Publications by authors named "Bastiaan B J Tops"

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Do we need B7-H3 immunohistochemistry for the inclusion of children with high-grade central nervous system tumors in clinical trials targeting B7-H3?
Mariëtte E G Kranendonk, Raoull Hoogendijk, Julie A S Lammers, Jasper van der Lugt, Nelleke Tolboom, Bastiaan B J Tops

Neuro Oncol· September 2025

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Implementing Pre-Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects.
Emma C Bernsen, Eugène T P Verwiel, Maaike van der Lee, Jesse J Swen, Marcel Santoso, Bastiaan B J Tops

Clin Pharmacol Ther· August 2025

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VGLL fusions define a new class of intraparenchymal central nervous system schwannoma.
Simone Schmid, Kanish Mirchia, Anna Tietze, Ilon Liu, Christin Siewert, Bastiaan B J Tops

Neuro Oncol· May 2025

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Corrigendum to "Implementation of paediatric precision oncology into clinical practice: The individualized therapies for children with cancer program 'iTHER'" [Eur J Cancer 175 (2022) 311-325].
Karin P S Langenberg, Michael T Meister, Jette J Bakhuizen, Judith M Boer, Natasha K A van Eijkelenburg, Bastiaan B J Tops

Eur J Cancer· May 2025

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Prognostic Value of the G2 Expression Signature and MYC Overexpression in Childhood High-Grade Osteosarcoma.
Roelof van Ewijk, Laura S Hiemcke-Jiwa, Jayne Y Hehir-Kwa, Nathalie Gaspar, Lianne M Haveman, Bastiaan B J Tops

JCO Precis Oncol· May 2025

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Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine.
Karin P S Langenberg, Sander R van Hooff, Bianca Koopmans, Josephine G M Strijker, Waleed M Kholosy, Bastiaan B J Tops

Eur J Cancer· March 2025

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Challenging Conventional Diagnostic Methods by Comprehensive Molecular Diagnostics: A Nationwide Prospective Comparison in Children With ALL.
Judith M Boer, Marco J Koudijs, Lennart A Kester, Edwin Sonneveld, Jayne Y Hehir-Kwa, Bastiaan B J Tops

JCO Precis Oncol· February 2025

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M&M: an RNA-seq based pan-cancer classifier for paediatric tumours.
Fleur S A Wallis, John L Baker-Hernandez, Marc van Tuil, Claudia van Hamersveld, Marco J Koudijs, Bastiaan B J Tops

EBioMedicine· January 2025

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Complex structural variation is prevalent and highly pathogenic in pediatric solid tumors.
Ianthe A E M van Belzen, Marc van Tuil, Shashi Badloe, Alex Janse, Eugène T P Verwiel, Bastiaan B J Tops

Cell Genom· November 2024

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DNA methylation-array interlaboratory comparison trial demonstrates highly reproducible paediatric CNS tumour classification across 13 international centres.
Mihaela Chirica, Philipp Jurmeister, Daniel Teichmann, Arend Koch, Eilís Perez, Bastiaan B J Tops

Neuropathol Appl Neurobiol· October 2024

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RT-PCR assay to detect fusions in formalin-fixed, paraffin-embedded glioblastoma samples.
Loudy P Priesterbach-Ackley, Joyce van Kuik, Bastiaan B J Tops, Anna Lasorella, Antonio Iavarone

Neurooncol Pract· April 2024

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Integration of RNA Sequencing, Whole Exome Sequencing, and Flow Cytometry Into Routine Diagnostic Workup of Pediatric Lymphomas.
Marijn A Scheijde-Vermeulen, Lennart A Kester, Liset Westera, Bastiaan B J Tops, Friederike A G Meyer-Wentrup

Lab Invest· January 2024

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Malignant glioma in L-2-Hydroxyglutaric Aciduria: thorough molecular characterization of a case and literature review.
Fleur Cordier, Pieter Wesseling, Bastiaan B J Tops, Lennart Kester, Pim J French

Free Neuropathol· January 2024

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Molecular diagnostic tools for the World Health Organization (WHO) 2021 classification of gliomas, glioneuronal and neuronal tumors; an EANO guideline.
Felix Sahm, Sebastian Brandner, Luca Bertero, David Capper, Pim J French, Bastiaan B J Tops

Neuro Oncol· October 2023

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Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS.
Ianthe A E M van Belzen, Casey Cai, Marc van Tuil, Shashi Badloe, Eric Strengman, Bastiaan B J Tops

BMC Cancer· July 2023

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Correction to: Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.
Michaela-Kristina Keck, Martin Sill, Andrea Wittmann, Piyush Joshi, Damian Stichel, Bastiaan B J Tops

Acta Neuropathol· April 2023

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Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.
Michaela-Kristina Keck, Martin Sill, Andrea Wittmann, Piyush Joshi, Damian Stichel, Bastiaan B J Tops

Acta Neuropathol· January 2023

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Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program 'iTHER'.
Karin P S Langenberg, Michael T Meister, Jette J Bakhuizen, Judith M Boer, Natasha K A van Eijkelenburg, Bastiaan B J Tops

Eur J Cancer· November 2022

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Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes.
Michael T Meister, Marian J A Groot Koerkamp, Terezinha de Souza, Willemijn B Breunis, Ewa Frazer-Mendelewska, Bastiaan B J Tops

EMBO Mol Med· October 2022

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Molecular Characterization Reveals Subclasses of 1q Gain in Intermediate Risk Wilms Tumors.
Ianthe A E M van Belzen, Marc van Tuil, Shashi Badloe, Eric Strengman, Alex Janse, Bastiaan B J Tops

Cancers (Basel)· October 2022

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Cost-Effectiveness of Parallel Versus Sequential Testing of Genetic Aberrations for Stage IV Non-Small-Cell Lung Cancer in the Netherlands.
Henri B Wolff, Elisabeth M P Steeghs, Zakile A Mfumbilwa, Harry J M Groen, Eddy M Adang, Bastiaan B J Tops

JCO Precis Oncol· July 2022

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Improved Gene Fusion Detection in Childhood Cancer Diagnostics Using RNA Sequencing.
Jayne Y Hehir-Kwa, Marco J Koudijs, Eugene T P Verwiel, Lennart A Kester, Marc van Tuil, Bastiaan B J Tops

JCO Precis Oncol· January 2022

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GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.
Philipp Sievers, Damian Stichel, Martin Sill, Daniel Schrimpf, Dominik Sturm, Bastiaan B J Tops

Acta Neuropathol· December 2021

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PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum.
Karam T Alhalabi, Damian Stichel, Philipp Sievers, Heike Peterziel, Alexander C Sommerkamp, Bastiaan B J Tops

Acta Neuropathol· November 2021

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-The Most Common Rearranged Gene in Soft Tissue Lesions, Which Also Occurs in Different Bone Lesions: An Updated Review.
Uta Flucke, Max M van Noesel, Vasiliki Siozopoulou, David Creytens, Bastiaan B J Tops

Diagnostics (Basel)· June 2021

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