Publications by authors named "Barbara Grunwald"

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Transcription factor switching drives subtype-specific pancreatic cancer.
Shalini V Rao, Lisa Young, Danya Cheeseman, Sean Flynn, Niklas Krebs

Nat Genet· December 2025

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Tumour tissue: heterogeneous, but not disordered.
Barbara T Grünwald, Rama Khokha

Nat Rev Cancer· November 2025

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Spatial distribution and subtype-specific expression patterns of Nectin-4 in muscle-invasive bladder cancer.
Csilla Olah, Lara Sichward, Boris Hadaschik, Christopher Darr, Viktor Grünwald

BJU Int· August 2025

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Whole genome and transcriptome profiling in advanced pancreatic cancer patients on the COMPASS trial.
Jennifer J Knox, Gun Ho Jang, Robert C Grant, Amy Zhang, Lucy Ma

Nat Commun· July 2025

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Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer.
Lukas Klein, Mengyu Tu, Niklas Krebs, Laura Urbach, Daniela Grimm

Nat Commun· January 2025

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Dipeptidyl-peptidase 9 regulates the dynamics of tumorigenesis and metastasis in breast cancer.
Lisa Heß, Kazeera Aliar, Barbara T Grünwald, Ricarda Griffin, Alina Lozan

Biochim Biophys Acta Mol Basis Dis· June 2024

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CellViT: Vision Transformers for precise cell segmentation and classification.
Fabian Hörst, Moritz Rempe, Lukas Heine, Constantin Seibold, Julius Keyl

Med Image Anal· May 2024

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Hourglass, a rapid analysis framework for heterogeneous bioimaging data, identifies sex disparity in IL-6/STAT3-associated immune phenotypes in pancreatic cancer.
Kazeera Aliar, Henry R Waterhouse, Foram Vyas, Niklas Krebs, Bowen Zhang

J Pathol· December 2023

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Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages.
Hyeyeon Kim, Kazeera Aliar, Pirashaanthy Tharmapalan, Curtis W McCloskey, Abhijith Kuttanamkuzhi

Cell Rep· November 2023

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Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages.
Hyeyeon Kim, Kazeera Aliar, Pirashaanthy Tharmapalan, Curtis W McCloskey, Abhijith Kuttanamkuzhi

Cell Rep· October 2023

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hENT1 as a Predictive Biomarker in PDAC-Response.
Sheron Perera, Gun Ho Jang, Robert Grant, Faiyaz Notta, Barbara Grunwald

Clin Cancer Res· August 2023

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Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers.
Joan Miguel Romero, Emma Titmuss, Yifan Wang, James Vafiadis, Alain Pacis

NPJ Precis Oncol· August 2023

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An Engineered Paper-Based 3D Coculture Model of Pancreatic Cancer to Study the Impact of Tissue Architecture and Microenvironmental Gradients on Cell Phenotype.
Jose L Cadavid, Simon Latour, Ferris Nowlan, Ileana L Co, Natalie Landon-Brace

Adv Healthc Mater· June 2023

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Systemic inflammatory prognostic scores in advanced pancreatic adenocarcinoma.
Lucy X Ma, Yifan Wang, Osvaldo Espin-Garcia, Michael J Allen, Gun Ho Jang

Br J Cancer· May 2023

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Correlation of transcriptional subtypes with a validated CT radiomics score in resectable pancreatic ductal adenocarcinoma.
Emmanuel Salinas-Miranda, Gerard M Healy, Barbara Grünwald, Rahi Jain, Dominik Deniffel

Eur Radiol· October 2022

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Glycoproteomics Identifies Plexin-B3 as a Targetable Cell Surface Protein Required for the Growth and Invasion of Triple-Negative Breast Cancer Cells.
Laura Kuhlmann, Meinusha Govindarajan, Salvador Mejia-Guerrero, Vladimir Ignatchenko, Lydia Y Liu

J Proteome Res· September 2022

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Correction: GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer.
Grainne M O'Kane, Barbara T Grünwald, Gun-Ho Jang, Mehdi Masoomian, Sarah Picardo

Clin Cancer Res· June 2022

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Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma.
Bryn Golesworthy, Yifan Wang, Amanda Tanti, Alain Pacis, Joan Miguel Romero

Front Oncol· April 2022

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Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity.
Kebria Hezaveh, Rahul S Shinde, Andreas Klötgen, Marie Jo Halaby, Sara Lamorte

Immunity· February 2022

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TIMP1 expression underlies sex disparity in liver metastasis and survival in pancreatic cancer.
Chris D Hermann, Benjamin Schoeps, Celina Eckfeld, Enkhtsetseg Munkhbaatar, Lukas Kniep

J Exp Med· November 2021

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Spatially confined sub-tumor microenvironments in pancreatic cancer.
Barbara T Grünwald, Antoine Devisme, Geoffroy Andrieux, Foram Vyas, Kazeera Aliar

Cell· October 2021

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Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill.
Vishnu Mohan, Jean P Gaffney, Inna Solomonov, Maxim Levin, Mordehay Klepfish

Cancers (Basel)· April 2021

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GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer.
Grainne M O'Kane, Barbara T Grünwald, Gun-Ho Jang, Mehdi Masoomian, Sarah Picardo

Clin Cancer Res· September 2020

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A Four-Chemokine Signature Is Associated with a T-cell-Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer.
Joan M Romero, Barbara Grünwald, Gun-Ho Jang, Prashant P Bavi, Aaditeya Jhaveri

Clin Cancer Res· April 2020

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Recognizing the Molecular Multifunctionality and Interactome of TIMP-1.
Barbara Grünwald, Benjamin Schoeps, Achim Krüger

Trends Cell Biol· January 2019

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