Publications by authors named "Bart Lutterbach"

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Inactivation of Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade.
Cécile Gstalder, David Liu, Diana Miao, Bart Lutterbach, Alexander L DeVine

Cancer Discov· September 2020

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FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival.
Anjili Mathur, Christopher Ware, Lenora Davis, Adi Gazdar, Bo-Sheng Pan, Bart Lutterbach

PLoS One· October 2015

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Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.
Erick J Morris, Sharda Jha, Clifford R Restaino, Priya Dayananth, Hugh Zhu, Bart A Lutterbach

Cancer Discov· July 2013

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Discovery of 1-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c-Met/Ron dual kinase inhibitor with preferential affinity for the activated state of c-Met.
Alan B Northrup, Matthew H Katcher, Michael D Altman, Melissa Chenard, Matthew H Daniels, Bart Lutterbach

J Med Chem· March 2013

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Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer.
Jason D Katz, James P Jewell, David J Guerin, Jongwon Lim, Christopher J Dinsmore, Bart Lutterbach

J Med Chem· June 2011

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Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor.
Kumiko Nagashima, Stuart D Shumway, Sriram Sathyanarayanan, Albert H Chen, Brian Dolinski, Bart A Lutterbach

J Biol Chem· February 2011

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Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis.
Elisa Benedettini, Lynette M Sholl, Michael Peyton, John Reilly, Christopher Ware, Bart Lutterbach

Am J Pathol· July 2010

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MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor.
Bo-Sheng Pan, Grace K Y Chan, Melissa Chenard, An Chi, Lenora J Davis, Bart A Lutterbach

Cancer Res· February 2010

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High-throughput analysis of HGF-stimulated cell scattering.
Grace K Y Chan, Bart A Lutterbach, Bo-Sheng Pan, Ilona Kariv, Alexander A Szewczak

J Biomol Screen· October 2008

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FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.
Kaiko Kunii, Lenora Davis, Julie Gorenstein, Harold Hatch, Masakazu Yashiro, Bart Lutterbach

Cancer Res· April 2008

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Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival.
Bart Lutterbach, Qinwen Zeng, Lenora J Davis, Harold Hatch, Gaozhen Hang

Cancer Res· March 2007

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The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain.
Kristie L Durst, Bart Lutterbach, Tanawan Kummalue, Alan D Friedman, Scott W Hiebert

Mol Cell Biol· January 2003

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Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins.
Karina Barseguian, Bart Lutterbach, Scott W Hiebert, Jeffrey Nickerson, Jane B Lian

Proc Natl Acad Sci U S A· November 2002

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