Publications by authors named "Barbara Molini"

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Immunization with full-length TprC variants induces a broad response to surface-exposed epitopes of the Treponema pallidum repeat protein family and is partially protective in the rabbit model of syphilis.
Lorenzo Giacani, Emily Romeis, Austin Haynes, Barbara J Molini, Lauren C Tantalo

Vaccine· August 2025

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B-Cell Epitope Mapping of the Tp0435 Immunodominant Lipoprotein for Peptide-Based Syphilis Diagnostics.
Jessica L Keane, Mahashweta Bose, Barbara J Molini, Kelika A Konda, Silver K Vargas

Diagnostics (Basel)· June 2025

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Bright New Resources for Syphilis Research: Genetically Encoded Fluorescent Tags for Treponema pallidum and Sf1Ep Cells.
Linda Grillová, Emily Romeis, Nicole A P Lieberman, Lauren C Tantalo, Linda H Xu, Barbara Molini

Mol Microbiol· October 2024

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Bright New Resources for Syphilis Research: Genetically Encoded Fluorescent Tags for and Sf1Ep Cells.
Linda Grillová, Emily Romeis, Nicole A P Lieberman, Lauren C Tantalo, Linda H Xu, Barbara Molini

bioRxiv· May 2024

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In Vitro Isolation of Treponema pallidum subsp. pallidum From Fresh and Frozen Needle Aspirates of Primary Experimental Syphilis Lesions.
Lauren C Tantalo, Barbara J Molini, Mahashweta Bose, Jeffrey D Klausner, Lorenzo Giacani

Sex Transm Dis· March 2023

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Treponema pallidum subsp. pallidum with an Artificially impaired TprK antigenic variation system is attenuated in the Rabbit model of syphilis.
Emily Romeis, Nicole A P Lieberman, Barbara Molini, Lauren C Tantalo, Benjamin Chung

PLoS Pathog· March 2023

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subsp. with an Artificially Impaired TprK Antigenic Variation System is Attenuated in the Rabbit Model of Syphilis.
Emily Romeis, Nicole A P Lieberman, Barbara Molini, Lauren C Tantalo, Benjamin Chung

bioRxiv· February 2023

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Immunization with a tri-antigen syphilis vaccine significantly attenuates chancre development, reduces bacterial load, and inhibits dissemination of Treponema pallidum.
Sheila A Lukehart, Barbara Molini, Alloysius Gomez, Charmie Godornes, Rebecca Hof

Vaccine· December 2022

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B-Cell Epitope Mapping of TprC and TprD Variants of Subspecies Informs Vaccine Development for Human Treponematoses.
Barbara Molini, Mark C Fernandez, Charmie Godornes, Anastassia Vorobieva, Sheila A Lukehart

Front Immunol· April 2022

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Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis.
Mathew A Beale, Michael Marks, Michelle J Cole, Min-Kuang Lee, Rachel Pitt, Barbara J Molini

Nat Microbiol· December 2021

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Longitudinal TprK profiling of in vivo and in vitro-propagated Treponema pallidum subsp. pallidum reveals accumulation of antigenic variants in absence of immune pressure.
Michelle J Lin, Austin M Haynes, Amin Addetia, Nicole A P Lieberman, Quynh Phung, Barbara J Molini

PLoS Negl Trop Dis· September 2021

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Survey of Treponemal Infections in Free-Ranging and Captive Macaques, 1999-2012.
Amy R Klegarth, Chigozie A Ezeonwu, Aida Rompis, Benjamin P Y-H Lee, Nantiya Aggimarangsee, Barbara J Molini

Emerg Infect Dis· May 2017

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Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains.
Barbara J Molini, Lauren C Tantalo, Sharon K Sahi, Veronica I Rodriguez, Stephanie L Brandt

Sex Transm Dis· September 2016

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Transcription of TP0126, Treponema pallidum putative OmpW homolog, is regulated by the length of a homopolymeric guanosine repeat.
Lorenzo Giacani, Stephanie L Brandt, Wujian Ke, Tara B Reid, Barbara J Molini

Infect Immun· June 2015

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Treponema pallidum subsp. pallidum TP0136 protein is heterogeneous among isolates and binds cellular and plasma fibronectin via its NH2-terminal end.
Wujian Ke, Barbara J Molini, Sheila A Lukehart, Lorenzo Giacani

PLoS Negl Trop Dis· March 2015

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Antigenic variation of TprK facilitates development of secondary syphilis.
Tara B Reid, Barbara J Molini, Mark C Fernandez, Sheila A Lukehart

Infect Immun· December 2014

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Complete Genome Sequence of the Treponema pallidum subsp. pallidum Sea81-4 Strain.
Lorenzo Giacani, Stefanie L Iverson-Cabral, Jordon C K King, Barbara J Molini, Sheila A Lukehart

Genome Announc· April 2014

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Fine analysis of genetic diversity of the tpr gene family among treponemal species, subspecies and strains.
Arturo Centurion-Lara, Lorenzo Giacani, Charmie Godornes, Barbara J Molini, Tara Brinck Reid

PLoS Negl Trop Dis· November 2013

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Footprint of positive selection in Treponema pallidum subsp. pallidum genome sequences suggests adaptive microevolution of the syphilis pathogen.
Lorenzo Giacani, Sujay Chattopadhyay, Arturo Centurion-Lara, Brendan M Jeffrey, Hoavan T Le, Barbara J Molini

PLoS Negl Trop Dis· September 2012

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Comparative investigation of the genomic regions involved in antigenic variation of the TprK antigen among treponemal species, subspecies, and strains.
Lorenzo Giacani, Stephanie L Brandt, Maritza Puray-Chavez, Tara Brinck Reid, Charmie Godornes, Barbara J Molini

J Bacteriol· August 2012

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Complete genome sequence and annotation of the Treponema pallidum subsp. pallidum Chicago strain.
Lorenzo Giacani, Brendan M Jeffrey, Barbara J Molini, HoaVan T Le, Sheila A Lukehart

J Bacteriol· May 2010

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Antigenic variation in Treponema pallidum: TprK sequence diversity accumulates in response to immune pressure during experimental syphilis.
Lorenzo Giacani, Barbara J Molini, Eric Y Kim, B Charmie Godornes, B Troy Leader

J Immunol· April 2010

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Quantitation of rabbit cytokine mRNA by real-time RT-PCR.
Charmie Godornes, Brandon Troy Leader, Barbara J Molini, Arturo Centurion-Lara, Sheila A Lukehart

Cytokine· April 2007

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Quantitative analysis of tpr gene expression in Treponema pallidum isolates: Differences among isolates and correlation with T-cell responsiveness in experimental syphilis.
Lorenzo Giacani, Barbara Molini, Charmie Godornes, Lynn Barrett, Wesley Van Voorhis

Infect Immun· January 2007

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Molecular differentiation of Treponema pallidum subspecies.
Arturo Centurion-Lara, Barbara J Molini, Charmie Godornes, Eileen Sun, Karin Hevner

J Clin Microbiol· September 2006

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