Publications by authors named "Barbara L Mui"

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CD47 peptide-cloaked lipid nanoparticles promote cell-specific mRNA delivery.
Tyler Ellis Papp, Jianhao Zeng, Hamna Shahnawaz, Awurama Akyianu, Laura Breda, Barbara L Mui

Mol Ther· July 2025

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Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo.
Vladimir V Shuvaev, Ying K Tam, Benjamin W Lee, Jacob W Myerson, Alan Herbst, Barbara L Mui

Proc Natl Acad Sci U S A· July 2025

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An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.
Carlo Castruccio Castracani, Laura Breda, Tyler E Papp, Amaliris Guerra, Enrico Radaelli, Barbara L Mui

Blood· January 2025

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Use of HSC-targeted LNP to generate a mouse model of lethal α-thalassemia and treatment via lentiviral gene therapy.
Maxwell E Chappell, Laura Breda, Lucas Tricoli, Amaliris Guerra, Danuta Jarocha, Barbara L Mui

Blood· October 2024

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Bivalent norovirus mRNA vaccine elicits cellular and humoral responses protecting human enteroids from GII.4 infection.
Elena N Atochina-Vasserman, Lisa C Lindesmith, Carmen Mirabelli, Nathan A Ona, Erin K Reagan, Barbara L Mui

NPJ Vaccines· October 2024

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Physiologically based modeling of LNP-mediated delivery of mRNA in the vascular system.
Hamideh Parhiz, Vladimir V Shuvaev, Qin Li, Tyler E Papp, Awurama A Akyianu, Barbara L Mui

Mol Ther Nucleic Acids· June 2024

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Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke.
Jia Nong, Patrick M Glassman, Vladimir V Shuvaev, Sahily Reyes-Esteves, Helene C Descamps, Barbara L Mui

Mol Ther· May 2024

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In vivo hematopoietic stem cell modification by mRNA delivery.
Laura Breda, Tyler E Papp, Michael P Triebwasser, Amir Yadegari, Megan T Fedorky, Barbara L Mui

Science· July 2023

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Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke.
Jia Nong, Patrick M Glassman, Sahily Reyes-Esteves, Helene C Descamps, Vladimir V Shuvaev, Barbara L Mui

bioRxiv· June 2023

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Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses.
Mohamad-Gabriel Alameh, István Tombácz, Emily Bettini, Katlyn Lederer, Chutamath Sittplangkoon, Barbara L Mui

Immunity· June 2022

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CAR T cells produced in vivo to treat cardiac injury.
Joel G Rurik, István Tombácz, Amir Yadegari, Pedro O Méndez Fernández, Swapnil V Shewale, Barbara L Mui

Science· January 2022

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Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses.
Mohamad-Gabriel Alameh, István Tombácz, Emily Bettini, Katlyn Lederer, Chutamath Sittplangkoon, Barbara L Mui

Immunity· December 2021

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Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs.
István Tombácz, Dorottya Laczkó, Hamna Shahnawaz, Hiromi Muramatsu, Ambika Natesan, Barbara L Mui

Mol Ther· November 2021

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Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema.
Dániel Szőke, Gábor Kovács, Éva Kemecsei, László Bálint, Kitti Szoták-Ajtay, Barbara L Mui

Nat Commun· June 2021

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A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice.
Alec W Freyn, Jamile Ramos da Silva, Victoria C Rosado, Carly M Bliss, Matthew Pine, Barbara L Mui

Mol Ther· July 2020

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Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria.
Dipak K Raj, Alok Das Mohapatra, Anup Jnawali, Jenna Zuromski, Ambrish Jha, Barbara L Mui

Nature· June 2020

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Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier.
Oscar A Marcos-Contreras, Colin F Greineder, Raisa Yu Kiseleva, Hamideh Parhiz, Landis R Walsh, Barbara L Mui

Proc Natl Acad Sci U S A· February 2020

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Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice.
Elinor Willis, Norbert Pardi, Kaela Parkhouse, Barbara L Mui, Ying K Tam

Sci Transl Med· January 2020

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The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs.
Akin Akinc, Martin A Maier, Muthiah Manoharan, Kevin Fitzgerald, Muthusamy Jayaraman, Barbara L Mui

Nat Nanotechnol· December 2019

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Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin.
Hanne Huysmans, Zifu Zhong, Joyca De Temmerman, Barbara L Mui, Ying K Tam

Mol Ther Nucleic Acids· September 2019

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Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets.
Anthony Conway, Matthew Mendel, Kenneth Kim, Kyle McGovern, Alisa Boyko, Barbara L Mui

Mol Ther· April 2019

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Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques.
Norbert Pardi, Celia C LaBranche, Guido Ferrari, Derek W Cain, István Tombácz, Barbara L Mui

Mol Ther Nucleic Acids· April 2019

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PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake.
Hamideh Parhiz, Vladimir V Shuvaev, Norbert Pardi, Makan Khoshnejad, Raisa Yu Kiseleva, Barbara L Mui

J Control Release· December 2018

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Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies.
Norbert Pardi, Kaela Parkhouse, Ericka Kirkpatrick, Meagan McMahon, Seth J Zost, Barbara L Mui

Nat Commun· August 2018

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Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.
Norbert Pardi, Michael J Hogan, Martin S Naradikian, Kaela Parkhouse, Derek W Cain, Barbara L Mui

J Exp Med· June 2018

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