Publications by authors named "Barbara Vanderhyden"

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Cancer genetics and response to oncolytic virus treatment for ovarian cancer.
Erin L Fletcher, Alison O Cudmore, Barbara C Vanderhyden

Pharmacogenomics· November 2025

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Specific Genetic Mutations Impact Chemotherapy Resistance and Therapeutic Efficacy of Oncolytic Viruses in Ovarian Cancer.
Alison O Cudmore, Galaxia M Rodriguez, Vincent Maranda, Salar Farokhi Boroujeni, Humaira Murshed, Barbara C Vanderhyden

Mol Cancer Ther· October 2025

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P53 Mutation Induces Epithelial-to-Mesenchymal Transition (EMT) Associated with Stem Cell Properties and Tumorigenesis in Fallopian Tube Cells.
Kholoud Alwosaibai, Barbara C Vanderhyden, Fatimah A Alsaffar, Salma Alamri, Abdulaziz A Almotlak

Cancers (Basel)· October 2025

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Transglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment.
Dalia Ibrahim, Melanie Grondin, Kristianne Galpin, Sara Asif, Emily Thompson, Barbara C Vanderhyden

Front Immunol· August 2025

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Loss of LATS1 and LATS2 promotes ovarian tumor formation by enhancing AKT activity and PD-L1 expression.
Yalun Zhu, Atefeh Abedini, Galaxia M Rodriguez, Curtis W McCloskey, John Abou-Hamad, Barbara Vanderhyden

Oncogene· July 2025

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ILC2s in cancer: good, bad, or stay tuned?
Sara Asif, Megan Kinzel, Barbara Vanderhyden, Nicolas Jacquelot, Michele Ardolino

Trends Mol Med· July 2025

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Single-Cell RNA Sequencing to Guide Autologous Preterm Cord Mesenchymal Stromal Cell Therapy.
Chanèle Cyr-Depauw, Ivana Mižik, David P Cook, Flore Lesage, Arul Vadivel, Barbara C Vanderhyden

Am J Respir Crit Care Med· March 2025

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PTEN Loss Shapes Macrophage Dynamics in High-Grade Serous Ovarian Carcinoma.
Sarah Spear, Olivia Le Saux, Hasan B Mirza, Nayana Iyer, Katie Tyson, Barbara C Vanderhyden

Cancer Res· November 2024

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Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells.
Chanèle Cyr-Depauw, David P Cook, Ivana Mižik, Flore Lesage, Arul Vadivel, Barbara C Vanderhyden

Am J Respir Crit Care Med· September 2024

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Transcriptional regulation of the postnatal cardiac conduction system heterogeneity.
Yena Oh, Rimshah Abid, Saif Dababneh, Marwan Bakr, Termeh Aslani, Barbara C Vanderhyden

Nat Commun· August 2024

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PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway.
Jonathan J Hodgins, John Abou-Hamad, Colin Edward O'Dwyer, Ash Hagerman, Edward Yakubovich, Barbara C Vanderhyden

J Exp Med· July 2024

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FGL2 promotes tumour growth and attenuates infiltration of activated immune cells in melanoma and ovarian cancer models.
Kristianne J C Galpin, Galaxia M Rodriguez, Vincent Maranda, David P Cook, Elizabeth Macdonald, Barbara C Vanderhyden

Sci Rep· January 2024

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NLRC5 overexpression in ovarian tumors remodels the tumor microenvironment and increases T-cell reactivity toward autologous tumor-associated antigens.
Galaxia M Rodriguez, Edward Yakubovich, Humaira Murshed, Vincent Maranda, Kristianne J C Galpin, Barbara C Vanderhyden

Front Immunol· January 2024

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Unveiling the Immunogenicity of Ovarian Tumors as the Crucial Catalyst for Therapeutic Success.
Galaxia M Rodriguez, Edward Yakubovich, Barbara C Vanderhyden

Cancers (Basel)· December 2023

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Mesenchymal ovarian cancer cells promote CD8 T cell exhaustion through the LGALS3-LAG3 axis.
Edward Yakubovich, David P Cook, Galaxia M Rodriguez, Barbara C Vanderhyden

NPJ Syst Biol Appl· December 2023

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Sox10-Deficient Drug-Resistant Melanoma Cells Are Refractory to Oncolytic RNA Viruses.
John Abou-Hamad, Jonathan J Hodgins, Edward Yakubovich, Barbara C Vanderhyden, Michele Ardolino

Cells· December 2023

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Pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, sensitizes cancer cells to VSVΔ51 oncolytic virotherapy.
Boaz Wong, Anabel Bergeron, Glib Maznyi, Kristy Ng, Anna Jirovec, Barbara Vanderhyden

Mol Ther· November 2023

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Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer.
David P Cook, Kristianne J C Galpin, Galaxia M Rodriguez, Noor Shakfa, Juliette Wilson-Sanchez, Barbara C Vanderhyden

Commun Biol· November 2023

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BRCA1 and BRCA2 deficient tumour models generate distinct ovarian tumour microenvironments and differential responses to therapy.
Salar Farokhi Boroujeni, Galaxia Rodriguez, Kristianne Galpin, Edward Yakubovich, Humaira Murshed, Barbara C Vanderhyden

J Ovarian Res· November 2023

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Conventional DNA-Damaging Cancer Therapies and Emerging cGAS-STING Activation: A Review and Perspectives Regarding Immunotherapeutic Potential.
Jordan D Lewicky, Alexandrine L Martel, Mukul Raj Gupta, René Roy, Galaxia M Rodriguez, Barbara C Vanderhyden

Cancers (Basel)· August 2023

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Granulosa cell-derived miR-379-5p regulates macrophage polarization in polycystic ovarian syndrome.
Reza Salehi, Meshach Asare-Werehene, Brandon A Wyse, Atefeh Abedini, Bo Pan, Barbara Vanderhyden

Front Immunol· April 2023

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Androgen-induced exosomal miR-379-5p release determines granulosa cell fate: cellular mechanism involved in polycystic ovaries.
Reza Salehi, Brandon A Wyse, Meshach Asare-Werehene, Fereshteh Esfandiarinezhad, Atefeh Abedini, Barbara Vanderhyden

J Ovarian Res· April 2023

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Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model.
Allison Loan, Joseph Wai-Hin Leung, David P Cook, Chelsea Ko, Barbara C Vanderhyden

iScience· March 2023

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Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy lipid modulation of the tumor microenvironment.
Abera Surendran, Monire Jamalkhah, Joanna Poutou, Rayanna Birtch, Christine Lawson, Barbara Vanderhyden

Front Immunol· March 2023

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Preventing Surgery-Induced NK Cell Dysfunction Using Anti-TGF-β Immunotherapeutics.
Marisa Market, Gayashan Tennakoon, Marlena Scaffidi, David P Cook, Leonard Angka, Barbara C Vanderhyden

Int J Mol Sci· November 2022

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