Publications by authors named "Barbara Sahagan"

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Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis.
Farzaneh Modarresi, Mohammad Ali Faghihi, Nikunj S Patel, Barbara G Sahagan, Claes Wahlestedt

Int J Alzheimers Dis· November 2011

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Diamide amino-imidazoles: a novel series of γ-secretase inhibitors for the treatment of Alzheimer's disease.
Michael A Brodney, David D Auperin, Stacey L Becker, Brian S Bronk, Tracy M Brown, Barbara G Sahagan

Bioorg Med Chem Lett· May 2011

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Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: discovery of PF-3084014.
Michael A Brodney, David D Auperin, Stacey L Becker, Brian S Bronk, Tracy M Brown, Barbara G Sahagan

Bioorg Med Chem Lett· May 2011

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The role of RAGE in amyloid-beta peptide-mediated pathology in Alzheimer's disease.
Ann Marie Schmidt, Barbara Sahagan, Robert B Nelson, Johan Selmer, Robert Rothlein

Curr Opin Investig Drugs· July 2009

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Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase.
Mohammad Ali Faghihi, Farzaneh Modarresi, Ahmad M Khalil, Douglas E Wood, Barbara G Sahagan

Nat Med· July 2008

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Thiazole-diamides as potent gamma-secretase inhibitors.
Yuhpyng L Chen, Kevin Cherry, Michael L Corman, Charles F Ebbinghaus, Chandra B Gamlath, Barbara G Sahagan

Bioorg Med Chem Lett· October 2007

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Killing pain, not neurons.
Barbara G Sahagan, Diane T Stephenson, Neil Hounslow, Dane R Liston, Pamela T Manning

Nat Med· August 2005

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Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model.
Christopher D Link, Andrew Taft, Vadim Kapulkin, Kyle Duke, Stuart Kim, Barbara G Sahagan

Neurobiol Aging· April 2003

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Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain.
Katherine E Fisher, Qing Fei, Ellen R Laird, Jeffrey L Stock, Melanie R Allen, Barbara G Sahagan

Biochemistry· July 2002

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Achieving and maintaining cognitive vitality with aging.
Howard M Fillit, Robert N Butler, Alan W O'Connell, Marilyn S Albert, James E Birren, Barbara G Sahagan

Mayo Clin Proc· July 2002

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