypoxia-inducible factor inhibitor combined with hypoxia-activated prodrug for enhanced tumor therapy.
Yuan Ma, Huarui Zhang, Xinyang Shen, Xin Yang, Yan Deng, Yuan Tian, Yufei Pan, Sifan Yu

Cancer Lett· August 2024

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Sclerostin inhibition in rare bone diseases: Molecular understanding and therapeutic perspectives.
Tao Xiaohui, Luyao Wang, Xin Yang, Hewen Jiang, Ning Zhang, Sifan Yu, Yuan Ma, Yuanyuan Yu, Hua Yue

J Orthop Translat· July 2024

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Discovery of the small molecular inhibitors against sclerostin loop3 as potential anti-osteoporosis agents by structural based virtual screening and molecular design.
Sifan Yu, Weifeng Huang, Hao Zhang, Yinfeng Guo, Baoting Zhang

Eur J Med Chem· May 2024

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Connective Tissue Growth Factor: Regulation, Diseases, and Drug Discovery.
Meishen Ren, Shanshan Yao, Tienan Chen, Hang Luo, Xiaohui Tao, Sifan Yu

Int J Mol Sci· April 2024

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Unique quinoline orientations shape the modified aptamer to sclerostin for enhanced binding affinity and bone anabolic potential.
Amu Gubu, Yuan Ma, Sifan Yu, Huarui Zhang, Zefeng Chen, Yuanyuan Yu, Yuan Tian

Mol Ther Nucleic Acids· March 2024

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Control of Aluminum and Titanium Contents in the Electroslag Remelting of ATI 718Plus Alloy.
Lesong Li, Minqing Wang, Qintian Zhu, Xiaopeng Xu, Sifan Yu

Materials (Basel)· March 2024

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A bimolecular modification strategy for developing long-lasting bone anabolic aptamer.
Huarui Zhang, Sifan Yu, Shuaijian Ni, Amu Gubu, Yuan Ma, Yuzhe Wang, Yuanyuan Yu, Aiping Lyu

Mol Ther Nucleic Acids· December 2023

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Construction of 4-hydroxycoumarin derivatives with adjacent quaternary and tertiary stereocenters ternary catalysis.
Mengchu Zhang, Tianyuan Zhang, Sifan Yu, Huang Qiu, Abdulla Yusuf, Yu Qian

Chem Sci· November 2023

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Identification of potentially functional circRNAs and prediction of the circRNA-miRNA-hub gene network in mice with primary blast lung injury.
Qianying Lu, Junfeng Li, Yanmei Zhao, Jianfeng Zhang, Mingyu Shi, Sifan Yu

BMC Pulm Med· October 2023

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The role of sclerostin in lipid and glucose metabolism disorders.
Hewen Jiang, Dijie Li, Ying Han, Nanxi Li, Xiaohui Tao, Yuanyuan Yu, Sifan Yu

Biochem Pharmacol· September 2023

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miR-223: a key regulator of pulmonary inflammation.
Mingyu Shi, Qianying Lu, Yanmei Zhao, Ziling Ding, Sifan Yu

Front Med (Lausanne)· July 2023

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Crosstalk between Inflammation and Hemorrhage/Coagulation Disorders in Primary Blast Lung Injury.
Junfeng Li, Jianfeng Zhang, Mingyu Shi, Sifan Yu, Mengjun Ji

Biomolecules· February 2023

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Chemically modified aptamers for improving binding affinity to the target proteins enhanced non-covalent bonding.
Zefeng Chen, Hang Luo, Amu Gubu, Sifan Yu, Huarui Zhang, Yuan Ma

Front Cell Dev Biol· February 2023

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Copper-catalyzed multicomponent assembly of γ-butenolides the interception of carbonyl ylides with iminium ions.
Mengchu Zhang, Sifan Yu, Ruyu Hua, Dan Zhang, Huang Qiu

Org Biomol Chem· January 2023

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Multicomponent Assembly of Complex Oxindoles by Enantioselective Cooperative Catalysis.
Ru-Yu Hua, Si-Fan Yu, Xiao-Ting Jie, Huang Qiu, Wen-Hao Hu

Angew Chem Int Ed Engl· December 2022

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Strategies for developing long-lasting therapeutic nucleic acid aptamer targeting circulating protein: The present and the future.
Yihao Zhang, Huarui Zhang, Daniel Wing Ho Chan, Yuan Ma, Aiping Lu, Sifan Yu

Front Cell Dev Biol· November 2022

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An enantioselective four-component reaction via assembling two reaction intermediates.
Sifan Yu, Wenju Chang, Ruyu Hua, Xiaoting Jie, Mengchu Zhang

Nat Commun· November 2022

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Drug discovery of sclerostin inhibitors.
Sifan Yu, Dijie Li, Ning Zhang, Shuaijian Ni, Meiheng Sun, Yuanyuan Yu, Samuel Tin Yui Yeung

Acta Pharm Sin B· May 2022

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