Publications by authors named "Kebria Hezaveh"

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A phase 1 study evaluating the safety, tolerability, and pharmacokinetics of the porcupine inhibitor, AZD5055.
Xiao-Hong Zhou, Susanne Prothon, Engin Liathdale, Nicola Ferrari, Kebria Hezaveh

iScience· June 2025

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The use of a multi-metric readout screen to identify EHMT2/G9a-inhibition as a modulator of cancer-associated fibroblast activation state.
Nila C Wu, Rene Quevedo, Michelle Nurse, Kebria Hezaveh, Haijiao Liu

Biomaterials· March 2025

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The intestinal microbiota modulates the transcriptional landscape of iNKT cells at steady-state and following antigen exposure.
Qiaochu Lin, Meggie Kuypers, Yuriy Baglaenko, Eric Cao, Kebria Hezaveh

Mucosal Immunol· April 2024

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Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy.
Michael St Paul, Samuel D Saibil, Meghan Kates, SeongJun Han, Scott C Lien, Kebria Hezaveh

Cell Rep Med· March 2024

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N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer.
Shiyan Wang, Shanshan Gao, Yong Zeng, Lin Zhu, Yulin Mo, Kebria Hezaveh

Gastroenterology· April 2022

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Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity.
Kebria Hezaveh, Rahul S Shinde, Andreas Klötgen, Marie Jo Halaby, Sara Lamorte

Immunity· February 2022

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Dynamic CD4 T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection.
Laura M Snell, Wenxi Xu, Diala Abd-Rabbo, Giselle Boukhaled, Mengdi Guo, Kebria Hezaveh

Nat Immunol· December 2021

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A network of immune and microbial modifications underlies viral persistence in the gastrointestinal tract.
Bethany L Macleod, Heidi J Elsaesser, Laura M Snell, Russell J Dickson, Mengdi Guo, Kebria Hezaveh

J Exp Med· December 2020

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YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA.
Andreas Kloetgen, Sujitha Duggimpudi, Konstantin Schuschel, Kebria Hezaveh, Daniel Picard

Int J Mol Sci· June 2020

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GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment.
Marie Jo Halaby, Kebria Hezaveh, Sara Lamorte, M Teresa Ciudad, Andreas Kloetgen

Sci Immunol· December 2019

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Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling.
Sujitha Duggimpudi, Andreas Kloetgen, Sathish Kumar Maney, Philipp C Münch, Kebria Hezaveh

J Biol Chem· October 2018

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CD8 T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity.
Laura M Snell, Bethany L MacLeod, Jaclyn C Law, Ivan Osokine, Heidi J Elsaesser, Kebria Hezaveh

Immunity· October 2018

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Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans.
Rahul Shinde, Kebria Hezaveh, Marie Jo Halaby, Andreas Kloetgen, Ankur Chakravarthy

Nat Immunol· June 2018

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T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases.
Mareike Doerrenberg, Andreas Kloetgen, Kebria Hezaveh, Wilhelm Wössmann, Kirsten Bleckmann

Genes Chromosomes Cancer· February 2017

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Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis.
Kebria Hezaveh, Andreas Kloetgen, Stephan H Bernhart, Kunal Das Mahapatra, Dido Lenze

Haematologica· November 2016

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Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.
Ute Fischer, Michael Forster, Anna Rinaldi, Thomas Risch, Stéphanie Sungalee, Kebria Hezaveh

Nat Genet· September 2015

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